Matches in SemOpenAlex for { <https://semopenalex.org/work/W2511346472> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2511346472 endingPage "271" @default.
- W2511346472 startingPage "268" @default.
- W2511346472 abstract "Protein expression can be controlled via AUG sequences located upstream to the initiation codon in the 5' end untranslated region (5' UTR). Our study was focused on the effect of distance between the initiation codon and the first upstream AUG. An inhibitory effect on protein expression was established when AUG exists in 5' UTR, and this effect is increased when multiple AUG sequences occur there. The study was performed with ATG16L2, a non-lethal gene with no introns or upstream AUG sequence to avoid any interference. New mutations were generated at different locations within the promoter region of ATG16L2 gene and added to a plasmid construct containing a luciferase gene reporter gene. The results show a clear relationship between the distance of the novel AUGs from initiation codon and protein expression. The inhibitory effect was even stronger when multiple AUG sequences were present in 5' UTR." @default.
- W2511346472 created "2016-09-16" @default.
- W2511346472 creator A5023232532 @default.
- W2511346472 creator A5026130264 @default.
- W2511346472 date "2016-12-01" @default.
- W2511346472 modified "2023-10-03" @default.
- W2511346472 title "Proximity of AUG sequences to initiation codon in genomic 5′ UTR regulates mammalian protein expression" @default.
- W2511346472 cites W1969210187 @default.
- W2511346472 cites W2000137108 @default.
- W2511346472 cites W2013072744 @default.
- W2511346472 cites W2033403225 @default.
- W2511346472 cites W2042732915 @default.
- W2511346472 cites W2052501792 @default.
- W2511346472 cites W2061921466 @default.
- W2511346472 cites W2062299199 @default.
- W2511346472 cites W2065905166 @default.
- W2511346472 cites W2074370703 @default.
- W2511346472 cites W2110511794 @default.
- W2511346472 cites W2138869039 @default.
- W2511346472 cites W2144548050 @default.
- W2511346472 cites W2152974197 @default.
- W2511346472 cites W2154241726 @default.
- W2511346472 cites W2169866370 @default.
- W2511346472 doi "https://doi.org/10.1016/j.gene.2016.08.052" @default.
- W2511346472 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27613142" @default.
- W2511346472 hasPublicationYear "2016" @default.
- W2511346472 type Work @default.
- W2511346472 sameAs 2511346472 @default.
- W2511346472 citedByCount "4" @default.
- W2511346472 countsByYear W25113464722017 @default.
- W2511346472 countsByYear W25113464722020 @default.
- W2511346472 countsByYear W25113464722022 @default.
- W2511346472 crossrefType "journal-article" @default.
- W2511346472 hasAuthorship W2511346472A5023232532 @default.
- W2511346472 hasAuthorship W2511346472A5026130264 @default.
- W2511346472 hasConcept C104317684 @default.
- W2511346472 hasConcept C105580179 @default.
- W2511346472 hasConcept C12464233 @default.
- W2511346472 hasConcept C141231307 @default.
- W2511346472 hasConcept C153911025 @default.
- W2511346472 hasConcept C176990463 @default.
- W2511346472 hasConcept C22667442 @default.
- W2511346472 hasConcept C54355233 @default.
- W2511346472 hasConcept C86803240 @default.
- W2511346472 hasConcept C87253356 @default.
- W2511346472 hasConcept C89604277 @default.
- W2511346472 hasConcept C94671646 @default.
- W2511346472 hasConceptScore W2511346472C104317684 @default.
- W2511346472 hasConceptScore W2511346472C105580179 @default.
- W2511346472 hasConceptScore W2511346472C12464233 @default.
- W2511346472 hasConceptScore W2511346472C141231307 @default.
- W2511346472 hasConceptScore W2511346472C153911025 @default.
- W2511346472 hasConceptScore W2511346472C176990463 @default.
- W2511346472 hasConceptScore W2511346472C22667442 @default.
- W2511346472 hasConceptScore W2511346472C54355233 @default.
- W2511346472 hasConceptScore W2511346472C86803240 @default.
- W2511346472 hasConceptScore W2511346472C87253356 @default.
- W2511346472 hasConceptScore W2511346472C89604277 @default.
- W2511346472 hasConceptScore W2511346472C94671646 @default.
- W2511346472 hasFunder F4320320300 @default.
- W2511346472 hasFunder F4320334923 @default.
- W2511346472 hasIssue "2" @default.
- W2511346472 hasLocation W25113464721 @default.
- W2511346472 hasLocation W25113464722 @default.
- W2511346472 hasOpenAccess W2511346472 @default.
- W2511346472 hasPrimaryLocation W25113464721 @default.
- W2511346472 hasRelatedWork W1992853266 @default.
- W2511346472 hasRelatedWork W2028299201 @default.
- W2511346472 hasRelatedWork W2070424978 @default.
- W2511346472 hasRelatedWork W2081247313 @default.
- W2511346472 hasRelatedWork W2084640292 @default.
- W2511346472 hasRelatedWork W2109672343 @default.
- W2511346472 hasRelatedWork W2126336673 @default.
- W2511346472 hasRelatedWork W2134153269 @default.
- W2511346472 hasRelatedWork W2971876915 @default.
- W2511346472 hasRelatedWork W3147519913 @default.
- W2511346472 hasVolume "594" @default.
- W2511346472 isParatext "false" @default.
- W2511346472 isRetracted "false" @default.
- W2511346472 magId "2511346472" @default.
- W2511346472 workType "article" @default.