FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2511494266> ?p ?o ?g. }

• W2511494266 endingPage "92" @default.
• W2511494266 startingPage "85" @default.
• W2511494266 abstract "BackgroundZinc is an essential micronutrient for humans with important physiological functions. A sensitive and specific biomarker for assessing Zn status is still needed.ObjectiveThe major aim of this study was to examine if the changes in the content of plasma phospholipid LA, DGLA and LA: DGLA ratio can be used to efficiently predict the dietary Zn intake and plasma Zn status of humans.MethodsThe study was performed on healthy human volunteers, 25–55 years of age. The dietary Zn intake was assessed using 24 h recall questionnaires. Plasma phospholipid fatty acid analysis was done by gas chromatography, and plasma analysis of minerals by atomic absorption spectrometry. Biochemical, anthropometrical and hematological parameters were assessed.ResultsNo significant relationship was found between the dietary and plasma zinc status (r = 0.07; p = 0.6). There was a statistically significant correlation between DGLA and plasma Zn (r = 0.39, p = 0.00). No relationship was observed between the linoleic acid and plasma Zn, while there was a significant negative correlation between LA: DGLA ratio and plasma Zn status (r = −0.35, p = 0.01). Similarly, there were statistically significant difference in DGLA status (p = 0.004) and LA: DGLA ratio (p = 0.042) between the Zn formed groups.ConclusionsThis study is an initial step in evaluating LA: DGLA ratio as a biomarker of Zn status in humans. The results are encouraging as they show that concentration of DGLA is decreased and LA: DGLA ratio increased in people with lower dietary Zn intake. However, additional studies are needed to fully examine the sensitivity of this biomarker. Zinc is an essential micronutrient for humans with important physiological functions. A sensitive and specific biomarker for assessing Zn status is still needed. The major aim of this study was to examine if the changes in the content of plasma phospholipid LA, DGLA and LA: DGLA ratio can be used to efficiently predict the dietary Zn intake and plasma Zn status of humans. The study was performed on healthy human volunteers, 25–55 years of age. The dietary Zn intake was assessed using 24 h recall questionnaires. Plasma phospholipid fatty acid analysis was done by gas chromatography, and plasma analysis of minerals by atomic absorption spectrometry. Biochemical, anthropometrical and hematological parameters were assessed. No significant relationship was found between the dietary and plasma zinc status (r = 0.07; p = 0.6). There was a statistically significant correlation between DGLA and plasma Zn (r = 0.39, p = 0.00). No relationship was observed between the linoleic acid and plasma Zn, while there was a significant negative correlation between LA: DGLA ratio and plasma Zn status (r = −0.35, p = 0.01). Similarly, there were statistically significant difference in DGLA status (p = 0.004) and LA: DGLA ratio (p = 0.042) between the Zn formed groups. This study is an initial step in evaluating LA: DGLA ratio as a biomarker of Zn status in humans. The results are encouraging as they show that concentration of DGLA is decreased and LA: DGLA ratio increased in people with lower dietary Zn intake. However, additional studies are needed to fully examine the sensitivity of this biomarker." @default.
• W2511494266 created "2016-09-16" @default.
• W2511494266 creator A5022139095 @default.
• W2511494266 creator A5023900741 @default.
• W2511494266 creator A5034508665 @default.
• W2511494266 creator A5034761926 @default.
• W2511494266 creator A5060240842 @default.
• W2511494266 creator A5065243407 @default.
• W2511494266 creator A5066797277 @default.
• W2511494266 date "2016-10-01" @default.
• W2511494266 modified "2023-09-29" @default.
• W2511494266 title "An initial evaluation of newly proposed biomarker of zinc status in humans - linoleic acid: dihomo-γ-linolenic acid (LA:DGLA) ratio" @default.
• W2511494266 cites W1884233186 @default.
• W2511494266 cites W1964527917 @default.
• W2511494266 cites W1965945511 @default.
• W2511494266 cites W1972441901 @default.
• W2511494266 cites W1972832086 @default.
• W2511494266 cites W1974465341 @default.
• W2511494266 cites W1974789908 @default.
• W2511494266 cites W1974820916 @default.
• W2511494266 cites W1977877910 @default.
