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- W2513304617 abstract "The dimeric napthoquione 5,8,4′-trihydroxy-1′-methoxy-6, 6′-dimethyl-7,3′-binaphtyl-1,4,5′,8′-tetraone (1) was isolated from the chloroform fraction of Diospyros lotus extract. Compound 1 was screened for its inhibitory effects against four enzymes: urease, phosphodiesterase-I, carbonic anhydrase-II and α-chymotrypsin, and showed selective activity against urease enzyme with an IC50 value of 254.1 ± 3.82 μM as compared to the standard thiourea (IC50 = 21 ± 0.11 μM). Furthermore, in silico docking study was carried out to explain the molecular mechanism of compound 1 against the target receptor." @default.
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- W2513304617 date "2016-09-01" @default.
- W2513304617 modified "2023-09-27" @default.
- W2513304617 title "Urease inhibition potential of Di-naphthodiospyrol from<i>Diospyros lotus</i>roots" @default.
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- W2513304617 doi "https://doi.org/10.1080/14786419.2016.1226832" @default.
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