FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2511160324> ?p ?o ?g. }

• W2511160324 endingPage "558" @default.
• W2511160324 startingPage "553" @default.
• W2511160324 abstract "Phosphatidylcholine (PC) from egg yolk is a bioactive substance with various beneficial effects, including anti-inflammatory and anti-oxidant effects. Recently, this substance has been reported to prevent acute hepatotoxicity. In the present study, we aimed to evaluate the putative protective effect of PC on carbon tetrachloride (CCl4)-induced nephrotoxicity in ICR mice. Many previous studies demonstrated that CCl4 induces nephrotoxicity resulting in renal oxidative damage. CCl4 in corn oil (0.1 ml, 1.2 g/kg) was intra-peritoneally injected into 7-week-old ICR mice twice a week. PC in corn oil (0.1 ml, 100 mg/kg) was then orally injected daily for a week. In 7 days, blood urea nitrogen (BUN) and creatinine concentrations had significantly increased in the CCl4 group compared to the control group, whereas the PC and CCl4 co-injected group had significantly decreased BUN and creatinine concentrations compared to the CCl4 group. Comparative analysis of histopathological injuries revealed that PC abrogated the nephrotoxicity of CCl4 at 7 days. Accordingly, PC also improved renal fibrosis induced by CCl4. Various biomarkers associated with oxidative damage appeared to be up-regulated in the CCl4 group, whereas in the PC and CCl4 co-injected group, levels of oxidative damage significantly decreased. Aquaporin1 (AQP1), an important water transport protein in the kidney, was down regulated in the CCl4 group compared to the control group. PC counteracted this effect. These results strongly suggest that PC can protect against oxidative damage induced by CCl4 in the kidney and enhance recovery from renal disorders." @default.
• W2511160324 created "2016-09-16" @default.
• W2511160324 creator A5022462467 @default.
• W2511160324 creator A5081370211 @default.
• W2511160324 creator A5082734393 @default.
• W2511160324 creator A5085997575 @default.
• W2511160324 date "2016-11-01" @default.
• W2511160324 modified "2023-09-26" @default.
• W2511160324 title "In vivo protective effect of phosphatidylcholine on carbon tetrachloride induced nephrotoxicity" @default.
• W2511160324 cites W1549508257 @default.
• W2511160324 cites W1975348689 @default.
• W2511160324 cites W1980420821 @default.
• W2511160324 cites W1987002424 @default.
• W2511160324 cites W1997325187 @default.
• W2511160324 cites W2007354148 @default.
• W2511160324 cites W2010290564 @default.
• W2511160324 cites W2011121342 @default.
• W2511160324 cites W2016490468 @default.
• W2511160324 cites W2024698179 @default.
• W2511160324 cites W2026684949 @default.
• W2511160324 cites W2027389066 @default.
• W2511160324 cites W2041508296 @default.
• W2511160324 cites W2049870923 @default.
• W2511160324 cites W2072883356 @default.
• W2511160324 cites W2073243840 @default.
• W2511160324 cites W2078592699 @default.
• W2511160324 cites W2084642156 @default.
• W2511160324 cites W2091196589 @default.
• W2511160324 cites W2093073105 @default.
• W2511160324 cites W2108441239 @default.
• W2511160324 cites W2149951827 @default.
• W2511160324 cites W2153462373 @default.
• W2511160324 cites W2153780021 @default.
• W2511160324 cites W4293247451 @default.
• W2511160324 doi "https://doi.org/10.1016/j.etp.2016.08.005" @default.
• W2511160324 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27575989" @default.
• W2511160324 hasPublicationYear "2016" @default.
• W2511160324 type Work @default.
• W2511160324 sameAs 2511160324 @default.
• W2511160324 citedByCount "18" @default.
• W2511160324 countsByYear W25111603242017 @default.
• W2511160324 countsByYear W25111603242018 @default.
• W2511160324 countsByYear W25111603242019 @default.
• W2511160324 countsByYear W25111603242020 @default.
• W2511160324 countsByYear W25111603242021 @default.
• W2511160324 countsByYear W25111603242022 @default.
• W2511160324 countsByYear W25111603242023 @default.
• W2511160324 crossrefType "journal-article" @default.
• W2511160324 hasAuthorship W2511160324A5022462467 @default.
• W2511160324 hasAuthorship W2511160324A5081370211 @default.
• W2511160324 hasAuthorship W2511160324A5082734393 @default.
• W2511160324 hasAuthorship W2511160324A5085997575 @default.
• W2511160324 hasConcept C102124568 @default.
• W2511160324 hasConcept C126189478 @default.
• W2511160324 hasConcept C126322002 @default.
• W2511160324 hasConcept C178790620 @default.
• W2511160324 hasConcept C185592680 @default.
• W2511160324 hasConcept C2776151105 @default.
• W2511160324 hasConcept C2777359374 @default.
• W2511160324 hasConcept C2778176769 @default.
• W2511160324 hasConcept C2778206080 @default.
• W2511160324 hasConcept C2780091579 @default.
• W2511160324 hasConcept C2780306776 @default.
• W2511160324 hasConcept C55493867 @default.
• W2511160324 hasConcept C71924100 @default.
• W2511160324 hasConcept C98274493 @default.
• W2511160324 hasConceptScore W2511160324C102124568 @default.
• W2511160324 hasConceptScore W2511160324C126189478 @default.
• W2511160324 hasConceptScore W2511160324C126322002 @default.
• W2511160324 hasConceptScore W2511160324C178790620 @default.
• W2511160324 hasConceptScore W2511160324C185592680 @default.
• W2511160324 hasConceptScore W2511160324C2776151105 @default.
• W2511160324 hasConceptScore W2511160324C2777359374 @default.
• W2511160324 hasConceptScore W2511160324C2778176769 @default.
• W2511160324 hasConceptScore W2511160324C2778206080 @default.
• W2511160324 hasConceptScore W2511160324C2780091579 @default.
• W2511160324 hasConceptScore W2511160324C2780306776 @default.
• W2511160324 hasConceptScore W2511160324C55493867 @default.
• W2511160324 hasConceptScore W2511160324C71924100 @default.
• W2511160324 hasConceptScore W2511160324C98274493 @default.
• W2511160324 hasIssue "10" @default.
• W2511160324 hasLocation W25111603241 @default.
• W2511160324 hasLocation W25111603242 @default.
• W2511160324 hasOpenAccess W2511160324 @default.
• W2511160324 hasPrimaryLocation W25111603241 @default.
• W2511160324 hasRelatedWork W1975634768 @default.
• W2511160324 hasRelatedWork W2016228605 @default.
• W2511160324 hasRelatedWork W2068217466 @default.
• W2511160324 hasRelatedWork W2106188053 @default.
• W2511160324 hasRelatedWork W2151756847 @default.
• W2511160324 hasRelatedWork W2155342874 @default.
• W2511160324 hasRelatedWork W2409903851 @default.
• W2511160324 hasRelatedWork W2414591264 @default.
• W2511160324 hasRelatedWork W2511160324 @default.
• W2511160324 hasRelatedWork W3025884475 @default.
• W2511160324 hasVolume "68" @default.
• W2511160324 isParatext "false" @default.
• W2511160324 isRetracted "false" @default.

• next