FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2511119382> ?p ?o ?g. }

• W2511119382 endingPage "2727" @default.
• W2511119382 startingPage "2720" @default.
• W2511119382 abstract "Vascular endothelial growth factor (VEGF) is important in the growth and metastasis of cancer cells. In 2001, another angiogenic factor, endocrine gland‑derived VEGF (EG‑VEGF), was characterized and sequenced. EG‑VEGF activity appears to be restricted to endothelial cells derived from endocrine glands. At the molecular level, its expression is regulated by hypoxia and steroid hormones. Although VEGF and EG‑VEGF are structurally different, they function in a coordinated fashion. Since the majority of mammary tumors are hormone‑dependent, it was hypothesized that EG‑VEGF would be expressed in these tumors, and therefore, represent a potential target for anti‑angiogenic therapy. The aim of the present study was to assess the expression of VEGF, EG‑VEGF and its receptor (prokineticin receptor‑1), as well as that of breast cancer resistant protein, estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2, in 50 breast samples of infiltrating canalicular carcinoma (ICC) and their correlation with tumor staging. The samples were analyzed using reverse transcription‑quantitative polymerase chain reaction and immunohistochemistry. Both angiogenic growth factors were identified in all samples. However, in 90% of the samples, the expression level of VEGF was significantly higher than that of EG‑VEGF (P=0.024). There was no association between the expression of VEGF, EG‑VEGF or its receptor with tumor stage. In ICC, the predominant angiogenic factor expressed was VEGF. The expression level of either factor was not correlated with the tumor‑node‑metastasis stage. Although ICC is derived from endothelial cells, EG‑VEGF expression was not the predominant angiogenic/growth factor in ICC." @default.
• W2511119382 created "2016-09-16" @default.
• W2511119382 creator A5006521909 @default.
• W2511119382 creator A5018961276 @default.
• W2511119382 creator A5020320561 @default.
• W2511119382 creator A5038152993 @default.
• W2511119382 creator A5069215952 @default.
• W2511119382 creator A5078297037 @default.
• W2511119382 creator A5085972073 @default.
• W2511119382 date "2016-08-05" @default.
• W2511119382 modified "2023-09-27" @default.
• W2511119382 title "Molecular expression of vascular endothelial growth factor, prokineticin receptor-1 and other biomarkers in infiltrating canalicular carcinoma of the breast" @default.
• W2511119382 cites W1549576586 @default.
• W2511119382 cites W1705004681 @default.
• W2511119382 cites W1878472746 @default.
• W2511119382 cites W1933433305 @default.
• W2511119382 cites W1965067847 @default.
• W2511119382 cites W1968728434 @default.
• W2511119382 cites W1978092597 @default.
• W2511119382 cites W1978348877 @default.
• W2511119382 cites W1991614701 @default.
• W2511119382 cites W1992301098 @default.
• W2511119382 cites W1993494709 @default.
• W2511119382 cites W1995224853 @default.
• W2511119382 cites W1998252665 @default.
• W2511119382 cites W2017322644 @default.
• W2511119382 cites W2024644688 @default.
• W2511119382 cites W2026449959 @default.
• W2511119382 cites W2032347891 @default.
• W2511119382 cites W2032416959 @default.
• W2511119382 cites W2036022311 @default.
• W2511119382 cites W2043747831 @default.
• W2511119382 cites W2044702943 @default.
• W2511119382 cites W2045412281 @default.
• W2511119382 cites W2048047193 @default.
• W2511119382 cites W2051098058 @default.
• W2511119382 cites W2057366643 @default.
• W2511119382 cites W2076243964 @default.
• W2511119382 cites W2083280176 @default.
• W2511119382 cites W2084757756 @default.
• W2511119382 cites W2095804687 @default.
• W2511119382 cites W2095893831 @default.
• W2511119382 cites W2096356516 @default.
• W2511119382 cites W2097255042 @default.
• W2511119382 cites W2101382252 @default.
• W2511119382 cites W2104409728 @default.
• W2511119382 cites W2104638648 @default.
• W2511119382 cites W2114109279 @default.
• W2511119382 cites W2116760308 @default.
• W2511119382 cites W2118386164 @default.
• W2511119382 cites W2121139881 @default.
• W2511119382 cites W2131816567 @default.
• W2511119382 cites W2135911056 @default.
• W2511119382 cites W2137459358 @default.
• W2511119382 cites W2145399001 @default.
• W2511119382 cites W2149295320 @default.
• W2511119382 cites W2156367614 @default.
• W2511119382 cites W2172359919 @default.
• W2511119382 cites W2259802687 @default.
• W2511119382 cites W2402915576 @default.
• W2511119382 cites W2409685048 @default.
• W2511119382 cites W2439344486 @default.
• W2511119382 cites W2492195922 @default.
• W2511119382 cites W2604190323 @default.
• W2511119382 cites W63702685 @default.
• W2511119382 cites W95082452 @default.
• W2511119382 doi "https://doi.org/10.3892/ol.2016.4961" @default.
• W2511119382 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5038911" @default.
• W2511119382 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27703528" @default.
• W2511119382 hasPublicationYear "2016" @default.
• W2511119382 type Work @default.
• W2511119382 sameAs 2511119382 @default.
• W2511119382 citedByCount "6" @default.
• W2511119382 countsByYear W25111193822017 @default.
• W2511119382 countsByYear W25111193822019 @default.
• W2511119382 countsByYear W25111193822020 @default.
• W2511119382 countsByYear W25111193822021 @default.
• W2511119382 countsByYear W25111193822023 @default.
• W2511119382 crossrefType "journal-article" @default.
• W2511119382 hasAuthorship W2511119382A5006521909 @default.
• W2511119382 hasAuthorship W2511119382A5018961276 @default.
• W2511119382 hasAuthorship W2511119382A5020320561 @default.
• W2511119382 hasAuthorship W2511119382A5038152993 @default.
• W2511119382 hasAuthorship W2511119382A5069215952 @default.
• W2511119382 hasAuthorship W2511119382A5078297037 @default.
• W2511119382 hasAuthorship W2511119382A5085972073 @default.
• W2511119382 hasBestOaLocation W25111193821 @default.
• W2511119382 hasConcept C103041312 @default.
• W2511119382 hasConcept C121608353 @default.
• W2511119382 hasConcept C126322002 @default.
• W2511119382 hasConcept C134018914 @default.
• W2511119382 hasConcept C146285616 @default.
• W2511119382 hasConcept C167734588 @default.
• W2511119382 hasConcept C204232928 @default.
• W2511119382 hasConcept C2777025900 @default.
• W2511119382 hasConcept C2780394083 @default.
• W2511119382 hasConcept C31194975 @default.
• W2511119382 hasConcept C502942594 @default.

• next