FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2513217162> ?p ?o ?g. }

• W2513217162 endingPage "233" @default.
• W2513217162 startingPage "230" @default.
• W2513217162 abstract "To investigate if reduction in procalcitonin (PCT) provides useful information about 28-day mortality in children with severe sepsis or septic shock. Design: Prospective observational study. Setting: Mixed adult-pediatric intensive care unit in a teaching hospital. Subjects: Children up to 18 years of age admitted with severe sepsis or septic shock between March 2011 and June 2013. Procalcitonin measured using electrochemiluminescence immunoassay on the day of admission with sepsis (D0) and 72-96 hours later (D4). Reduction in PCT from D0 to D4 correlated with the primary outcome, that is, 28-day mortality. Twenty-five children of median age of 14 years (range, 6-18 years) were included, but 5 died before D4 after admission. Six of the remaining 20 children died between D4 and D28, and 14 survived to D28. At admission, the median of the Pediatric Risk of Mortality III score was 10 (interquartile range [IQR], 5-16) and that of the Sequential Organ Failure Assessment score was 11 (IQR, 7-15). The median PCT level was 9.7 ng/mL on D0 (n = 25) and 3.3 ng/mL on D4 (n = 20). On D0, the median PCT level was 25.0 ng/mL in the 14 survivors and 8.4 ng/mL in the 11 nonsurvivors (P = .075). On D4, the median PCT level was 3.1 ng/mL in the 14 survivors and 4.5 ng/mL in the 6 nonsurvivors who lived to D4 (P = .71); the reduction in PCT (D0 minus D4) was 17.3 ng/mL (IQR, 3.5-38.0 ng/mL) in the survivors and −1.1 ng/mL (IQR, −24.9 to 8.6 ng/mL) in the 6 nonsurvivors (P = .017). Percent reduction in PCT (100 * [D0 − D4]/D0) was 75.5% (IQR, 54.8%-80.7%) in the survivors and −200.3% (IQR, −937.8% to 42.4%) in the 6 nonsurvivors (P = .006). This small pilot study suggests that further studies are indicated to determine whether children with severe sepsis or septic shock are less likely to die if they have a reduction in PCT more than 50% in the first 4 days in intensive care." @default.
• W2513217162 created "2016-09-16" @default.
• W2513217162 creator A5036519116 @default.
• W2513217162 creator A5051338275 @default.
• W2513217162 creator A5054123086 @default.
• W2513217162 creator A5058433874 @default.
• W2513217162 creator A5071874396 @default.
• W2513217162 date "2016-12-01" @default.
• W2513217162 modified "2023-09-27" @default.
• W2513217162 title "Reduction in procalcitonin level and outcome in critically ill children with severe sepsis/septic shock—A pilot study" @default.
• W2513217162 cites W1512952264 @default.
• W2513217162 cites W1974347586 @default.
• W2513217162 cites W1974564575 @default.
• W2513217162 cites W1974898015 @default.
• W2513217162 cites W1978963455 @default.
• W2513217162 cites W1986989818 @default.
• W2513217162 cites W2030200089 @default.
• W2513217162 cites W2038330119 @default.
• W2513217162 cites W2040674570 @default.
• W2513217162 cites W2053946384 @default.
• W2513217162 cites W2074372506 @default.
• W2513217162 cites W2076590961 @default.
• W2513217162 cites W2108282070 @default.
• W2513217162 cites W2114071909 @default.
• W2513217162 cites W2133885267 @default.
• W2513217162 cites W2152688162 @default.
• W2513217162 cites W2328326701 @default.
• W2513217162 doi "https://doi.org/10.1016/j.jcrc.2016.07.022" @default.
• W2513217162 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27566963" @default.
• W2513217162 hasPublicationYear "2016" @default.
• W2513217162 type Work @default.
• W2513217162 sameAs 2513217162 @default.
• W2513217162 citedByCount "14" @default.
• W2513217162 countsByYear W25132171622017 @default.
• W2513217162 countsByYear W25132171622018 @default.
• W2513217162 countsByYear W25132171622020 @default.
• W2513217162 countsByYear W25132171622023 @default.
• W2513217162 crossrefType "journal-article" @default.
• W2513217162 hasAuthorship W2513217162A5036519116 @default.
• W2513217162 hasAuthorship W2513217162A5051338275 @default.
• W2513217162 hasAuthorship W2513217162A5054123086 @default.
• W2513217162 hasAuthorship W2513217162A5058433874 @default.
• W2513217162 hasAuthorship W2513217162A5071874396 @default.
• W2513217162 hasConcept C10936531 @default.
• W2513217162 hasConcept C119060515 @default.
• W2513217162 hasConcept C126322002 @default.
• W2513217162 hasConcept C187212893 @default.
• W2513217162 hasConcept C188816634 @default.
• W2513217162 hasConcept C2776376669 @default.
• W2513217162 hasConcept C2777628635 @default.
• W2513217162 hasConcept C2778384902 @default.
• W2513217162 hasConcept C2778939556 @default.
• W2513217162 hasConcept C2781300812 @default.
• W2513217162 hasConcept C71924100 @default.
• W2513217162 hasConceptScore W2513217162C10936531 @default.
• W2513217162 hasConceptScore W2513217162C119060515 @default.
• W2513217162 hasConceptScore W2513217162C126322002 @default.
• W2513217162 hasConceptScore W2513217162C187212893 @default.
• W2513217162 hasConceptScore W2513217162C188816634 @default.
• W2513217162 hasConceptScore W2513217162C2776376669 @default.
• W2513217162 hasConceptScore W2513217162C2777628635 @default.
• W2513217162 hasConceptScore W2513217162C2778384902 @default.
• W2513217162 hasConceptScore W2513217162C2778939556 @default.
• W2513217162 hasConceptScore W2513217162C2781300812 @default.
• W2513217162 hasConceptScore W2513217162C71924100 @default.
• W2513217162 hasLocation W25132171621 @default.
• W2513217162 hasLocation W25132171622 @default.
• W2513217162 hasOpenAccess W2513217162 @default.
• W2513217162 hasPrimaryLocation W25132171621 @default.
• W2513217162 hasRelatedWork W2075482478 @default.
• W2513217162 hasRelatedWork W2083469568 @default.
• W2513217162 hasRelatedWork W2132787057 @default.
• W2513217162 hasRelatedWork W2513217162 @default.
• W2513217162 hasRelatedWork W2615425058 @default.
• W2513217162 hasRelatedWork W2732552819 @default.
• W2513217162 hasRelatedWork W3126744427 @default.
• W2513217162 hasRelatedWork W4245480233 @default.
• W2513217162 hasRelatedWork W4321360291 @default.
• W2513217162 hasRelatedWork W2290629160 @default.
• W2513217162 hasVolume "36" @default.
• W2513217162 isParatext "false" @default.
• W2513217162 isRetracted "false" @default.
• W2513217162 magId "2513217162" @default.
• W2513217162 workType "article" @default.