Matches in SemOpenAlex for { <https://semopenalex.org/work/W2513994325> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2513994325 abstract "Categorization of patients with COPD as reversible or nonreversible to a bronchodilator may change over time. This post hoc analysis aimed to determine if an individual's reversibility, when treated as a continuous variable, could predict his/her future response to two short-acting bronchodilators: albuterol and ipratropium. The analysis was completed using data from a 4-week, randomized, open-label, two-period crossover study (NCT01691482; GSK study DB2114956). Patients received albuterol (doses: UK =4×100 μg/puff; US =4×90 μg/puff) followed 1 hour later by ipratropium (4×20 μg/puff) or vice versa during treatment Period 1. The order of treatments was reversed during Period 2. Predefined efficacy end points included pre- and post-bronchodilator forced expiratory volume in 1 second. The correlation coefficient between bronchodilator response on Days 1 and 10 was investigated, as well as the correlation between treatment response on Day 1 and the mean treatment response on Days 5-10, for each individual patient. Bronchodilator response to albuterol on Day 1 was strongly correlated with that on Day 10 (r=0.64; n=53). The correlation coefficient of bronchodilator treatment response on Day 1 and Days 5-10 was 0.78 (P<0.001; n=53) and 0.76 (P<0.001; n=54) for albuterol and ipratropium, respectively. A single measurement of the initial bronchodilator response to albuterol or ipratropium was, therefore, highly correlated with the subsequent mean bronchodilator response over 5-10 days, demonstrating its potential usefulness for future treatment decisions." @default.
- W2513994325 created "2016-09-16" @default.
- W2513994325 creator A5004214379 @default.
- W2513994325 creator A5007172600 @default.
- W2513994325 creator A5068917661 @default.
- W2513994325 creator A5073480128 @default.
- W2513994325 date "2016-08-01" @default.
- W2513994325 modified "2023-09-27" @default.
- W2513994325 title "Bronchodilator reversibility in patients with COPD revisited: short-term reproducibility" @default.
- W2513994325 cites W2017710496 @default.
- W2513994325 cites W2022916022 @default.
- W2513994325 cites W2109006492 @default.
- W2513994325 cites W2113442593 @default.
- W2513994325 cites W2117237679 @default.
- W2513994325 cites W2127951128 @default.
- W2513994325 cites W2128643475 @default.
- W2513994325 cites W2130049277 @default.
- W2513994325 cites W2142983489 @default.
- W2513994325 cites W2143454168 @default.
- W2513994325 cites W2144711807 @default.
- W2513994325 cites W2149088199 @default.
- W2513994325 cites W2164158986 @default.
- W2513994325 cites W2166432084 @default.
- W2513994325 cites W4211263216 @default.
- W2513994325 doi "https://doi.org/10.2147/copd.s108723" @default.
- W2513994325 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5010081" @default.
- W2513994325 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27621609" @default.
- W2513994325 hasPublicationYear "2016" @default.
- W2513994325 type Work @default.
- W2513994325 sameAs 2513994325 @default.
- W2513994325 citedByCount "6" @default.
- W2513994325 countsByYear W25139943252017 @default.
- W2513994325 countsByYear W25139943252018 @default.
- W2513994325 countsByYear W25139943252019 @default.
- W2513994325 countsByYear W25139943252020 @default.
- W2513994325 countsByYear W25139943252021 @default.
- W2513994325 crossrefType "journal-article" @default.
- W2513994325 hasAuthorship W2513994325A5004214379 @default.
- W2513994325 hasAuthorship W2513994325A5007172600 @default.
- W2513994325 hasAuthorship W2513994325A5068917661 @default.
- W2513994325 hasAuthorship W2513994325A5073480128 @default.
- W2513994325 hasBestOaLocation W25139943251 @default.
- W2513994325 hasConcept C126322002 @default.
- W2513994325 hasConcept C142724271 @default.
- W2513994325 hasConcept C204787440 @default.
- W2513994325 hasConcept C27081682 @default.
- W2513994325 hasConcept C2776042228 @default.
- W2513994325 hasConcept C2776780178 @default.
- W2513994325 hasConcept C2780532441 @default.
- W2513994325 hasConcept C2781018748 @default.
- W2513994325 hasConcept C2909577894 @default.
- W2513994325 hasConcept C42219234 @default.
- W2513994325 hasConcept C71924100 @default.
- W2513994325 hasConcept C87813604 @default.
- W2513994325 hasConceptScore W2513994325C126322002 @default.
- W2513994325 hasConceptScore W2513994325C142724271 @default.
- W2513994325 hasConceptScore W2513994325C204787440 @default.
- W2513994325 hasConceptScore W2513994325C27081682 @default.
- W2513994325 hasConceptScore W2513994325C2776042228 @default.
- W2513994325 hasConceptScore W2513994325C2776780178 @default.
- W2513994325 hasConceptScore W2513994325C2780532441 @default.
- W2513994325 hasConceptScore W2513994325C2781018748 @default.
- W2513994325 hasConceptScore W2513994325C2909577894 @default.
- W2513994325 hasConceptScore W2513994325C42219234 @default.
- W2513994325 hasConceptScore W2513994325C71924100 @default.
- W2513994325 hasConceptScore W2513994325C87813604 @default.
- W2513994325 hasLocation W25139943251 @default.
- W2513994325 hasLocation W25139943252 @default.
- W2513994325 hasLocation W25139943253 @default.
- W2513994325 hasOpenAccess W2513994325 @default.
- W2513994325 hasPrimaryLocation W25139943251 @default.
- W2513994325 hasRelatedWork W1987277876 @default.
- W2513994325 hasRelatedWork W1988797668 @default.
- W2513994325 hasRelatedWork W2052143664 @default.
- W2513994325 hasRelatedWork W2104616045 @default.
- W2513994325 hasRelatedWork W2130712849 @default.
- W2513994325 hasRelatedWork W2132457952 @default.
- W2513994325 hasRelatedWork W2185288238 @default.
- W2513994325 hasRelatedWork W2395499023 @default.
- W2513994325 hasRelatedWork W2417675867 @default.
- W2513994325 hasRelatedWork W2416259321 @default.
- W2513994325 isParatext "false" @default.
- W2513994325 isRetracted "false" @default.
- W2513994325 magId "2513994325" @default.
- W2513994325 workType "article" @default.