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- W2512921054 abstract "Background: Staphylococcus aureus (S. aureus) is one of the earliest bacteria detected in infants and children with cystic fibrosis (CF). The rise of methicillin resistant S. aureus (MRSA) in the last 10 years has caused a lot of attention to this organism. Results: The aim of this review is to provide a general overview of methicillin sensitive S. aureus (MSSA) and MRSA, discuss special aspects of S. aureusincysticfibrosis,andtoreviewtreatmentconcepts.Microbiologyoftheorganismwillbereviewedalongwithdataregardingtheepidemiologyof bothMSSAandMRSA.AntibiotictreatmentsbothinregardstoacutemanagementanderadicationofMSSAandMRSAwillbereviewed.Prophylaxis of MSSA in CF remains controversial.Treatment with anti-staphylococcal agents reduces the infection rate with MSSA but may lead to a higherrate of infection with P. aeruginosa. In regards to MRSA, there is a paucity of clinical data regarding approaches to eradication. Conclusions: To advance the care of CF patients, controlled clinical trials are urgently needed to find the optimal approach to treating CF patients who are infected with either MSSA or MRSA." @default.
- W2512921054 created "2016-09-16" @default.
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- W2512921054 date "2011-01-01" @default.
- W2512921054 modified "2023-09-26" @default.
- W2512921054 title "Review Review: Staphylococcus aureus and MRSA in cystic fibrosis ☆" @default.
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