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• W2514036218 abstract "La prevención del parto prematuro es uno de los desafíos de la obstetricia en el siglo XXI. Los prematuros tienen riesgo de morbimortalidad perinatal, sobre todos los nacidos antes de las 30 semanas, tienen mayor riesgo de lesiones neurológicas generalmente secundarias a isquemia o infección intrauterina ascendente. Existen estrategias para prevenir el daño neurológico fetal en el trabajo de parto prematuro. La administración de sulfato de magnesio endovenoso reduce en forma significativa la probabilidad de desarrollar parálisis cerebral y disfunciones motoras. También se ha mostrado la utilidad del pinzamiento tardío del cordón umbilical y la administración antenatal y postnatal de N-acetilcisteína. En estudios animales se ha observado un potencial efecto neuroprotector de stem cells mesenquimáticas, estradiol y progesterona, melatonina y creatina. The prevention of preterm birth represents one of the most significant challenges to the field of obstetrics in the 21st century. Preterm infants have risk of perinatal mortality and morbidity. Preterm infants born before the 30th week of pregnancy are especially at risk of perinatal brain damage which is usually a result of cerebral ischemia or an ascending intrauterine infection. The prophylaxis against fetal neuronal injury during threatened preterm labor. It has been shown that administering magnesium intravenously leads to a significant reduction in the likelihood of the infant developing cerebral palsy and motor skill dysfunction. It has also been demonstrated utility that delayed clamping of the umbilical cord after birth and administration antenatal and postnatal N-acetylcysteine. In addition, mesenchymal stem cells, estradiol and progesterone, melatonin and creatine seem to have significant neuroprotective potential in animal experiments." @default.
• W2514036218 created "2016-09-16" @default.
• W2514036218 creator A5061983452 @default.
• W2514036218 date "2016-07-01" @default.
• W2514036218 modified "2023-10-14" @default.
• W2514036218 title "PREVENCIÓN PRENATAL DE DAÑO NEUROLÓGICO EN PREMATURO EXTREMO" @default.
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• W2514036218 doi "https://doi.org/10.1016/j.rmclc.2016.07.003" @default.
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