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• W2512821830 endingPage "38" @default.
• W2512821830 startingPage "29" @default.
• W2512821830 abstract "The pathogenesis of infectious agents with human tropism can only be properly studied in an in vivo model featuring human cells or tissue. Humanized mice represent a small animal model featuring human cells or tissue that can be infected by human-specific viruses, bacteria, and parasites and also providing a functional human immune system. This makes the analysis of a human immune response to infection possible and allows for preclinical testing of new vaccines and therapeutic agents. Results of various studies using humanized mice to investigate pathogens with human tropism are presented in this review. In addition, the limitations of humanized mice and methods to improve this valuable animal model are discussed." @default.
• W2512821830 created "2016-09-16" @default.
• W2512821830 creator A5079273157 @default.
• W2512821830 date "2016-12-01" @default.
• W2512821830 modified "2023-10-14" @default.
• W2512821830 title "Humanized mice in infectious diseases" @default.
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