Matches in SemOpenAlex for { <https://semopenalex.org/work/W2510836120> ?p ?o ?g. }
- W2510836120 endingPage "7402" @default.
- W2510836120 startingPage "7402" @default.
- W2510836120 abstract "Campylobacter jejuni (C. jejuni), a Gram-negative microaerophilic bacterium, is a predominant cause of bacterial foodborne gastroenteritis in humans worldwide. Despite its importance as a major foodborne pathogen, our understanding of the molecular mechanisms underlying C. jejuni stress survival and pathogenesis is limited. Inorganic polyphosphate (poly P) has been shown to play significant roles in bacterial resistance to stress and virulence in many pathogenic bacteria. C. jejuni contains the complete repertoire of enzymes required for poly P metabolism. Recent work in our laboratory and others have demonstrated that poly P controls a plethora of C. jejuni properties that impact its ability to survive in the environment as well as to colonize/infect mammalian hosts. This review article summarizes the current literature on the role of poly P in C. jejuni stress survival and virulence and discusses on how poly P-related enzymes can be exploited for therapeutic/prevention purposes. Additionally, the review article identifies potential areas for future investigation that would enhance our understanding of the role of poly P in C. jejuni and other bacteria, which ultimately would facilitate design of effective therapeutic/preventive strategies to reduce not only the burden of C. jejuni-caused foodborne infections but also of other bacterial infections in humans." @default.
- W2510836120 created "2016-09-16" @default.
- W2510836120 creator A5007063838 @default.
- W2510836120 creator A5027549998 @default.
- W2510836120 creator A5043702046 @default.
- W2510836120 creator A5087852470 @default.
- W2510836120 date "2016-01-01" @default.
- W2510836120 modified "2023-09-24" @default.
- W2510836120 title "Polyphosphate and associated enzymes as global regulators of stress response and virulence in<i>Campylobacter jejuni</i>" @default.
- W2510836120 cites W1492326072 @default.
- W2510836120 cites W1502292525 @default.
- W2510836120 cites W1514986543 @default.
- W2510836120 cites W1754108693 @default.
- W2510836120 cites W1849301422 @default.
- W2510836120 cites W1965277414 @default.
- W2510836120 cites W1965383388 @default.
- W2510836120 cites W1965930536 @default.
- W2510836120 cites W1967742456 @default.
- W2510836120 cites W1970387669 @default.
- W2510836120 cites W1970418859 @default.
- W2510836120 cites W1974381870 @default.
- W2510836120 cites W1974855874 @default.
- W2510836120 cites W1976908373 @default.
- W2510836120 cites W1977892839 @default.
- W2510836120 cites W1987486130 @default.
- W2510836120 cites W1989337144 @default.
- W2510836120 cites W1995962422 @default.
- W2510836120 cites W1998388609 @default.
- W2510836120 cites W2000708962 @default.
- W2510836120 cites W2003512608 @default.
- W2510836120 cites W2003636809 @default.
- W2510836120 cites W2016088035 @default.
- W2510836120 cites W2022412255 @default.
- W2510836120 cites W2022509550 @default.
- W2510836120 cites W2028916701 @default.
- W2510836120 cites W2039224874 @default.
- W2510836120 cites W2039850445 @default.
- W2510836120 cites W2044361821 @default.
- W2510836120 cites W2045246989 @default.
- W2510836120 cites W2046146036 @default.
- W2510836120 cites W2048757872 @default.
- W2510836120 cites W2049117820 @default.
- W2510836120 cites W2052953149 @default.
- W2510836120 cites W2053454626 @default.
- W2510836120 cites W2056391285 @default.
- W2510836120 cites W2057997239 @default.
- W2510836120 cites W2077838806 @default.
- W2510836120 cites W2079081483 @default.
- W2510836120 cites W2082965784 @default.
- W2510836120 cites W2084782886 @default.
- W2510836120 cites W2087345689 @default.
- W2510836120 cites W2095046259 @default.
- W2510836120 cites W2095247494 @default.
- W2510836120 cites W2098852054 @default.
- W2510836120 cites W2098992986 @default.
- W2510836120 cites W2102321085 @default.
- W2510836120 cites W2104599301 @default.
- W2510836120 cites W2105815799 @default.
- W2510836120 cites W2106690709 @default.
- W2510836120 cites W2109286270 @default.
- W2510836120 cites W2111415799 @default.
- W2510836120 cites W2112354162 @default.
- W2510836120 cites W2113077222 @default.
- W2510836120 cites W2116469312 @default.
- W2510836120 cites W2117288172 @default.
- W2510836120 cites W2118716661 @default.
- W2510836120 cites W2120904752 @default.
- W2510836120 cites W2122131141 @default.
- W2510836120 cites W2122225327 @default.
- W2510836120 cites W2122937264 @default.
- W2510836120 cites W2125509757 @default.
- W2510836120 cites W2128591134 @default.
- W2510836120 cites W2134062395 @default.
- W2510836120 cites W2134278998 @default.
- W2510836120 cites W2134746097 @default.
- W2510836120 cites W2136479814 @default.
- W2510836120 cites W2138726441 @default.
- W2510836120 cites W2146048088 @default.
- W2510836120 cites W2146078317 @default.
- W2510836120 cites W2150099653 @default.
- W2510836120 cites W2153078809 @default.
- W2510836120 cites W2156934007 @default.
- W2510836120 cites W2156960269 @default.
- W2510836120 cites W2157034505 @default.
- W2510836120 cites W2160677022 @default.
- W2510836120 cites W2162149175 @default.
- W2510836120 cites W2165214578 @default.
- W2510836120 cites W2165612340 @default.
- W2510836120 cites W2165659802 @default.
- W2510836120 cites W2165903181 @default.
- W2510836120 cites W2166211924 @default.
- W2510836120 cites W2166396446 @default.
- W2510836120 cites W2201427208 @default.
- W2510836120 cites W2221403536 @default.
- W2510836120 cites W2325267947 @default.
- W2510836120 cites W2326058280 @default.
- W2510836120 cites W2411978022 @default.
- W2510836120 cites W2416402749 @default.