Matches in SemOpenAlex for { <https://semopenalex.org/work/W2511455725> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- W2511455725 abstract "Natural tears contain water, sodium chloride and various other components like proteins, lipids, mucins, antioxidants and buffer substances. Tear substitutes which are used for therapy of the dry eye syndrome mostly lack natural tear components and ingredients with antioxidative potential. Thus, the aim of our study was to identify substances with protective function against ultraviolet (UV) light and ozone, which could be used in artificial tear substitutes. Viscosity measurements were perfomed using a 0.25% hyaluronic acid solution with a viscosity of 2.12 centi Stokes (cSt) [range 2.09 – 2.15], as well as extracts and substances with possible antioxidative effects after irradiation with ultraviolet light and ozone. UV light and ozone lead to a depolymerisation of hyaluronic acid associated with an decrease of viscosity to 1.76 cSt [range 1.56 – 1.87] and 1.46 cSt [range 1.41 – 1.63], respectively. Eleven substances with possible hyaluronic acid stabilizing effects were investigated. Eyebright (Euphrasia spp.) and mannitol could significantly protect hyaluronic acid from a degradation (p < 0.01). The viscosity was 2.05 cSt [range 2.04 – 2.05] and 2.07 cSt [range 2.05 – 2.08] through influence of UV light and ozone, respectively, with the protective components. Uric acid (1.76 cSt) and melatonine (1.75 cSt) were able to achieve a significant stabilizing effect of hyaluronic acid against ozone (p < 0.01), but not against UV light. Arginine, curcumin, fructose, urea, lysine, spermidine and taurine did not stabilize hyaluronic acid after UV and ozone stress." @default.
- W2511455725 created "2016-09-16" @default.
- W2511455725 creator A5019280087 @default.
- W2511455725 creator A5038542046 @default.
- W2511455725 creator A5043491712 @default.
- W2511455725 creator A5061138153 @default.
- W2511455725 creator A5077038677 @default.
- W2511455725 creator A5090807814 @default.
- W2511455725 date "2015-11-25" @default.
- W2511455725 modified "2023-10-18" @default.
- W2511455725 title "Euphrasia spp. as a natural stabilizer of hyaluronic acid – A step closer to physiological human tear fluids?" @default.
- W2511455725 doi "https://doi.org/10.1055/s-0035-1565504" @default.
- W2511455725 hasPublicationYear "2015" @default.
- W2511455725 type Work @default.
- W2511455725 sameAs 2511455725 @default.
- W2511455725 citedByCount "0" @default.
- W2511455725 crossrefType "journal-article" @default.
- W2511455725 hasAuthorship W2511455725A5019280087 @default.
- W2511455725 hasAuthorship W2511455725A5038542046 @default.
- W2511455725 hasAuthorship W2511455725A5043491712 @default.
- W2511455725 hasAuthorship W2511455725A5061138153 @default.
- W2511455725 hasAuthorship W2511455725A5077038677 @default.
- W2511455725 hasAuthorship W2511455725A5090807814 @default.
- W2511455725 hasConcept C105702510 @default.
- W2511455725 hasConcept C185592680 @default.
- W2511455725 hasConcept C2777529286 @default.
- W2511455725 hasConcept C31903555 @default.
- W2511455725 hasConcept C43617362 @default.
- W2511455725 hasConcept C55493867 @default.
- W2511455725 hasConcept C71924100 @default.
- W2511455725 hasConceptScore W2511455725C105702510 @default.
- W2511455725 hasConceptScore W2511455725C185592680 @default.
- W2511455725 hasConceptScore W2511455725C2777529286 @default.
- W2511455725 hasConceptScore W2511455725C31903555 @default.
- W2511455725 hasConceptScore W2511455725C43617362 @default.
- W2511455725 hasConceptScore W2511455725C55493867 @default.
- W2511455725 hasConceptScore W2511455725C71924100 @default.
- W2511455725 hasIssue "16" @default.
- W2511455725 hasLocation W25114557251 @default.
- W2511455725 hasOpenAccess W2511455725 @default.
- W2511455725 hasPrimaryLocation W25114557251 @default.
- W2511455725 hasRelatedWork W1498990732 @default.
- W2511455725 hasRelatedWork W1973023675 @default.
- W2511455725 hasRelatedWork W1977120912 @default.
- W2511455725 hasRelatedWork W1982188216 @default.
- W2511455725 hasRelatedWork W1997308825 @default.
- W2511455725 hasRelatedWork W2019825145 @default.
- W2511455725 hasRelatedWork W2042216829 @default.
- W2511455725 hasRelatedWork W2090553026 @default.
- W2511455725 hasRelatedWork W2180973289 @default.
- W2511455725 hasRelatedWork W2990360846 @default.
- W2511455725 hasVolume "81" @default.
- W2511455725 isParatext "false" @default.
- W2511455725 isRetracted "false" @default.
- W2511455725 magId "2511455725" @default.
- W2511455725 workType "article" @default.