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• W2514290116 abstract "We read the article “Comparison of Intraocular Pressure Post Penetrating Keratoplasty vs Descemet’s Stripping Endothelial Keratoplasty” by Sharma et al. with great interest.1Sharma R.A. Bursztyn L.L. Golesic E. et al.Comparison of intraocular pressure post penetrating keratoplasty vs Descemet’s stripping endothelial keratoplasty.Can J Ophthalmol. 2016; 51: 19-24Abstract Full Text Full Text PDF PubMed Scopus (12) Google Scholar The authors aimed to compare the effect of Descemet’s stripping endothelial keratoplasty (DSEK) with penetrating keratoplasty (PKP) on intraocular pressure (IOP). We congratulate the authors and would like to report an error and make some contributions about the study. The authors reported that there was no significant difference in preoperative IOP between the 2 groups. In addition, postoperative IOP was significantly higher in the PKP group at 1 week and 4, 8, and 12 weeks but not at 24 weeks. However, we see that the authors did not take into account the time of day when they measured the IOP, although it has been reported that IOP shows important diurnal variation. IOP increases during the evening and night and peaks between 2:30 and 4:30 am. On the contrary, it progressively decreases in the early afternoon and afternoon, especially between 11:00 am and 5:00 pm. It has been reported that IOP fluctuations range from 2 to 6 mm Hg over a 24-hour period, whereas in eyes with glaucoma the fluctuations can be more than 10 mm Hg.2Sit A.J. Intraocular pressure variations: causes and clinical significance.Can J Ophthalmol. 2014; 49: 484-488Abstract Full Text Full Text PDF PubMed Scopus (36) Google Scholar, 3Agnifili L. Mastropasqua R. Frezzotti P. et al.Circadian intraocular pressure patterns in healthy subjects, primary open angle and normal tension glaucoma patients with a contact lens sensor.Acta Ophthalmol. 2015; 93: e14-21Crossref PubMed Scopus (88) Google Scholar Therefore, measuring the IOP of each patient or different patients at different hours might have affected the results of the present study. The authors also reported that all patients had used topical corticosteroid medication during the study, but they did not state whether all patients used the same or different corticosteroid drop. It has been reported that different corticosteroid drops have different abilities in elevating IOP; for instance, dexamethasone 0.1% is 2 times more powerful than prednisolone 1.0% and 3 times more powerful than fluorometholone 0.1% in elevating IOP.4Razeghinejad M.R. Katz L.J. Steroid-induced iatrogenic glaucoma.Ophthalmic Res. 2012; 47: 66-80Crossref PubMed Scopus (152) Google Scholar, 5Yamamoto Y. Komatsu T. Koura Y. Intraocular pressure elevation after intravitreal or posterior sub-Tenon triamcinolone acetonide injection.Can J Ophthalmol. 2008; 43: 42-47Abstract Full Text PDF PubMed Scopus (0) Google Scholar Therefore, if patients used different types of steroids, this might have affected the results. Additionally, they reported that a preoperative diagnosis of glaucoma was noted in 27 patients overall: 15 in the PKP group and 12 in the DSEK group. The etiology of glaucoma was primary open-angle glaucoma (n = 15), iridocorneal endothelial syndrome (n = 3), pseudoexfoliation (n = 2), and angle-closure glaucoma (n = 2), but information about glaucoma etiology of 5 patients is not given." @default.
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• W2514290116 date "2016-12-01" @default.
• W2514290116 modified "2023-09-25" @default.
• W2514290116 title "Circadian rhythm affects ıntraocular pressure level after penetrating keratoplasty and Descemet’s stripping" @default.
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• W2514290116 doi "https://doi.org/10.1016/j.jcjo.2016.05.012" @default.
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