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- W2511459610 abstract "Summary In 2003, the Fund for the Replacement of Animals in Medical Experiments (FRAME) revealed that the potency of botulinum toxin for use as a popular wrinkle treatment is assessed by using the LD50 Test. The endpoint in this mouse-based testing is death through suffocation. In 2004, The Humane Society of the United States (HSUS) sought to work with Allergan, the US-based manufacturer of Botox® Cosmetic, and the U.S. Food and Drug Administration (FDA), on ways to refine, reduce, and replace this LD50 testing. This article summarises The HSUS’s campaign in the United States and provides an update on FRAME’s continuing efforts in Europe." @default.
- W2511459610 created "2016-09-16" @default.
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- W2511459610 date "2005-01-01" @default.
- W2511459610 modified "2023-09-24" @default.
- W2511459610 title "LD50 Testing of Botulinum Toxin for Use as a Cosmetic" @default.
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