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• W2511138529 abstract "Tryptanthrin is one of the most important members of indoloquinoline alkaloids. We obtained this alkaloid from Isatis. Two novel FeII and CoII complexes of tryptanthrin were first synthesized. Single-crystal X-ray diffraction analyses show that these complexes display distorted four-coordinated tetrahedron geometry via two heterocyclic nitrogen and oxygen atoms from tryptanthrin ligand. Binding with G-quadruplex DNA properties revealed that both complexes were found to exhibit significant interaction with G-quadruplex DNA. This study may potentially serve as the basis of future rational design of metal-based drugs from natural products that target the G-quadruplex DNA." @default.
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• W2511138529 date "2016-01-01" @default.
• W2511138529 modified "2023-10-18" @default.
• W2511138529 title "NovelFeIIandCoIIComplexes of Natural Product Tryptanthrin: Synthesis and Binding with G-Quadruplex DNA" @default.
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• W2511138529 doi "https://doi.org/10.1155/2016/5075847" @default.
• W2511138529 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5029049" @default.
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