Matches in SemOpenAlex for { <https://semopenalex.org/work/W2511488302> ?p ?o ?g. }
- W2511488302 abstract "Colorectal cancer (CRC) is a multi-factorial disease, and genetic background may contribute to its etiology. Single nucleotide polymorphisms (SNPs) in microRNAs (miRNAs) may be used as specific markers of predisposition for CRC diagnosis and prevention. In this review, we summarize and discuss recent publications evaluating the roles of miRNA SNPs in CRC. A meta-analysis was also carried out to assess the association between the five most frequently studied miRNA SNPs and CRC risk. No relationship was established between this disease and the three SNPs rs11614913, rs2910164, and rs3746444 in miR-196a-2, miR-146a, and miR-499, respectively. However, polymorphisms of miR-149 (rs2292832; CT vs TT: odds ratio [OR] = 0.816, 95% confidence interval [CI] = 0.691-0.963; CC+CT vs TT: OR = 0.834, 95%CI = 0.715-0.972) and pre-miR-27a (rs895819; GG vs AA: OR = 1.534, 95%CI = 1.148-2.049; GG+AG vs AA: OR = 1.324, 95%CI = 1.066-1.645) were found to be associated with CRC in our analysis. In conclusion, the SNPs rs2292832 in miR-149 and rs895819 in pre-miR-27a were associated with CRC susceptibility, whereas rs11614913, rs2910164, and rs3746444 in miR-196a-2, miR-146a, and miR-499, respectively, were not. Further studies should be carried out to validate these findings." @default.
- W2511488302 created "2016-09-16" @default.
- W2511488302 creator A5005634192 @default.
- W2511488302 creator A5022444278 @default.
- W2511488302 creator A5029701527 @default.
- W2511488302 creator A5046407339 @default.
- W2511488302 creator A5058413567 @default.
- W2511488302 creator A5069860538 @default.
- W2511488302 creator A5072602840 @default.
- W2511488302 date "2016-01-01" @default.
- W2511488302 modified "2023-10-17" @default.
- W2511488302 title "MicroRNA variants and colorectal cancer risk: a meta-analysis" @default.
- W2511488302 cites W1441212380 @default.
- W2511488302 cites W1481308183 @default.
- W2511488302 cites W1562704323 @default.
- W2511488302 cites W1604117402 @default.
- W2511488302 cites W182821515 @default.
- W2511488302 cites W1963965211 @default.
- W2511488302 cites W1964724521 @default.
- W2511488302 cites W1971460830 @default.
- W2511488302 cites W1972511235 @default.
- W2511488302 cites W1972987358 @default.
- W2511488302 cites W1975541179 @default.
- W2511488302 cites W1980957875 @default.
- W2511488302 cites W1988988041 @default.
- W2511488302 cites W1994107017 @default.
- W2511488302 cites W2025336695 @default.
- W2511488302 cites W2027477052 @default.
- W2511488302 cites W2028010222 @default.
- W2511488302 cites W2035033138 @default.
- W2511488302 cites W2043252604 @default.
- W2511488302 cites W2044967196 @default.
- W2511488302 cites W2051278243 @default.
- W2511488302 cites W2052567908 @default.
- W2511488302 cites W2057318887 @default.
- W2511488302 cites W2057582374 @default.
- W2511488302 cites W2096812786 @default.
- W2511488302 cites W2100364067 @default.
- W2511488302 cites W2106613615 @default.
- W2511488302 cites W2106787323 @default.
- W2511488302 cites W2109975638 @default.
- W2511488302 cites W2139389450 @default.
- W2511488302 cites W2144926985 @default.
- W2511488302 cites W2149034684 @default.
- W2511488302 cites W2159006082 @default.
- W2511488302 cites W2167043533 @default.
- W2511488302 cites W2167350847 @default.
- W2511488302 cites W2168344812 @default.
- W2511488302 cites W2170932064 @default.
- W2511488302 cites W2282481768 @default.
- W2511488302 cites W2339783227 @default.
- W2511488302 cites W247771779 @default.
- W2511488302 doi "https://doi.org/10.4238/gmr.15038478" @default.
- W2511488302 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27706637" @default.
- W2511488302 hasPublicationYear "2016" @default.
- W2511488302 type Work @default.
- W2511488302 sameAs 2511488302 @default.
- W2511488302 citedByCount "15" @default.
- W2511488302 countsByYear W25114883022017 @default.
- W2511488302 countsByYear W25114883022018 @default.
- W2511488302 countsByYear W25114883022020 @default.
- W2511488302 countsByYear W25114883022021 @default.
- W2511488302 countsByYear W25114883022022 @default.
- W2511488302 countsByYear W25114883022023 @default.
- W2511488302 crossrefType "journal-article" @default.
- W2511488302 hasAuthorship W2511488302A5005634192 @default.
- W2511488302 hasAuthorship W2511488302A5022444278 @default.
- W2511488302 hasAuthorship W2511488302A5029701527 @default.
- W2511488302 hasAuthorship W2511488302A5046407339 @default.
- W2511488302 hasAuthorship W2511488302A5058413567 @default.
- W2511488302 hasAuthorship W2511488302A5069860538 @default.
- W2511488302 hasAuthorship W2511488302A5072602840 @default.
- W2511488302 hasBestOaLocation W25114883021 @default.
- W2511488302 hasConcept C104317684 @default.
- W2511488302 hasConcept C121608353 @default.
- W2511488302 hasConcept C126322002 @default.
- W2511488302 hasConcept C135763542 @default.
- W2511488302 hasConcept C143998085 @default.
- W2511488302 hasConcept C145059251 @default.
- W2511488302 hasConcept C153209595 @default.
- W2511488302 hasConcept C156957248 @default.
- W2511488302 hasConcept C2779134260 @default.
- W2511488302 hasConcept C2992519594 @default.
- W2511488302 hasConcept C44249647 @default.
- W2511488302 hasConcept C526805850 @default.
- W2511488302 hasConcept C54355233 @default.
- W2511488302 hasConcept C60644358 @default.
- W2511488302 hasConcept C67636389 @default.
- W2511488302 hasConcept C71924100 @default.
- W2511488302 hasConcept C86803240 @default.
- W2511488302 hasConcept C95190672 @default.
- W2511488302 hasConceptScore W2511488302C104317684 @default.
- W2511488302 hasConceptScore W2511488302C121608353 @default.
- W2511488302 hasConceptScore W2511488302C126322002 @default.
- W2511488302 hasConceptScore W2511488302C135763542 @default.
- W2511488302 hasConceptScore W2511488302C143998085 @default.
- W2511488302 hasConceptScore W2511488302C145059251 @default.
- W2511488302 hasConceptScore W2511488302C153209595 @default.
- W2511488302 hasConceptScore W2511488302C156957248 @default.
- W2511488302 hasConceptScore W2511488302C2779134260 @default.