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• W2514055248 abstract "Many disease-modifying therapies are currently available for adults with relapsing-remitting multiple sclerosis (MS) but none of them has been tested in pediatric MS in randomized placebo-controlled trials. At present, as suggested by observational studies and experts9 guidelines, interferon-β and glatiramer acetate continue to be the standard first-line treatments for pediatric MS. Observational studies and some controlled unblinded trials have shown a positive effect of these meditations in reducing relapse rate and delaying disease progression, with an acceptable safety profile. The goal of this article is to provide an overview of current knowledge with regard to safety, tolerability, and efficacy of first-line treatment options for MS in the pediatric age group, with the aim of providing guidance for planning first-line treatment of MS in children and adolescents." @default.
• W2514055248 created "2016-09-16" @default.
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• W2514055248 date "2016-08-29" @default.
• W2514055248 modified "2023-09-28" @default.
• W2514055248 title "Pediatric multiple sclerosis" @default.
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• W2514055248 doi "https://doi.org/10.1212/wnl.0000000000002823" @default.
• W2514055248 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27572869" @default.
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