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- W2513316222 abstract "Hemophagocytic lymphohistiocytosis (HLH) is a rare immune hyperactivation syndrome which may be primary (genetic) or secondary to various immune-related conditions including infection, immunodeficiency, and malignancies. Rapid diagnosis and treatment are essential because it can be associated with significant morbidity and mortality. Epstein-Barr virus (EBV) is a known infectious cause of acquired HLH, but EBV-associated HLH involving the central nervous system is rare and not well characterized neuropathologically. We report a case of fatal EBV-associated HLH with severe involvement of the central nervous system showing florid hemophagocytosis in the choroid plexus, with extensive neuron loss and gliosis in the cerebrum, cerebellum, and brainstem." @default.
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- W2513316222 date "2017-01-01" @default.
- W2513316222 modified "2023-10-16" @default.
- W2513316222 title "Hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus in the central nervous system" @default.
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- W2513316222 doi "https://doi.org/10.1016/j.humpath.2016.07.033" @default.
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