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• W2511500908 abstract "2-(Trifluoromethyl)furanones were obtained in good yields via the Claisen condensation of acetophenones with methyl 2-methoxytetrafluoropropionate, followed by sulfuric acid-mediated deprotection of the reaction products. These compounds react with 2,3-diaminopyridine, o-phenylenediamine and 2,3-diaminonaphthalene in refluxing acetic acid to give the corresponding quinoxaline derivatives, the regioisomeric and tautomeric composition of which was investigated. Reactions of 2-(trifluoromethyl)furanones with hydrazines and hydroxylamine proceeded regioselectively and gave pyridazine, pyrazole and isoxazole derivatives in high yields. Their regiochemistry was established by X-ray diffraction analysis." @default.
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• W2511500908 date "2015-11-01" @default.
• W2511500908 modified "2023-10-02" @default.
• W2511500908 title "Synthesis of 5-aryl-2-hydroxy-2-(trifluoromethyl)furan-3(2H)-ones and their reactions with aromatic 1,2-diamines, hydrazine and hydroxylamine" @default.
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• W2511500908 doi "https://doi.org/10.1016/j.tet.2015.09.035" @default.
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