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• W2513631567 abstract "Background: The EpiNet database has been established to facilitate clinical research in epilepsy. It has now been adapted to collect detailed information on patients with status epilepticus (SE). Objectives: To conduct an incidence study of SE in Auckland; to develop EpiNet for multicentre clinical trials in SE. Methods: New forms have been created in EpiNet to record detailed information regarding SE. The forms precisely record time of onset and duration of SE. The time and route of administration of various treatments - conventional anti-epileptic drugs and other treatments (anaesthetic agents, steroids, other immunosuppressive drug treatment, intravenous immunoglobulin, plasma-exchange, ventilation, cooling, diet) - is recorded in a similar manner. A prospective, incidence study of SE is underway in the Greater Auckland area (population 1.5 million). Information is being systematically collected over 12 months from early April 2015 on all patients over 4 weeks of age who have a seizure of more than 10 minutes duration (definition of SE for this study). Patients will be followed for 2 years. We have obtained patient and Institutional Review Board (IRB) approval, as necessary. Results: Descriptive statistics will be provided on demographic and clinical variables, and the incidence of SE in Auckland (per 100,000 person years with 95%CI) will be determined . The adjusted hazard ratio will be calculated for possible prognostic factors (age, sex, ethnic group, seizure type, aetiology, and duration). Conclusions: The incidence, causes, responses to treatment, and outcomes of SE in Greater Auckland will be determined. The EpiNet database is now able to conduct multi-centre randomised controlled trials in SE." @default.
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• W2513631567 date "2015-10-01" @default.
• W2513631567 modified "2023-09-27" @default.
• W2513631567 title "Use of epinet database for observational study of status epilepticus in Auckland, New Zealand" @default.
• W2513631567 doi "https://doi.org/10.1016/j.jns.2015.08.490" @default.
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