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- W2511220210 abstract "An early age and tumor multifocality at diagnosis, as well as a positive family history, are presently considered major risk factors in the development of metachronous tumors in the fellow eye in unilateral retinoblastoma. In order to verify these assumptions we performed an investigation on a series of 167 unilateral retinoblastoma, and found that metachronous tumors in the fellow eye were observed: 1) in 11 out of 167 patients (6.5%), globally; 2) in 3 out of the 12 patients (7.1%) with a positive family history; 3) in but one of the 23 patients showing multiple foci at diagnosis. Since the three patients with a positive family history who later developed tumors in the fellow eye, in the present series, were all diagnosed at the ages of less than 4 months, we conclude that an early age at diagnosis is the only relevant risk factor for metachronous tumor development in retinoblastoma." @default.
- W2511220210 created "2016-09-16" @default.
- W2511220210 date "2006-01-01" @default.
- W2511220210 modified "2023-09-26" @default.
- W2511220210 title "Age At Diagnosis And Bilateralization Of Unilateral Retinoblastoma" @default.
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- W2511220210 doi "https://doi.org/10.5580/11a5" @default.
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