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- W2511789529 abstract "Background: Meningiomas are slow growing extra-axial tumors originated from arachnoid. Although they are usually benign, early diagnosis is difficult due to lack of clinical manifestations in the beginning of disease. Actually, sometimes the only symptom is psychiatric disorders. Objective: Present and discuss a case from Santa Mônica Hospital, in Goiânia-GO, Brazil, of meningioma that also had thrombotic events. Patient and methods: Man, 48 years, began with behavior changes and aggressivity in the past year and was diagnosed as a cognitive disorder and emotional lability, and medicated with risperidone. 40 days ago he was admitted to the neurosurgery service because of paraparesis, although some new symptoms had also appeared: visual acuity reduction, intermittent headache, anosmia. CT revealed volumous meningioma in anterior fossa (6,3x6,2x2,8 cm) with midline shift, compressive effects of parenchyma and ventricular system. Emergency ventriculoperitoneal shunt was performed, and surgical tumor resection was postponed due to acute thrombosis of soleal, posterior tibial, fibular veins of both inferior limbs in post operative. Results: It is largely known that compression of frontal lobes by meningiomas may have different presentations, including psychiatric just as it happened in this case. Another event that occurred in this case, and is frequently associated with cancer, was the deep vein thrombosis, which happens because of procoagulant factors synthesis by tumoral cells. Actually, neoplams are one of the most important independent risk factors for thrombotic events. Conclusion: There were two northern axes for this report: psychiatric manifestations for frontal meningiomas, and thrombotic events associated with tumours." @default.
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- W2511789529 date "2015-10-01" @default.
- W2511789529 modified "2023-09-26" @default.
- W2511789529 title "Meningioma case report with psychiatric presentation, evolving with thrombotic events" @default.
- W2511789529 doi "https://doi.org/10.1016/j.jns.2015.08.632" @default.
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