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- W2511108375 endingPage "23" @default.
- W2511108375 startingPage "3" @default.
- W2511108375 abstract "Ischemic and hemorrhagic stroke cause marked blood–brain barrier (BBB) and neurovascular unit dysfunction in humans and in animal models. The tight junctions (TJs) that link the cerebral endothelial cells are critical for BBB function and they undergo marked modifications after stroke. Those changes contribute to increased BBB permeability, brain edema, and leukocyte infiltration, all hallmarks of stroke. This review describes the types of TJ modifications that occur after stroke (e.g., protein phosphorylation, altered protein/protein interactions, protein relocation, and degradation), the underlying mechanisms and potential therapeutic interventions. While the effects of stroke on the BBB have long been considered as secondary to neuronal injury, increasing evidence stresses the importance of neurovascular injury in stroke and that BBB damage may be a cause rather than a result of stroke-induced parenchymal damage." @default.
- W2511108375 created "2016-09-16" @default.
- W2511108375 creator A5003678910 @default.
- W2511108375 creator A5065005554 @default.
- W2511108375 date "2016-01-01" @default.
- W2511108375 modified "2023-09-23" @default.
- W2511108375 title "Structural Alterations to the Endothelial Tight Junction Complex During Stroke" @default.
- W2511108375 cites W13749613 @default.
- W2511108375 cites W1564522823 @default.
- W2511108375 cites W1566932602 @default.
- W2511108375 cites W1594129908 @default.
- W2511108375 cites W1898616287 @default.
- W2511108375 cites W1932494896 @default.
- W2511108375 cites W1957113176 @default.
- W2511108375 cites W1965180960 @default.
- W2511108375 cites W1966973412 @default.
- W2511108375 cites W1967076681 @default.
- W2511108375 cites W1967548195 @default.
- W2511108375 cites W1968940085 @default.
- W2511108375 cites W1969354081 @default.
- W2511108375 cites W1969794746 @default.
- W2511108375 cites W1971940899 @default.
- W2511108375 cites W1976319056 @default.
- W2511108375 cites W1976994600 @default.
- W2511108375 cites W1979286544 @default.
- W2511108375 cites W1979561481 @default.
- W2511108375 cites W1979812793 @default.
- W2511108375 cites W1981413499 @default.
- W2511108375 cites W1985455477 @default.
- W2511108375 cites W1988453926 @default.
- W2511108375 cites W1991134454 @default.
- W2511108375 cites W1992883702 @default.
- W2511108375 cites W1994406045 @default.
- W2511108375 cites W1995446848 @default.
- W2511108375 cites W1996003447 @default.
- W2511108375 cites W1997574458 @default.
- W2511108375 cites W1998907224 @default.
- W2511108375 cites W1999235115 @default.
- W2511108375 cites W1999959667 @default.
- W2511108375 cites W2000351290 @default.
- W2511108375 cites W2004723568 @default.
- W2511108375 cites W2005675003 @default.
- W2511108375 cites W2008640695 @default.
- W2511108375 cites W2015541518 @default.
- W2511108375 cites W2015679476 @default.
- W2511108375 cites W2016348267 @default.
- W2511108375 cites W2016355218 @default.
- W2511108375 cites W2017797252 @default.
- W2511108375 cites W2021612766 @default.
- W2511108375 cites W2021850662 @default.
- W2511108375 cites W2023520100 @default.
- W2511108375 cites W2024051719 @default.
- W2511108375 cites W2025440925 @default.
- W2511108375 cites W2025688778 @default.
- W2511108375 cites W2026822427 @default.
- W2511108375 cites W2027015202 @default.
- W2511108375 cites W2029884260 @default.
- W2511108375 cites W2032930328 @default.
- W2511108375 cites W2033259268 @default.
- W2511108375 cites W2034391159 @default.
- W2511108375 cites W2038233557 @default.
- W2511108375 cites W2039618919 @default.
- W2511108375 cites W2040509610 @default.
- W2511108375 cites W2041225773 @default.
- W2511108375 cites W2042110843 @default.
- W2511108375 cites W2043328838 @default.
- W2511108375 cites W2044640693 @default.
- W2511108375 cites W2045067290 @default.
- W2511108375 cites W2045532947 @default.
- W2511108375 cites W2050157380 @default.
- W2511108375 cites W2050525037 @default.
- W2511108375 cites W2051485229 @default.
- W2511108375 cites W2052276233 @default.
- W2511108375 cites W2053881066 @default.
- W2511108375 cites W2055660210 @default.
- W2511108375 cites W2055881161 @default.
- W2511108375 cites W2056856515 @default.
- W2511108375 cites W2057041797 @default.
- W2511108375 cites W2057695809 @default.
- W2511108375 cites W2061222352 @default.
- W2511108375 cites W2061526578 @default.
- W2511108375 cites W2062478419 @default.
- W2511108375 cites W2063174785 @default.
- W2511108375 cites W2065172289 @default.
- W2511108375 cites W2065422003 @default.
- W2511108375 cites W2067733328 @default.
- W2511108375 cites W2079966013 @default.
- W2511108375 cites W2080600302 @default.
- W2511108375 cites W2081284442 @default.
- W2511108375 cites W2082121172 @default.
- W2511108375 cites W2083101794 @default.
- W2511108375 cites W2084049757 @default.
- W2511108375 cites W2087899702 @default.
- W2511108375 cites W2088161496 @default.
- W2511108375 cites W2089254388 @default.
- W2511108375 cites W2091355057 @default.
- W2511108375 cites W2092436449 @default.
- W2511108375 cites W2093491806 @default.