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- W2512452308 abstract "Materials In the group of 6 patients, who have initially been treated with radical surgery by Miles method because of rectal cancer followed by EBRT and who were afterwards diagnosed with locally advanced prostate cancer, the brachytherapy for prostate cancer has been performed. Methods The fractionated interstitial brachytherapy was applied in the regimen: 3 times a 12 Gy in an interval of 21 days. Computed tomography (CT) has been used to localize the prostate, applicators and for acquisition to the planning system. Due to mobility of the prostate depending on the position of the body, patients were positioned on the side and individually adjusted for each application. The spinal anesthesia was delivered. Initial, pre-implantation CT allowed to locate the prostate, bladder and bone structures. CT scans were repeated after insertion of the next 3 needles for accuracy reasons. After the placement of applicators, final CT scanning was performed for the implementation to the treatment planning system Oncentra MasterPlan Brachy 4.1 Results HDR Brachytherapy treatment planning for prostate cancer with the use of CT-based planning software allowed to cover the prostate with the V100% isodose in the range of 87–98% (median 91%). Urethra hasn‘t been visible sufficiently in 2 first cases. After the use of iodinated contrast to fill-up the Foley catheter balloon in other four cases the course of the urethra was defined without doubts. The visibility of the bladder walls was in all cases poor due to Foley catheter insertion and the lack of urine in the bladder. Conclusions HDR Brachytherapy treatment planning for prostate cancer with the use of CT-based planning software Oncentra Brachy 4.1 allows to treat selected patients without rectal access. Planning optimization allows to meet ICRU criteria. The use of CT-based HDR brachytherapy planning system should be recommended for patients with locally advanced prostate cancer and the lack of rectum due to earlier operations as the method sufficient in its accuracy and relatively not expensive. In the group of 6 patients, who have initially been treated with radical surgery by Miles method because of rectal cancer followed by EBRT and who were afterwards diagnosed with locally advanced prostate cancer, the brachytherapy for prostate cancer has been performed. The fractionated interstitial brachytherapy was applied in the regimen: 3 times a 12 Gy in an interval of 21 days. Computed tomography (CT) has been used to localize the prostate, applicators and for acquisition to the planning system. Due to mobility of the prostate depending on the position of the body, patients were positioned on the side and individually adjusted for each application. The spinal anesthesia was delivered. Initial, pre-implantation CT allowed to locate the prostate, bladder and bone structures. CT scans were repeated after insertion of the next 3 needles for accuracy reasons. After the placement of applicators, final CT scanning was performed for the implementation to the treatment planning system Oncentra MasterPlan Brachy 4.1 HDR Brachytherapy treatment planning for prostate cancer with the use of CT-based planning software allowed to cover the prostate with the V100% isodose in the range of 87–98% (median 91%). Urethra hasn‘t been visible sufficiently in 2 first cases. After the use of iodinated contrast to fill-up the Foley catheter balloon in other four cases the course of the urethra was defined without doubts. The visibility of the bladder walls was in all cases poor due to Foley catheter insertion and the lack of urine in the bladder. HDR Brachytherapy treatment planning for prostate cancer with the use of CT-based planning software Oncentra Brachy 4.1 allows to treat selected patients without rectal access. Planning optimization allows to meet ICRU criteria. The use of CT-based HDR brachytherapy planning system should be recommended for patients with locally advanced prostate cancer and the lack of rectum due to earlier operations as the method sufficient in its accuracy and relatively not expensive." @default.
- W2512452308 created "2016-09-16" @default.
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- W2512452308 date "2016-09-01" @default.
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- W2512452308 title "Brachytherapy treatment planning for prostate cancer with the use of the computed tomography-based (CT-based) planning software in patients after total primary amputation of the rectum and EBRT (External Beam Radiation Therapy) due to rectal cancer" @default.
- W2512452308 doi "https://doi.org/10.1016/j.ejmp.2016.07.468" @default.
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