Matches in SemOpenAlex for { <https://semopenalex.org/work/W2511765556> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2511765556 endingPage "514" @default.
- W2511765556 startingPage "510" @default.
- W2511765556 abstract "To report the evolution of patients with a suggestive clinical scenario and elevated serum insulin-like growth factor-1 (IGF-1), but growth hormone (GH) suppression in the oral glucose tolerance test (OGTT), in whom acromegaly was not initially excluded.Forty six patients with a suggestive clinical scenario, who had elevated IGF-1 (outside puberty and pregnancy) in two measurements, but GH < 0.4 µg/L in the OGTT, were selected. Five years after initial evaluation, the patients were submitted to clinical and laboratory (serum IGF-1) reassessment. Patients with persistently elevated IGF-1 were submitted to a new GH suppression test and magnetic resonance imaging (MRI) of the pituitary.Four patients were lost to follow-up. During reassessment, 42 patients continued to show no typical phenotype or changes in physiognomy. Fifteen of the 42 patients had normal IGF-1. Among the 27 patients with persistently elevated IGF-1 and who were submitted to a new OGTT, GH suppression was confirmed in all. Two patients exhibited a lesion suggestive of microadenoma on pituitary MRI. In our interpretation of the results, acromegaly was ruled out in 40 patients and considered possible in only 2.Our results show that even in patients with a suggestive clinical scenario and elevated IGF-1, confirmed in a second measurement and without apparent cause, acromegaly is very unlikely in the case of GH suppression in the OGTT." @default.
- W2511765556 created "2016-09-16" @default.
- W2511765556 creator A5066463606 @default.
- W2511765556 creator A5081595342 @default.
- W2511765556 date "2016-12-01" @default.
- W2511765556 modified "2023-10-17" @default.
- W2511765556 title "Elevated IGF-1 with GH suppression after an oral glucose overload: incipient acromegaly or false-positive IGF-1?" @default.
- W2511765556 cites W1982853378 @default.
- W2511765556 cites W1993742570 @default.
- W2511765556 cites W1994795197 @default.
- W2511765556 cites W1998519715 @default.
- W2511765556 cites W2002468003 @default.
- W2511765556 cites W2020982698 @default.
- W2511765556 cites W2026587504 @default.
- W2511765556 cites W2029803616 @default.
- W2511765556 cites W2038222189 @default.
- W2511765556 cites W2040492170 @default.
- W2511765556 cites W2045814432 @default.
- W2511765556 cites W2062734040 @default.
- W2511765556 cites W2064532834 @default.
- W2511765556 cites W2067299067 @default.
- W2511765556 cites W2072531409 @default.
- W2511765556 cites W2087689997 @default.
- W2511765556 cites W2095591038 @default.
- W2511765556 cites W2098717833 @default.
- W2511765556 cites W2100456193 @default.
- W2511765556 cites W2112907533 @default.
- W2511765556 cites W2135450307 @default.
- W2511765556 cites W2141622160 @default.
- W2511765556 cites W2155465275 @default.
- W2511765556 cites W3212738990 @default.
- W2511765556 cites W98681037 @default.
- W2511765556 doi "https://doi.org/10.1590/2359-3997000000193" @default.
- W2511765556 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27982199" @default.
- W2511765556 hasPublicationYear "2016" @default.
- W2511765556 type Work @default.
- W2511765556 sameAs 2511765556 @default.
- W2511765556 citedByCount "5" @default.
- W2511765556 countsByYear W25117655562016 @default.
- W2511765556 countsByYear W25117655562021 @default.
- W2511765556 countsByYear W25117655562022 @default.
- W2511765556 crossrefType "journal-article" @default.
- W2511765556 hasAuthorship W2511765556A5066463606 @default.
- W2511765556 hasAuthorship W2511765556A5081595342 @default.
- W2511765556 hasBestOaLocation W25117655561 @default.
- W2511765556 hasConcept C126322002 @default.
- W2511765556 hasConcept C126838900 @default.
- W2511765556 hasConcept C134018914 @default.
- W2511765556 hasConcept C142724271 @default.
- W2511765556 hasConcept C143409427 @default.
- W2511765556 hasConcept C2777391703 @default.
- W2511765556 hasConcept C2777433750 @default.
- W2511765556 hasConcept C2779113265 @default.
- W2511765556 hasConcept C2779306644 @default.
- W2511765556 hasConcept C2781156865 @default.
- W2511765556 hasConcept C2984496839 @default.
- W2511765556 hasConcept C3017594256 @default.
- W2511765556 hasConcept C71315377 @default.
- W2511765556 hasConcept C71924100 @default.
- W2511765556 hasConceptScore W2511765556C126322002 @default.
- W2511765556 hasConceptScore W2511765556C126838900 @default.
- W2511765556 hasConceptScore W2511765556C134018914 @default.
- W2511765556 hasConceptScore W2511765556C142724271 @default.
- W2511765556 hasConceptScore W2511765556C143409427 @default.
- W2511765556 hasConceptScore W2511765556C2777391703 @default.
- W2511765556 hasConceptScore W2511765556C2777433750 @default.
- W2511765556 hasConceptScore W2511765556C2779113265 @default.
- W2511765556 hasConceptScore W2511765556C2779306644 @default.
- W2511765556 hasConceptScore W2511765556C2781156865 @default.
- W2511765556 hasConceptScore W2511765556C2984496839 @default.
- W2511765556 hasConceptScore W2511765556C3017594256 @default.
- W2511765556 hasConceptScore W2511765556C71315377 @default.
- W2511765556 hasConceptScore W2511765556C71924100 @default.
- W2511765556 hasIssue "6" @default.
- W2511765556 hasLocation W25117655561 @default.
- W2511765556 hasLocation W25117655562 @default.
- W2511765556 hasLocation W25117655563 @default.
- W2511765556 hasOpenAccess W2511765556 @default.
- W2511765556 hasPrimaryLocation W25117655561 @default.
- W2511765556 hasRelatedWork W1972336819 @default.
- W2511765556 hasRelatedWork W2010293264 @default.
- W2511765556 hasRelatedWork W2021502319 @default.
- W2511765556 hasRelatedWork W2037601963 @default.
- W2511765556 hasRelatedWork W2063463512 @default.
- W2511765556 hasRelatedWork W2066922718 @default.
- W2511765556 hasRelatedWork W2079613337 @default.
- W2511765556 hasRelatedWork W2122674805 @default.
- W2511765556 hasRelatedWork W2168692948 @default.
- W2511765556 hasRelatedWork W2182635640 @default.
- W2511765556 hasVolume "60" @default.
- W2511765556 isParatext "false" @default.
- W2511765556 isRetracted "false" @default.
- W2511765556 magId "2511765556" @default.
- W2511765556 workType "article" @default.