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- W2514110068 abstract "The lamprey central pattern generator (CPG) for locomotion consists of a collection of neurons in the spinal cord that is responsible for producing the rhythmic neural activity used for swimming. Mechanoreceptors in the margin of the spinal cord, called edge cells, detect the bending of the body and provide sensory feedback for the CPG. Thus, edge cells are essential for the CPG’s ability to respond to perturbations. To investigate the CPG’s response to perturbations during swimming, we compute entrainment ranges for stochastic bending signals where Gaussian band-limited white noise is added on top of a sinusoidal signal. Experimentally, the lamprey spinal cord was bent back-and-forth to entrain the CPG’s rhythm, and then Gaussian band-limited white noise was added to the sensory stimulus. Correspondingly, we also developed mathematical models of the CPG circuit. Using the same stimuli in the models as was used in the experiment, we examine which properties of the CPG circuit are related to the observed experimental results." @default.
- W2514110068 created "2016-09-16" @default.
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- W2514110068 date "2016-01-01" @default.
- W2514110068 modified "2023-10-09" @default.
- W2514110068 title "Understanding Locomotor Rhythm in the Lamprey Central Pattern Generator" @default.
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- W2514110068 doi "https://doi.org/10.1007/978-3-319-34139-2_6" @default.
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