• W2511494266 cites W1978130328 @default.
• W2511494266 cites W1982553013 @default.
• W2511494266 cites W1984513006 @default.
• W2511494266 cites W1996305946 @default.
• W2511494266 cites W2001110434 @default.
• W2511494266 cites W2002991824 @default.
• W2511494266 cites W2003347868 @default.
• W2511494266 cites W2010951977 @default.
• W2511494266 cites W2012747552 @default.
• W2511494266 cites W2013308489 @default.
• W2511494266 cites W2013617066 @default.
• W2511494266 cites W2029485505 @default.
• W2511494266 cites W2029558262 @default.
• W2511494266 cites W2031720531 @default.
• W2511494266 cites W2035152851 @default.
• W2511494266 cites W2048860233 @default.
• W2511494266 cites W2059144268 @default.
• W2511494266 cites W2062765507 @default.
• W2511494266 cites W2063958751 @default.
• W2511494266 cites W2071321331 @default.
• W2511494266 cites W2071658446 @default.
• W2511494266 cites W2076162655 @default.
• W2511494266 cites W2082646293 @default.
• W2511494266 cites W2088805278 @default.
• W2511494266 cites W2094505735 @default.
• W2511494266 cites W2099279841 @default.
• W2511494266 cites W2102936024 @default.
• W2511494266 cites W2104552193 @default.
• W2511494266 cites W2110745296 @default.
• W2511494266 cites W2112371221 @default.
• W2511494266 cites W2120774445 @default.
• W2511494266 cites W2125803750 @default.
• W2511494266 cites W2131656180 @default.
• W2511494266 cites W2134874782 @default.
• W2511494266 cites W2135803061 @default.
• W2511494266 cites W2142145496 @default.
• W2511494266 cites W2142802289 @default.
• W2511494266 cites W2151028417 @default.
• W2511494266 cites W2253646582 @default.
• W2511494266 cites W2609433706 @default.
• W2511494266 doi "https://doi.org/10.1016/j.clnesp.2016.06.013" @default.
• W2511494266 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28531790" @default.
• W2511494266 hasPublicationYear "2016" @default.
• W2511494266 type Work @default.
• W2511494266 sameAs 2511494266 @default.
• W2511494266 citedByCount "31" @default.
• W2511494266 countsByYear W25114942662017 @default.
• W2511494266 countsByYear W25114942662018 @default.
• W2511494266 countsByYear W25114942662019 @default.
• W2511494266 countsByYear W25114942662020 @default.
• W2511494266 countsByYear W25114942662021 @default.
• W2511494266 countsByYear W25114942662022 @default.
• W2511494266 countsByYear W25114942662023 @default.
• W2511494266 crossrefType "journal-article" @default.
• W2511494266 hasAuthorship W2511494266A5022139095 @default.
• W2511494266 hasAuthorship W2511494266A5023900741 @default.
• W2511494266 hasAuthorship W2511494266A5034508665 @default.
• W2511494266 hasAuthorship W2511494266A5034761926 @default.
• W2511494266 hasAuthorship W2511494266A5060240842 @default.
• W2511494266 hasAuthorship W2511494266A5065243407 @default.
• W2511494266 hasAuthorship W2511494266A5066797277 @default.
• W2511494266 hasBestOaLocation W25114942661 @default.
• W2511494266 hasConcept C126322002 @default.
• W2511494266 hasConcept C134018914 @default.
• W2511494266 hasConcept C142724271 @default.
• W2511494266 hasConcept C14522933 @default.
• W2511494266 hasConcept C178790620 @default.
• W2511494266 hasConcept C185592680 @default.
• W2511494266 hasConcept C2780809830 @default.
• W2511494266 hasConcept C2781197716 @default.
• W2511494266 hasConcept C535196362 @default.
• W2511494266 hasConcept C543025807 @default.
• W2511494266 hasConcept C55493867 @default.
• W2511494266 hasConcept C71924100 @default.
• W2511494266 hasConceptScore W2511494266C126322002 @default.
• W2511494266 hasConceptScore W2511494266C134018914 @default.
• W2511494266 hasConceptScore W2511494266C142724271 @default.

• next