FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2511396506> ?p ?o ?g. }

• W2511396506 endingPage "363" @default.
• W2511396506 startingPage "356" @default.
• W2511396506 abstract "Summary New data suggest the involvement of rotavirus (RV) in triggering autoimmunity in coeliac disease (CD) by molecular mimicry between the human-transglutaminase protein and the dodecapeptide (260-271 aa) of the RV protein VP7 (pVP7). To assess the role of RV in the onset of CD, we measured anti-pVP7 antibodies in the sera of children with CD and of control groups. We analysed serum samples of 118 biopsy-proven CD patients and 46 patients with potential CD; 32 children with other gastrointestinal diseases; 107 no-CD children and 107 blood donors. Using enzyme-linked immunosorbent assay (ELISA) assay, we measured immunoglobulin (Ig)A–IgG antibodies against the synthetic peptides pVP7, the human transglutaminase-derived peptide (476–487 aa) which shows a homology with VP7 protein and a control peptide. The triple-layered RV particles (TLPs) containing the VP7 protein and the double-layered RV-particles (DLPs) lacking the VP7 protein were also used as antigens in ELISA assay. Antibody reactivity to the RV-TLPs was positive in 22 of 118 (18%) CD patients and in both paediatric (17 of 107, 16%) and adult (29 of 107, 27%) control groups, without showing a statistically significant difference among them (P = 0·6, P = 0·1). Biopsy-proven CD patients as well as the adult control group demonstrated a high positive antibody reactivity against both pVP7 (34 of 118, 29% CD patients; 66 of 107, 62% adult controls) and control synthetic peptides (35 of 118, 30% CD patients; 56 of 107, 52% adult controls), suggesting a non-specific response against RV pVP7. We show that children with CD do not have higher immune reactivity to RV, thus questioning the molecular mimicry mechanism as a triggering factor of CD." @default.
• W2511396506 created "2016-09-16" @default.
• W2511396506 creator A5004945407 @default.
• W2511396506 creator A5008935005 @default.
• W2511396506 creator A5013961355 @default.
• W2511396506 creator A5014046124 @default.
• W2511396506 creator A5022332197 @default.
• W2511396506 creator A5030451410 @default.
• W2511396506 creator A5054015965 @default.
• W2511396506 creator A5066546570 @default.
• W2511396506 creator A5067728360 @default.
• W2511396506 creator A5067832764 @default.
• W2511396506 creator A5070876800 @default.
• W2511396506 date "2016-09-29" @default.
• W2511396506 modified "2023-10-17" @default.
• W2511396506 title "Lack of evidence of rotavirus-dependent molecular mimicry as a trigger of coeliac disease" @default.
• W2511396506 cites W111924924 @default.
• W2511396506 cites W1635858284 @default.
• W2511396506 cites W1684172555 @default.
• W2511396506 cites W1787452263 @default.
• W2511396506 cites W1952543825 @default.
• W2511396506 cites W1965089650 @default.
• W2511396506 cites W1966788203 @default.
• W2511396506 cites W1969045804 @default.
• W2511396506 cites W1994513293 @default.
• W2511396506 cites W1998268789 @default.
• W2511396506 cites W2015999293 @default.
• W2511396506 cites W2027361444 @default.
• W2511396506 cites W2029023214 @default.
• W2511396506 cites W2030761948 @default.
• W2511396506 cites W2033170005 @default.
• W2511396506 cites W2049225388 @default.
• W2511396506 cites W2071083964 @default.
• W2511396506 cites W2091852797 @default.
• W2511396506 cites W2097682417 @default.
• W2511396506 cites W2100548379 @default.
• W2511396506 cites W2104305294 @default.
• W2511396506 cites W2118564683 @default.
• W2511396506 cites W2125175765 @default.
• W2511396506 cites W2134480658 @default.
• W2511396506 cites W2135373024 @default.
• W2511396506 cites W2148945107 @default.
• W2511396506 cites W2154197712 @default.
• W2511396506 cites W2155275047 @default.
• W2511396506 cites W2167005365 @default.
• W2511396506 cites W2322022269 @default.
• W2511396506 cites W4242456586 @default.
• W2511396506 cites W4245522537 @default.
• W2511396506 doi "https://doi.org/10.1111/cei.12855" @default.
• W2511396506 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5108075" @default.
• W2511396506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27548641" @default.
• W2511396506 hasPublicationYear "2016" @default.
• W2511396506 type Work @default.
• W2511396506 sameAs 2511396506 @default.
• W2511396506 citedByCount "14" @default.
• W2511396506 countsByYear W25113965062017 @default.
• W2511396506 countsByYear W25113965062018 @default.
• W2511396506 countsByYear W25113965062019 @default.
• W2511396506 countsByYear W25113965062020 @default.
• W2511396506 countsByYear W25113965062022 @default.
• W2511396506 countsByYear W25113965062023 @default.
• W2511396506 crossrefType "journal-article" @default.
• W2511396506 hasAuthorship W2511396506A5004945407 @default.
• W2511396506 hasAuthorship W2511396506A5008935005 @default.
• W2511396506 hasAuthorship W2511396506A5013961355 @default.
• W2511396506 hasAuthorship W2511396506A5014046124 @default.
• W2511396506 hasAuthorship W2511396506A5022332197 @default.
• W2511396506 hasAuthorship W2511396506A5030451410 @default.
• W2511396506 hasAuthorship W2511396506A5054015965 @default.
• W2511396506 hasAuthorship W2511396506A5066546570 @default.
• W2511396506 hasAuthorship W2511396506A5067728360 @default.
• W2511396506 hasAuthorship W2511396506A5067832764 @default.
• W2511396506 hasAuthorship W2511396506A5070876800 @default.
• W2511396506 hasBestOaLocation W25113965061 @default.
• W2511396506 hasConcept C126322002 @default.
• W2511396506 hasConcept C147483822 @default.
• W2511396506 hasConcept C159654299 @default.
• W2511396506 hasConcept C163764329 @default.
• W2511396506 hasConcept C178498320 @default.
• W2511396506 hasConcept C181199279 @default.
• W2511396506 hasConcept C203014093 @default.
• W2511396506 hasConcept C2522874641 @default.
• W2511396506 hasConcept C2777119779 @default.
• W2511396506 hasConcept C2779134260 @default.
• W2511396506 hasConcept C2780130043 @default.
• W2511396506 hasConcept C2780349322 @default.
• W2511396506 hasConcept C2781367151 @default.
• W2511396506 hasConcept C55493867 @default.
• W2511396506 hasConcept C71924100 @default.
• W2511396506 hasConcept C86803240 @default.
• W2511396506 hasConceptScore W2511396506C126322002 @default.
• W2511396506 hasConceptScore W2511396506C147483822 @default.
• W2511396506 hasConceptScore W2511396506C159654299 @default.
• W2511396506 hasConceptScore W2511396506C163764329 @default.
• W2511396506 hasConceptScore W2511396506C178498320 @default.
• W2511396506 hasConceptScore W2511396506C181199279 @default.
• W2511396506 hasConceptScore W2511396506C203014093 @default.
• W2511396506 hasConceptScore W2511396506C2522874641 @default.

• next