Matches in SemOpenAlex for { <https://semopenalex.org/work/W2513617509> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2513617509 abstract "Perfluoro-n-octane is a high-density liquid perfluorocarbon used as a long-term vitreous replacement in vitreoretinal surgery. In this study, we assessed the toxicity of perfluoro-n-octane (PFOC) on Vero cells using an indirect toxicity test, scanning electron microscopy and immunocytochemistry. For indirect toxicity test, Vero cells were cultured for 12 h with PFOC extracts in 96-well plates and the plates were, then, read at 540 nm. For direct toxicity, Vero cells were incubated with 0.1 ml of perfluoro-n-octane alone. Glass coverslips were used as inert control for weight, to produce mechanical compression similar in weight and area to that caused by perfluoron-octane. Cells cultured without PFOC were used as a negative control. Silicone bands with a weight and area similar to those of perfluoro-n-octane served as a positive control for toxicity. The indirect toxicity test showed that perfluoro-n-octane did not release soluble toxic substances that affected cell growth. In the direct toxicity test, the cells in the control group had homogenously distributed actin filaments, although scanning electron microscopy revealed some vesicles on the cell surface. In the controls for weight, cytoplasmic retraction and the formation of thin cellular prolongations were seen. Cells incubated with perfluoro-n-octane showed greater changes compared to those seen in cells under a similar control weight. Silicone-treated cells had an irregular or fragmented morphology. These results show that, in addition to its compressive action on cultured cells, perfluoron-octane may also exert a toxic effect." @default.
- W2513617509 created "2016-09-16" @default.
- W2513617509 creator A5000001424 @default.
- W2513617509 creator A5010204990 @default.
- W2513617509 creator A5014648015 @default.
- W2513617509 creator A5073703163 @default.
- W2513617509 creator A5075904503 @default.
- W2513617509 creator A5076361831 @default.
- W2513617509 date "2002-01-01" @default.
- W2513617509 modified "2023-09-27" @default.
- W2513617509 title "THE CYTOTOXICITY IN VERO CELLS OF A PERFLUOROCARBON USED IN VITREORETINAL SURGERY" @default.
- W2513617509 cites W1987407027 @default.
- W2513617509 cites W1988792028 @default.
- W2513617509 cites W1993850072 @default.
- W2513617509 cites W1995803603 @default.
- W2513617509 cites W2004375854 @default.
- W2513617509 cites W2004564233 @default.
- W2513617509 cites W2005278867 @default.
- W2513617509 cites W2018636527 @default.
- W2513617509 cites W2030599839 @default.
- W2513617509 cites W2038856705 @default.
- W2513617509 cites W2040838620 @default.
- W2513617509 cites W2045415857 @default.
- W2513617509 cites W2054962186 @default.
- W2513617509 cites W2058824854 @default.
- W2513617509 cites W2076907450 @default.
- W2513617509 cites W2417098008 @default.
- W2513617509 cites W2427399309 @default.
- W2513617509 hasPublicationYear "2002" @default.
- W2513617509 type Work @default.
- W2513617509 sameAs 2513617509 @default.
- W2513617509 citedByCount "2" @default.
- W2513617509 crossrefType "journal-article" @default.
- W2513617509 hasAuthorship W2513617509A5000001424 @default.
- W2513617509 hasAuthorship W2513617509A5010204990 @default.
- W2513617509 hasAuthorship W2513617509A5014648015 @default.
- W2513617509 hasAuthorship W2513617509A5073703163 @default.
- W2513617509 hasAuthorship W2513617509A5075904503 @default.
- W2513617509 hasAuthorship W2513617509A5076361831 @default.
- W2513617509 hasConcept C109316439 @default.
- W2513617509 hasConcept C12554922 @default.
- W2513617509 hasConcept C13965031 @default.
- W2513617509 hasConcept C178790620 @default.
- W2513617509 hasConcept C185592680 @default.
- W2513617509 hasConcept C202751555 @default.
- W2513617509 hasConcept C2776624427 @default.
- W2513617509 hasConcept C29730261 @default.
- W2513617509 hasConcept C55493867 @default.
- W2513617509 hasConcept C86803240 @default.
- W2513617509 hasConcept C89138240 @default.
- W2513617509 hasConceptScore W2513617509C109316439 @default.
- W2513617509 hasConceptScore W2513617509C12554922 @default.
- W2513617509 hasConceptScore W2513617509C13965031 @default.
- W2513617509 hasConceptScore W2513617509C178790620 @default.
- W2513617509 hasConceptScore W2513617509C185592680 @default.
- W2513617509 hasConceptScore W2513617509C202751555 @default.
- W2513617509 hasConceptScore W2513617509C2776624427 @default.
- W2513617509 hasConceptScore W2513617509C29730261 @default.
- W2513617509 hasConceptScore W2513617509C55493867 @default.
- W2513617509 hasConceptScore W2513617509C86803240 @default.
- W2513617509 hasConceptScore W2513617509C89138240 @default.
- W2513617509 hasLocation W25136175091 @default.
- W2513617509 hasOpenAccess W2513617509 @default.
- W2513617509 hasPrimaryLocation W25136175091 @default.
- W2513617509 hasRelatedWork W1984563102 @default.
- W2513617509 hasRelatedWork W2011515130 @default.
- W2513617509 hasRelatedWork W2018335539 @default.
- W2513617509 hasRelatedWork W2033947583 @default.
- W2513617509 hasRelatedWork W2035500755 @default.
- W2513617509 hasRelatedWork W2043418335 @default.
- W2513617509 hasRelatedWork W2072760187 @default.
- W2513617509 hasRelatedWork W2141883105 @default.
- W2513617509 hasRelatedWork W2349886346 @default.
- W2513617509 hasRelatedWork W2353400168 @default.
- W2513617509 hasRelatedWork W2370310516 @default.
- W2513617509 hasRelatedWork W2410572202 @default.
- W2513617509 hasRelatedWork W2789723135 @default.
- W2513617509 hasRelatedWork W3029249084 @default.
- W2513617509 hasRelatedWork W85984155 @default.
- W2513617509 hasRelatedWork W863097918 @default.
- W2513617509 hasRelatedWork W90355088 @default.
- W2513617509 hasRelatedWork W2182615202 @default.
- W2513617509 hasRelatedWork W2188142844 @default.
- W2513617509 hasRelatedWork W239580083 @default.
- W2513617509 isParatext "false" @default.
- W2513617509 isRetracted "false" @default.
- W2513617509 magId "2513617509" @default.
- W2513617509 workType "article" @default.