Matches in SemOpenAlex for { <https://semopenalex.org/work/W2514444724> ?p ?o ?g. }
- W2514444724 endingPage "91" @default.
- W2514444724 startingPage "74" @default.
- W2514444724 abstract "Substance addiction may follow a chronic, relapsing course and critically undermine the physical and psychological well‐being of the affected individual and the social units of which the individual is a member. Despite the public health burden associated with substance addiction, treatment options remain suboptimal, with relapses often seen. The present review synthesizes growing insights from animal and human research to shed light upon developmental and neurobiological pathways that may increase susceptibility to addiction. We examine the dopamine system, the oxytocin system, and the glucocorticoid system, as they are particularly relevant to substance addiction. Our aim is to delineate how early adverse experience may induce long‐lasting alterations in each of these systems at molecular, neuroendocrine, and behavioral levels and ultimately lead to heightened vulnerability to substance addiction. We further discuss how substance addiction in adulthood may increase the risk of suboptimal caregiving for the next generation, perpetuating the intergenerational cycle of early adverse experiences and addiction." @default.
- W2514444724 created "2016-09-16" @default.
- W2514444724 creator A5009410558 @default.
- W2514444724 creator A5030470731 @default.
- W2514444724 creator A5032271246 @default.
- W2514444724 creator A5067499997 @default.
- W2514444724 creator A5080195733 @default.
- W2514444724 creator A5091596328 @default.
- W2514444724 date "2016-08-10" @default.
- W2514444724 modified "2023-09-29" @default.
- W2514444724 title "Early adverse experience and substance addiction: dopamine, oxytocin, and glucocorticoid pathways" @default.
- W2514444724 cites W1132316397 @default.
- W2514444724 cites W1502557671 @default.
- W2514444724 cites W1511351296 @default.
- W2514444724 cites W1511386490 @default.
- W2514444724 cites W1518574168 @default.
- W2514444724 cites W1520271859 @default.
- W2514444724 cites W1524639847 @default.
- W2514444724 cites W1546098811 @default.
- W2514444724 cites W1550381749 @default.
- W2514444724 cites W1556392272 @default.
- W2514444724 cites W1635412086 @default.
- W2514444724 cites W1848009667 @default.
- W2514444724 cites W1933889792 @default.
- W2514444724 cites W1964035308 @default.
- W2514444724 cites W1964173716 @default.
- W2514444724 cites W1964838523 @default.
- W2514444724 cites W1965811933 @default.
- W2514444724 cites W1966259448 @default.
- W2514444724 cites W1969854425 @default.
- W2514444724 cites W1970577797 @default.
- W2514444724 cites W1975799116 @default.
- W2514444724 cites W1976761215 @default.
- W2514444724 cites W1979293468 @default.
- W2514444724 cites W1979295154 @default.
- W2514444724 cites W1980704757 @default.
- W2514444724 cites W1981459575 @default.
- W2514444724 cites W1981793227 @default.
- W2514444724 cites W1982340672 @default.
- W2514444724 cites W1983339301 @default.
- W2514444724 cites W1984424676 @default.
- W2514444724 cites W1984427714 @default.
- W2514444724 cites W1985378500 @default.
- W2514444724 cites W1985852293 @default.
- W2514444724 cites W1987028639 @default.
- W2514444724 cites W1987261189 @default.
- W2514444724 cites W1987375729 @default.
- W2514444724 cites W1987515667 @default.
- W2514444724 cites W1989197363 @default.
- W2514444724 cites W1989416066 @default.
- W2514444724 cites W1989873034 @default.
- W2514444724 cites W1990902502 @default.
- W2514444724 cites W1991163868 @default.
- W2514444724 cites W1991317645 @default.
- W2514444724 cites W1991733912 @default.
- W2514444724 cites W1991882455 @default.
- W2514444724 cites W1992888278 @default.
- W2514444724 cites W1993339132 @default.
- W2514444724 cites W1993897510 @default.
- W2514444724 cites W1994014181 @default.
- W2514444724 cites W1996664667 @default.
- W2514444724 cites W1997170756 @default.
- W2514444724 cites W1998030203 @default.
- W2514444724 cites W1998033984 @default.
- W2514444724 cites W1999262788 @default.
- W2514444724 cites W2000275272 @default.
- W2514444724 cites W2001187532 @default.
- W2514444724 cites W2001574712 @default.
- W2514444724 cites W2001992324 @default.
- W2514444724 cites W2003308034 @default.
- W2514444724 cites W2004120576 @default.
- W2514444724 cites W2004787375 @default.
- W2514444724 cites W2004987149 @default.
- W2514444724 cites W2006098079 @default.
- W2514444724 cites W2006406555 @default.
- W2514444724 cites W2006773863 @default.
- W2514444724 cites W2007010563 @default.
- W2514444724 cites W2008675986 @default.
- W2514444724 cites W2011044338 @default.
- W2514444724 cites W2011526238 @default.
- W2514444724 cites W2011628863 @default.
- W2514444724 cites W2011987020 @default.
- W2514444724 cites W2013824495 @default.
- W2514444724 cites W2014485033 @default.
- W2514444724 cites W2015292608 @default.
- W2514444724 cites W2015354810 @default.
- W2514444724 cites W2017838119 @default.
- W2514444724 cites W2018303025 @default.
- W2514444724 cites W2020291009 @default.
- W2514444724 cites W2023636464 @default.
- W2514444724 cites W2025032083 @default.
- W2514444724 cites W2026907794 @default.
- W2514444724 cites W2028939120 @default.
- W2514444724 cites W2028971980 @default.
- W2514444724 cites W2033420771 @default.
- W2514444724 cites W2033746591 @default.
- W2514444724 cites W2033905698 @default.
- W2514444724 cites W2034413695 @default.