FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2511752182> ?p ?o ?g. }

• W2511752182 endingPage "643" @default.
• W2511752182 startingPage "635" @default.
• W2511752182 abstract "Background: Risk factors related to renal function decline in type 2 diabetes mellitus (T2DM) remain uncertain. This study aimed to investigate risk factors in relation to renal function decline in patients with T2DM and in a subgroup of patients with normoalbuminuria. Methods: This study was a retrospective cohort study, which included 451 patients with T2DM aged 63 ± 14 years admitted to a tertiary hospital in Beijing, China, between April and December 2010 and followed up for 6–60 months. Endpoint was renal function decline, defined as estimated glomerular filtration rate less than 60 mL/min 1.73 m2 or at least twofold increase of serum creatinine. Cox proportional hazards analysis was used to estimate hazard ratios (HRs) for candidate risk factors of renal function decline. Results: After a median follow-up of 3.3 years, 94 (20.8%) patients developed renal function decline. Increased age (HR, 1.045; 95% CI, 1.020–1.070), albuminuria (HR, 1.956; 95%CI, 1.271–3.011), mild renal dysfunction (HR, 4.521; 95%CI, 2.734–7.476), hyperfiltration (HR, 3.897; 95%CI, 1.572–9.663), and increased hemoglobin A1c (HR, 1.128; 95%CI, 1.020–1.249) were identified as major risk factors. Among a subgroup of 344 patients with normoalbuminuria at baseline, 53 (15.4%) patients developed renal function decline. Increased age (HR, 1.089; 95%CI, 1.050–1.129), mild renal dysfunction (HR, 4.667; 95%CI, 2.391–9.107), hyperfiltration (HR, 5.677; 95%CI, 1.544–20.872), smoking (HR, 2.886; 95%CI, 1.370–6.082), higher pulse pressure (HR, 1.022; 95%CI, 1.004–1.040), and increased fasting glucose (HR, 1.104; 95%CI, 1.020–1.194) were major risk factors. Conclusions: Risk factors of diabetic renal impairment in T2DM should be screened and evaluated at an early stage of diabetes. Albuminuria, mild renal dysfunction, hyperfiltration, increased blood glucose, increased pulse pressure, and smoking were all predictors for diabetic renal impairment and interventions that focus on these risk factors may reduce further decline in renal function." @default.
• W2511752182 created "2016-09-16" @default.
• W2511752182 creator A5025443120 @default.
• W2511752182 creator A5035164138 @default.
• W2511752182 creator A5046517816 @default.
• W2511752182 creator A5075388616 @default.
• W2511752182 date "2016-10-01" @default.
• W2511752182 modified "2023-10-16" @default.
• W2511752182 title "Predictors of Renal Function Decline in Chinese Patients with Type 2 Diabetes Mellitus and in a Subgroup of Normoalbuminuria: A Retrospective Cohort Study" @default.
• W2511752182 cites W1523778995 @default.
• W2511752182 cites W1526927233 @default.
• W2511752182 cites W1707125164 @default.
• W2511752182 cites W1845526741 @default.
• W2511752182 cites W1965860996 @default.
• W2511752182 cites W1981998568 @default.
• W2511752182 cites W1984061204 @default.
• W2511752182 cites W1985105696 @default.
• W2511752182 cites W1986025060 @default.
• W2511752182 cites W1986440652 @default.
• W2511752182 cites W1991653577 @default.
• W2511752182 cites W2012766272 @default.
• W2511752182 cites W2015389899 @default.
• W2511752182 cites W2017574249 @default.
• W2511752182 cites W2028574541 @default.
• W2511752182 cites W2028855276 @default.
• W2511752182 cites W2039719471 @default.
• W2511752182 cites W2041550338 @default.
• W2511752182 cites W2044773944 @default.
• W2511752182 cites W2050826908 @default.
• W2511752182 cites W2051240093 @default.
• W2511752182 cites W2053585216 @default.
• W2511752182 cites W2056267318 @default.
• W2511752182 cites W2056976690 @default.
• W2511752182 cites W2090811314 @default.
• W2511752182 cites W2096040474 @default.
• W2511752182 cites W2096767780 @default.
• W2511752182 cites W2105028010 @default.
• W2511752182 cites W2105582298 @default.
• W2511752182 cites W2107412805 @default.
• W2511752182 cites W2111478784 @default.
• W2511752182 cites W2113285066 @default.
• W2511752182 cites W2116404316 @default.
• W2511752182 cites W2117168880 @default.
• W2511752182 cites W2123893097 @default.
• W2511752182 cites W2130561540 @default.
• W2511752182 cites W2132647859 @default.
• W2511752182 cites W2132846857 @default.
• W2511752182 cites W2133507189 @default.
• W2511752182 cites W2138829643 @default.
• W2511752182 cites W2140293934 @default.
• W2511752182 cites W2142203999 @default.
• W2511752182 cites W2147994802 @default.
• W2511752182 cites W2151100203 @default.
• W2511752182 cites W2155965977 @default.
• W2511752182 cites W2159511512 @default.
• W2511752182 cites W2159760627 @default.
• W2511752182 cites W364216528 @default.
• W2511752182 cites W4211025575 @default.
• W2511752182 cites W4245485459 @default.
• W2511752182 doi "https://doi.org/10.1089/dia.2016.0115" @default.
• W2511752182 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27583456" @default.
• W2511752182 hasPublicationYear "2016" @default.
• W2511752182 type Work @default.
• W2511752182 sameAs 2511752182 @default.
• W2511752182 citedByCount "4" @default.
• W2511752182 countsByYear W25117521822019 @default.
• W2511752182 countsByYear W25117521822020 @default.
• W2511752182 countsByYear W25117521822022 @default.
• W2511752182 countsByYear W25117521822023 @default.
• W2511752182 crossrefType "journal-article" @default.
• W2511752182 hasAuthorship W2511752182A5025443120 @default.
• W2511752182 hasAuthorship W2511752182A5035164138 @default.
• W2511752182 hasAuthorship W2511752182A5046517816 @default.
• W2511752182 hasAuthorship W2511752182A5075388616 @default.
• W2511752182 hasConcept C126322002 @default.
• W2511752182 hasConcept C134018914 @default.
• W2511752182 hasConcept C159641895 @default.
• W2511752182 hasConcept C167135981 @default.
• W2511752182 hasConcept C187960798 @default.
• W2511752182 hasConcept C201903717 @default.
• W2511752182 hasConcept C207103383 @default.
• W2511752182 hasConcept C2780306776 @default.
• W2511752182 hasConcept C2910068830 @default.
• W2511752182 hasConcept C44249647 @default.
• W2511752182 hasConcept C50382708 @default.
• W2511752182 hasConcept C555293320 @default.
• W2511752182 hasConcept C71924100 @default.
• W2511752182 hasConcept C72563966 @default.
• W2511752182 hasConceptScore W2511752182C126322002 @default.
• W2511752182 hasConceptScore W2511752182C134018914 @default.
• W2511752182 hasConceptScore W2511752182C159641895 @default.
• W2511752182 hasConceptScore W2511752182C167135981 @default.
• W2511752182 hasConceptScore W2511752182C187960798 @default.
• W2511752182 hasConceptScore W2511752182C201903717 @default.
• W2511752182 hasConceptScore W2511752182C207103383 @default.
• W2511752182 hasConceptScore W2511752182C2780306776 @default.
• W2511752182 hasConceptScore W2511752182C2910068830 @default.
• W2511752182 hasConceptScore W2511752182C44249647 @default.

• next