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- W2511166757 abstract "Heart rhythms arise from electrical activity generated by precisely timed opening and closing of ion channels in individual cardiac myocytes. Opening of the primary cardiac voltage-gated sodium (NaV1.5) channel initiates cellular depolarization and the propagation of an electrical action potential that promotes coordinated contraction of the heart. The regularity of these contractile waves is critically important since it drives the primary function of the heart: to act as a pump that delivers blood to the brain and vital organs. When electrical activity goes awry during a cardiac arrhythmia, the pump does not function, the brain does not receive oxygenated blood, and death ensues. Perturbations to NaV1.5 may alter the structure, and hence the function, of the ion channel and are associated downstream with a wide variety of cardiac conduction pathologies, such as arrhythmias." @default.
- W2511166757 created "2016-09-16" @default.
- W2511166757 creator A5031553126 @default.
- W2511166757 creator A5055449255 @default.
- W2511166757 date "2016-01-01" @default.
- W2511166757 modified "2023-10-16" @default.
- W2511166757 title "Cardiac Na Channels" @default.
- W2511166757 cites W1496192961 @default.
- W2511166757 cites W1551685734 @default.
- W2511166757 cites W1583128097 @default.
- W2511166757 cites W1913287761 @default.
- W2511166757 cites W1968903551 @default.
- W2511166757 cites W1969054288 @default.
- W2511166757 cites W1969120794 @default.
- W2511166757 cites W1969154199 @default.
- W2511166757 cites W1972425904 @default.
- W2511166757 cites W1972459374 @default.
- W2511166757 cites W1973239890 @default.
- W2511166757 cites W1973420297 @default.
- W2511166757 cites W1975793339 @default.
- W2511166757 cites W1977697532 @default.
- W2511166757 cites W1980306855 @default.
- W2511166757 cites W1983187084 @default.
- W2511166757 cites W1983519301 @default.
- W2511166757 cites W1985654484 @default.
- W2511166757 cites W1986189584 @default.
- W2511166757 cites W1986688964 @default.
- W2511166757 cites W1986749819 @default.
- W2511166757 cites W1987382493 @default.
- W2511166757 cites W1989095507 @default.
- W2511166757 cites W1991649249 @default.
- W2511166757 cites W1993501461 @default.
- W2511166757 cites W1996437700 @default.
- W2511166757 cites W1996943772 @default.
- W2511166757 cites W1999108741 @default.
- W2511166757 cites W1999196432 @default.
- W2511166757 cites W2000200816 @default.
- W2511166757 cites W2002215790 @default.
- W2511166757 cites W2002568518 @default.
- W2511166757 cites W2008100921 @default.
- W2511166757 cites W2012008365 @default.
- W2511166757 cites W2013666247 @default.
- W2511166757 cites W2016922659 @default.
- W2511166757 cites W2018812718 @default.
- W2511166757 cites W2019268667 @default.
- W2511166757 cites W2019316048 @default.
- W2511166757 cites W2019872702 @default.
- W2511166757 cites W2021120349 @default.
- W2511166757 cites W2023208565 @default.
- W2511166757 cites W2024218731 @default.
- W2511166757 cites W2024519643 @default.
- W2511166757 cites W2024695712 @default.
- W2511166757 cites W2026296218 @default.
- W2511166757 cites W2026779854 @default.
- W2511166757 cites W2028600729 @default.
- W2511166757 cites W2029106333 @default.
- W2511166757 cites W2029988619 @default.
- W2511166757 cites W2030423275 @default.
- W2511166757 cites W2030583987 @default.
- W2511166757 cites W2030695893 @default.
- W2511166757 cites W2031397869 @default.
- W2511166757 cites W2032030268 @default.
- W2511166757 cites W2032077935 @default.
- W2511166757 cites W2033940966 @default.
- W2511166757 cites W2036739812 @default.
- W2511166757 cites W2037903288 @default.
- W2511166757 cites W2038742469 @default.
- W2511166757 cites W2039844517 @default.
- W2511166757 cites W2041237692 @default.
- W2511166757 cites W2042089391 @default.
- W2511166757 cites W2045493336 @default.
- W2511166757 cites W2047220789 @default.
- W2511166757 cites W2050472057 @default.
- W2511166757 cites W2051760374 @default.
- W2511166757 cites W2053959834 @default.
- W2511166757 cites W2054336104 @default.
- W2511166757 cites W2056248932 @default.
- W2511166757 cites W2057507061 @default.
- W2511166757 cites W2058705889 @default.
- W2511166757 cites W2059581759 @default.
- W2511166757 cites W2063482843 @default.
- W2511166757 cites W2064163649 @default.
- W2511166757 cites W2065667098 @default.
- W2511166757 cites W2068995617 @default.
- W2511166757 cites W2070249204 @default.
- W2511166757 cites W2077047903 @default.
- W2511166757 cites W2077682807 @default.
- W2511166757 cites W2078950964 @default.
- W2511166757 cites W2079044818 @default.
- W2511166757 cites W2081904592 @default.
- W2511166757 cites W2082563883 @default.
- W2511166757 cites W2085139245 @default.
- W2511166757 cites W2085355244 @default.
- W2511166757 cites W2085873341 @default.
- W2511166757 cites W2087424870 @default.
- W2511166757 cites W2090132841 @default.
- W2511166757 cites W2094193659 @default.
- W2511166757 cites W2096306821 @default.