FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2514340074> ?p ?o ?g. }

• W2514340074 endingPage "8" @default.
• W2514340074 startingPage "1" @default.
• W2514340074 abstract "Betulin 1 and its semisynthetic derivatives exhibit a cytotoxic activity toward various cancer cell lines. These compounds are a promising and potential anticancer candidates. A series of betulin derivatives was prepared and tested for the antiproliferative activity in vitro against T47D breast cancer, CCRF/CEM leukemia, HL-60 promyelocytic leukemia, SW707 colorectal, murine P388 leukemia, as well as BALB3T3 normal fibroblasts cell lines. Cisplatin and betulin 1 were used as a reference compounds. Some derivatives of betulin showed a higher cytotoxic activity than the parent compound 1. Two derivatives (5 and 17) were 24-fold potent than betulin 1 against the human promyelocytic leukemia cell line (HL-60), with an IC50 value of 0.3 µg/mL." @default.
• W2514340074 created "2016-09-16" @default.
• W2514340074 creator A5016096557 @default.
• W2514340074 creator A5022446752 @default.
• W2514340074 creator A5027844724 @default.
• W2514340074 creator A5036936324 @default.
• W2514340074 creator A5044749284 @default.
• W2514340074 creator A5091846316 @default.
• W2514340074 date "2016-09-01" @default.
• W2514340074 modified "2023-10-15" @default.
• W2514340074 title "New acetylenic derivatives of betulin and betulone, synthesis and cytotoxic activity" @default.
• W2514340074 cites W1229371060 @default.
• W2514340074 cites W1976307886 @default.
• W2514340074 cites W1981664093 @default.
• W2514340074 cites W1982550819 @default.
• W2514340074 cites W1986218330 @default.
• W2514340074 cites W1986802581 @default.
• W2514340074 cites W1992198584 @default.
• W2514340074 cites W2000371332 @default.
• W2514340074 cites W2016457621 @default.
• W2514340074 cites W2018729684 @default.
• W2514340074 cites W2027865966 @default.
• W2514340074 cites W2037468156 @default.
• W2514340074 cites W2039991473 @default.
• W2514340074 cites W2040626078 @default.
• W2514340074 cites W2047034083 @default.
• W2514340074 cites W2053693087 @default.
• W2514340074 cites W2060522502 @default.
• W2514340074 cites W2084383881 @default.
• W2514340074 cites W2090953188 @default.
• W2514340074 cites W2105613925 @default.
• W2514340074 cites W2109689528 @default.
• W2514340074 cites W2115728204 @default.
• W2514340074 cites W2332622803 @default.
• W2514340074 doi "https://doi.org/10.1007/s00044-016-1713-9" @default.
• W2514340074 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5219024" @default.
• W2514340074 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28111514" @default.
• W2514340074 hasPublicationYear "2016" @default.
• W2514340074 type Work @default.
• W2514340074 sameAs 2514340074 @default.
• W2514340074 citedByCount "25" @default.
• W2514340074 countsByYear W25143400742017 @default.
• W2514340074 countsByYear W25143400742018 @default.
• W2514340074 countsByYear W25143400742019 @default.
• W2514340074 countsByYear W25143400742020 @default.
• W2514340074 countsByYear W25143400742021 @default.
• W2514340074 countsByYear W25143400742022 @default.
• W2514340074 countsByYear W25143400742023 @default.
• W2514340074 crossrefType "journal-article" @default.
• W2514340074 hasAuthorship W2514340074A5016096557 @default.
• W2514340074 hasAuthorship W2514340074A5022446752 @default.
• W2514340074 hasAuthorship W2514340074A5027844724 @default.
• W2514340074 hasAuthorship W2514340074A5036936324 @default.
• W2514340074 hasAuthorship W2514340074A5044749284 @default.
• W2514340074 hasAuthorship W2514340074A5091846316 @default.
• W2514340074 hasBestOaLocation W25143400741 @default.
• W2514340074 hasConcept C104317684 @default.
• W2514340074 hasConcept C109316439 @default.
• W2514340074 hasConcept C126322002 @default.
• W2514340074 hasConcept C154317977 @default.
• W2514340074 hasConcept C185592680 @default.
• W2514340074 hasConcept C202751555 @default.
• W2514340074 hasConcept C203014093 @default.
• W2514340074 hasConcept C2776601000 @default.
• W2514340074 hasConcept C2776694085 @default.
• W2514340074 hasConcept C2778239845 @default.
• W2514340074 hasConcept C2778461978 @default.
• W2514340074 hasConcept C2778509883 @default.
• W2514340074 hasConcept C2781121885 @default.
• W2514340074 hasConcept C54355233 @default.
• W2514340074 hasConcept C55493867 @default.
• W2514340074 hasConcept C71924100 @default.
• W2514340074 hasConcept C81885089 @default.
• W2514340074 hasConcept C86803240 @default.
• W2514340074 hasConcept C98274493 @default.
• W2514340074 hasConceptScore W2514340074C104317684 @default.
• W2514340074 hasConceptScore W2514340074C109316439 @default.
• W2514340074 hasConceptScore W2514340074C126322002 @default.
• W2514340074 hasConceptScore W2514340074C154317977 @default.
• W2514340074 hasConceptScore W2514340074C185592680 @default.
• W2514340074 hasConceptScore W2514340074C202751555 @default.
• W2514340074 hasConceptScore W2514340074C203014093 @default.
• W2514340074 hasConceptScore W2514340074C2776601000 @default.
• W2514340074 hasConceptScore W2514340074C2776694085 @default.
• W2514340074 hasConceptScore W2514340074C2778239845 @default.
• W2514340074 hasConceptScore W2514340074C2778461978 @default.
• W2514340074 hasConceptScore W2514340074C2778509883 @default.
• W2514340074 hasConceptScore W2514340074C2781121885 @default.
• W2514340074 hasConceptScore W2514340074C54355233 @default.
• W2514340074 hasConceptScore W2514340074C55493867 @default.
• W2514340074 hasConceptScore W2514340074C71924100 @default.
• W2514340074 hasConceptScore W2514340074C81885089 @default.
• W2514340074 hasConceptScore W2514340074C86803240 @default.
• W2514340074 hasConceptScore W2514340074C98274493 @default.
• W2514340074 hasIssue "1" @default.
• W2514340074 hasLocation W25143400741 @default.
• W2514340074 hasLocation W25143400742 @default.
• W2514340074 hasLocation W25143400743 @default.

• next