Matches in SemOpenAlex for { <https://semopenalex.org/work/W2513377914> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2513377914 endingPage "9" @default.
- W2513377914 startingPage "1" @default.
- W2513377914 abstract "Many tumor markers in relation to renal cell carcinoma (RCC) have been evaluated for detecting and monitoring diseases outcomes. However, none of these biomarkers reported to date has shown sufficient sensitivity and specificity for as a detector and prognosticator of the whole spectrum of RCC in routine clinical practice. The limited value of the established prognostic markers requires analysis of new molecular parameters of interest in predicting the prognosis of RCC patients; in particular, the high-risk patient groups at risk of recurrence and progression. Abnormal methylation of CpG islands can efficiently repress transcription of the associated gene in a manner akin to mutations and deletions. Recent progress in the understanding of epigenetic modification and gene silencing has provided new opportunities for the detection, treatment, and prevention of cancer. Methylation is an important molecular mechanism in RCC and could be used as a diagnostic and prognostic marker. Aberrant patterns of epigenetic modification would be, in near future, crucial parameters in cancer diagnosis, prognosis and a good target for developing novel therapies while maintaining the quality of life. This review discusses the epigenetic issues involved in the detection and prediction of prognosis in RCC." @default.
- W2513377914 created "2016-09-16" @default.
- W2513377914 creator A5051087755 @default.
- W2513377914 creator A5079186771 @default.
- W2513377914 date "2016-04-30" @default.
- W2513377914 modified "2023-09-23" @default.
- W2513377914 title "Methylation Markers in Renal Cell Carcinoma" @default.
- W2513377914 hasPublicationYear "2016" @default.
- W2513377914 type Work @default.
- W2513377914 sameAs 2513377914 @default.
- W2513377914 citedByCount "0" @default.
- W2513377914 crossrefType "journal-article" @default.
- W2513377914 hasAuthorship W2513377914A5051087755 @default.
- W2513377914 hasAuthorship W2513377914A5079186771 @default.
- W2513377914 hasConcept C104317684 @default.
- W2513377914 hasConcept C119056186 @default.
- W2513377914 hasConcept C121608353 @default.
- W2513377914 hasConcept C126322002 @default.
- W2513377914 hasConcept C140173407 @default.
- W2513377914 hasConcept C143998085 @default.
- W2513377914 hasConcept C150194340 @default.
- W2513377914 hasConcept C190727270 @default.
- W2513377914 hasConcept C2777472916 @default.
- W2513377914 hasConcept C2781068499 @default.
- W2513377914 hasConcept C33288867 @default.
- W2513377914 hasConcept C41091548 @default.
- W2513377914 hasConcept C502942594 @default.
- W2513377914 hasConcept C54355233 @default.
- W2513377914 hasConcept C60644358 @default.
- W2513377914 hasConcept C71924100 @default.
- W2513377914 hasConcept C86803240 @default.
- W2513377914 hasConceptScore W2513377914C104317684 @default.
- W2513377914 hasConceptScore W2513377914C119056186 @default.
- W2513377914 hasConceptScore W2513377914C121608353 @default.
- W2513377914 hasConceptScore W2513377914C126322002 @default.
- W2513377914 hasConceptScore W2513377914C140173407 @default.
- W2513377914 hasConceptScore W2513377914C143998085 @default.
- W2513377914 hasConceptScore W2513377914C150194340 @default.
- W2513377914 hasConceptScore W2513377914C190727270 @default.
- W2513377914 hasConceptScore W2513377914C2777472916 @default.
- W2513377914 hasConceptScore W2513377914C2781068499 @default.
- W2513377914 hasConceptScore W2513377914C33288867 @default.
- W2513377914 hasConceptScore W2513377914C41091548 @default.
- W2513377914 hasConceptScore W2513377914C502942594 @default.
- W2513377914 hasConceptScore W2513377914C54355233 @default.
- W2513377914 hasConceptScore W2513377914C60644358 @default.
- W2513377914 hasConceptScore W2513377914C71924100 @default.
- W2513377914 hasConceptScore W2513377914C86803240 @default.
- W2513377914 hasIssue "1" @default.
- W2513377914 hasLocation W25133779141 @default.
- W2513377914 hasOpenAccess W2513377914 @default.
- W2513377914 hasPrimaryLocation W25133779141 @default.
- W2513377914 hasRelatedWork W1615242633 @default.
- W2513377914 hasRelatedWork W1968907488 @default.
- W2513377914 hasRelatedWork W2032563963 @default.
- W2513377914 hasRelatedWork W2049540588 @default.
- W2513377914 hasRelatedWork W2053355772 @default.
- W2513377914 hasRelatedWork W2061663237 @default.
- W2513377914 hasRelatedWork W2098119888 @default.
- W2513377914 hasRelatedWork W2115704495 @default.
- W2513377914 hasRelatedWork W2128830878 @default.
- W2513377914 hasRelatedWork W2218471628 @default.
- W2513377914 hasRelatedWork W2252598301 @default.
- W2513377914 hasRelatedWork W2514896360 @default.
- W2513377914 hasRelatedWork W2560921010 @default.
- W2513377914 hasRelatedWork W2599493700 @default.
- W2513377914 hasRelatedWork W2792149160 @default.
- W2513377914 hasRelatedWork W2794713784 @default.
- W2513377914 hasRelatedWork W2993007839 @default.
- W2513377914 hasRelatedWork W3026913079 @default.
- W2513377914 hasRelatedWork W3045821955 @default.
- W2513377914 hasRelatedWork W3123278050 @default.
- W2513377914 hasVolume "14" @default.
- W2513377914 isParatext "false" @default.
- W2513377914 isRetracted "false" @default.
- W2513377914 magId "2513377914" @default.
- W2513377914 workType "article" @default.