FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2512954480> ?p ?o ?g. }

• W2512954480 abstract "Head and neck squamous cell carcinoma (HNSCC) has become one of the most common forms of cancer worldwide. Hypermethylation-induced silencing of tumor-associated gene has been proposed as an important cofactor in cancer pathology. This paper aimed to characterize the gene methylation patterns in human papillomavirus (HPV) associated-HNSCC. TIMP3 and APC methylation status in neoplastic (N = 92) and non-neoplastic tissues (N = 92) of HNSCC as well as their association with HPV infection were investigated via methylation-specific PCR assays. Results indicated that methylation level of TIMP3 was markedly higher in HPV-positive tumors as compared with HPV-negative tumors. Both TIMP3 and APC methylation were associated with lymph node metastasis and higher clinical stage of tumors. Patients with methylation at TIMP3 or APC had worse prognoses as compared to those without these alterations. This is the first study that shows a possible linkage between HPV infection and APC methylation. Methylation patterns of tumor-related genes may contribute to different disease prognosis in HNSCC according to the HPV infection status." @default.
• W2512954480 created "2016-09-16" @default.
• W2512954480 creator A5026111824 @default.
• W2512954480 creator A5027882467 @default.
• W2512954480 creator A5060028133 @default.
• W2512954480 creator A5066323748 @default.
• W2512954480 date "2016-01-01" @default.
• W2512954480 modified "2023-09-26" @default.
• W2512954480 title "Characterization of gene methylation in human papillomavirus associated-head and neck squamous cell carcinoma" @default.
• W2512954480 cites W1568432012 @default.
• W2512954480 cites W1633962291 @default.
• W2512954480 cites W1658127082 @default.
• W2512954480 cites W1786325042 @default.
• W2512954480 cites W1964833190 @default.
• W2512954480 cites W1964901367 @default.
• W2512954480 cites W1966204215 @default.
• W2512954480 cites W1966538596 @default.
• W2512954480 cites W1976317724 @default.
• W2512954480 cites W1980156639 @default.
• W2512954480 cites W2005030689 @default.
• W2512954480 cites W2005877431 @default.
• W2512954480 cites W2007199559 @default.
• W2512954480 cites W2013407480 @default.
• W2512954480 cites W2016081624 @default.
• W2512954480 cites W2017562968 @default.
• W2512954480 cites W2023481842 @default.
• W2512954480 cites W2027212425 @default.
• W2512954480 cites W2033573257 @default.
• W2512954480 cites W2040257851 @default.
• W2512954480 cites W2043252348 @default.
• W2512954480 cites W2047382917 @default.
• W2512954480 cites W2058963315 @default.
• W2512954480 cites W2063807050 @default.
• W2512954480 cites W2064810566 @default.
• W2512954480 cites W2065505208 @default.
• W2512954480 cites W2076797886 @default.
• W2512954480 cites W2078234036 @default.
• W2512954480 cites W2118150538 @default.
• W2512954480 cites W2118441422 @default.
• W2512954480 cites W2130104282 @default.
• W2512954480 cites W2141024484 @default.
• W2512954480 cites W2149609127 @default.
• W2512954480 cites W2150086028 @default.
• W2512954480 cites W2152712144 @default.
• W2512954480 cites W2163467920 @default.
• W2512954480 cites W2171535052 @default.
• W2512954480 cites W2320577799 @default.
• W2512954480 doi "https://doi.org/10.4238/gmr.15038206" @default.
• W2512954480 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27706614" @default.
• W2512954480 hasPublicationYear "2016" @default.
• W2512954480 type Work @default.
• W2512954480 sameAs 2512954480 @default.
• W2512954480 citedByCount "2" @default.
• W2512954480 countsByYear W25129544802017 @default.
• W2512954480 countsByYear W25129544802020 @default.
• W2512954480 crossrefType "journal-article" @default.
• W2512954480 hasAuthorship W2512954480A5026111824 @default.
• W2512954480 hasAuthorship W2512954480A5027882467 @default.
• W2512954480 hasAuthorship W2512954480A5060028133 @default.
• W2512954480 hasAuthorship W2512954480A5066323748 @default.
• W2512954480 hasBestOaLocation W25129544801 @default.
• W2512954480 hasConcept C104317684 @default.
• W2512954480 hasConcept C119056186 @default.
• W2512954480 hasConcept C121608353 @default.
• W2512954480 hasConcept C126322002 @default.
• W2512954480 hasConcept C142724271 @default.
• W2512954480 hasConcept C143998085 @default.
• W2512954480 hasConcept C150194340 @default.
• W2512954480 hasConcept C190727270 @default.
• W2512954480 hasConcept C2776530083 @default.
• W2512954480 hasConcept C2776833033 @default.
• W2512954480 hasConcept C2778220009 @default.
• W2512954480 hasConcept C2778580637 @default.
• W2512954480 hasConcept C33288867 @default.
• W2512954480 hasConcept C502942594 @default.
• W2512954480 hasConcept C54355233 @default.
• W2512954480 hasConcept C71924100 @default.
• W2512954480 hasConcept C86803240 @default.
• W2512954480 hasConceptScore W2512954480C104317684 @default.
• W2512954480 hasConceptScore W2512954480C119056186 @default.
• W2512954480 hasConceptScore W2512954480C121608353 @default.
• W2512954480 hasConceptScore W2512954480C126322002 @default.
• W2512954480 hasConceptScore W2512954480C142724271 @default.
• W2512954480 hasConceptScore W2512954480C143998085 @default.
• W2512954480 hasConceptScore W2512954480C150194340 @default.
• W2512954480 hasConceptScore W2512954480C190727270 @default.
• W2512954480 hasConceptScore W2512954480C2776530083 @default.
• W2512954480 hasConceptScore W2512954480C2776833033 @default.
• W2512954480 hasConceptScore W2512954480C2778220009 @default.
• W2512954480 hasConceptScore W2512954480C2778580637 @default.
• W2512954480 hasConceptScore W2512954480C33288867 @default.
• W2512954480 hasConceptScore W2512954480C502942594 @default.
• W2512954480 hasConceptScore W2512954480C54355233 @default.
• W2512954480 hasConceptScore W2512954480C71924100 @default.
• W2512954480 hasConceptScore W2512954480C86803240 @default.
• W2512954480 hasIssue "3" @default.
• W2512954480 hasLocation W25129544801 @default.
• W2512954480 hasLocation W25129544802 @default.
• W2512954480 hasOpenAccess W2512954480 @default.
• W2512954480 hasPrimaryLocation W25129544801 @default.

• next