Matches in SemOpenAlex for { <https://semopenalex.org/work/W2514515907> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2514515907 abstract "The Phytochemical study of Methanol/dichloromethane extrac of the leaves of Dissotis perkinsia led to the isolation and identification seven compounds: Ursolic acid (1); Sitosterol-β-D-glucoside (2); Isoquercitrin (3);Quercetin-3-O-β-galactoside (4);Kaempferol-3-O-β-D-glucoside (5); Kaempferol-7-O-β-D-glucoside (6); Trans-Tiliroside(7). Their structures were elucidated on the basis of spectroscopic analysis and by comparison of their spectral data with those reported in the literature. The results of antimicrobial activity indicated that the MIC vary from >0.5 to 0.00078 mg/mL on yeasts and from >0.5 to 0.25 mg/mL on bacteria. Sitosterol-β-D-glucoside was the most active with the broad spectrum (MIC=0.125mg/mL on C. albicans, MIC=0.0625 mg/mL on C. kruseiand MIC=0.0078 mg/mL on C. parapsilosis). Kaempferol-7-O-β-D-glucoside was the most active on C. krusei (MIC=0.0039 mg/mL). The anti yeat activity of Sitosterol-β-D-glucoside and Kaempferol-7-O-β-D-glucoside were better thanfluconazole (0.032mg/mL) on C. parapsilosis (MIC 0.0078 mg/mL) andC. krusei (0.0039mg/mL) respectively. Sitosterol-β-D-glucoside and Trans-Tiliroside showed weak inhibitotry activity against S. enteric and S. aureus with MIC value of 0.5mg/mL. Respectively this inhibitory effect was lower activities observed with Chloremphenicol and Ampicillin (0.000488 mg/mL). The results of this study suggest that Dissotis perkinsiae represent an untapped source of compounds with potential antimicrobial activity that could be explored in the development of new therapeutic natural products.Keyword: Dissotis perkinsiae, Phytochemistry, Antimicrobial activity" @default.
- W2514515907 created "2016-09-16" @default.
- W2514515907 creator A5015616955 @default.
- W2514515907 creator A5018485900 @default.
- W2514515907 creator A5026719878 @default.
- W2514515907 creator A5055848699 @default.
- W2514515907 creator A5056778963 @default.
- W2514515907 creator A5069250338 @default.
- W2514515907 creator A5069848980 @default.
- W2514515907 creator A5071792272 @default.
- W2514515907 date "2016-01-01" @default.
- W2514515907 modified "2023-09-26" @default.
- W2514515907 title "Chemical Constituents of Dissotis perkinsiae (Melastomaceae) and Their Antimicrobial Activity" @default.
- W2514515907 cites W1983475809 @default.
- W2514515907 cites W1996713129 @default.
- W2514515907 cites W2051903523 @default.
- W2514515907 cites W2110837175 @default.
- W2514515907 cites W2134389003 @default.
- W2514515907 cites W2162331245 @default.
- W2514515907 doi "https://doi.org/10.7324/japs.2016.60815" @default.
- W2514515907 hasPublicationYear "2016" @default.
- W2514515907 type Work @default.
- W2514515907 sameAs 2514515907 @default.
- W2514515907 citedByCount "2" @default.
- W2514515907 countsByYear W25145159072018 @default.
- W2514515907 countsByYear W25145159072020 @default.
- W2514515907 crossrefType "journal-article" @default.
- W2514515907 hasAuthorship W2514515907A5015616955 @default.
- W2514515907 hasAuthorship W2514515907A5018485900 @default.
- W2514515907 hasAuthorship W2514515907A5026719878 @default.
- W2514515907 hasAuthorship W2514515907A5055848699 @default.
- W2514515907 hasAuthorship W2514515907A5056778963 @default.
- W2514515907 hasAuthorship W2514515907A5069250338 @default.
- W2514515907 hasAuthorship W2514515907A5069848980 @default.
- W2514515907 hasAuthorship W2514515907A5071792272 @default.
- W2514515907 hasBestOaLocation W25145159071 @default.
- W2514515907 hasConcept C142724271 @default.
- W2514515907 hasConcept C176947019 @default.
- W2514515907 hasConcept C178790620 @default.
- W2514515907 hasConcept C185592680 @default.
- W2514515907 hasConcept C195475562 @default.
- W2514515907 hasConcept C204787440 @default.
- W2514515907 hasConcept C2777810353 @default.
- W2514515907 hasConcept C2778004101 @default.
- W2514515907 hasConcept C2781263971 @default.
- W2514515907 hasConcept C2781347565 @default.
- W2514515907 hasConcept C43617362 @default.
- W2514515907 hasConcept C4937899 @default.
- W2514515907 hasConcept C55493867 @default.
- W2514515907 hasConcept C556039675 @default.
- W2514515907 hasConcept C71924100 @default.
- W2514515907 hasConceptScore W2514515907C142724271 @default.
- W2514515907 hasConceptScore W2514515907C176947019 @default.
- W2514515907 hasConceptScore W2514515907C178790620 @default.
- W2514515907 hasConceptScore W2514515907C185592680 @default.
- W2514515907 hasConceptScore W2514515907C195475562 @default.
- W2514515907 hasConceptScore W2514515907C204787440 @default.
- W2514515907 hasConceptScore W2514515907C2777810353 @default.
- W2514515907 hasConceptScore W2514515907C2778004101 @default.
- W2514515907 hasConceptScore W2514515907C2781263971 @default.
- W2514515907 hasConceptScore W2514515907C2781347565 @default.
- W2514515907 hasConceptScore W2514515907C43617362 @default.
- W2514515907 hasConceptScore W2514515907C4937899 @default.
- W2514515907 hasConceptScore W2514515907C55493867 @default.
- W2514515907 hasConceptScore W2514515907C556039675 @default.
- W2514515907 hasConceptScore W2514515907C71924100 @default.
- W2514515907 hasLocation W25145159071 @default.
- W2514515907 hasOpenAccess W2514515907 @default.
- W2514515907 hasPrimaryLocation W25145159071 @default.
- W2514515907 hasRelatedWork W1151398491 @default.
- W2514515907 hasRelatedWork W1964398531 @default.
- W2514515907 hasRelatedWork W1996713129 @default.
- W2514515907 hasRelatedWork W2011852842 @default.
- W2514515907 hasRelatedWork W2045356456 @default.
- W2514515907 hasRelatedWork W2065571723 @default.
- W2514515907 hasRelatedWork W2139589675 @default.
- W2514515907 hasRelatedWork W2232545056 @default.
- W2514515907 hasRelatedWork W2395031647 @default.
- W2514515907 hasRelatedWork W2561882575 @default.
- W2514515907 hasRelatedWork W2738147129 @default.
- W2514515907 hasRelatedWork W2795888105 @default.
- W2514515907 hasRelatedWork W2891845814 @default.
- W2514515907 hasRelatedWork W2892201104 @default.
- W2514515907 hasRelatedWork W2949927876 @default.
- W2514515907 hasRelatedWork W2952059896 @default.
- W2514515907 hasRelatedWork W3005964860 @default.
- W2514515907 hasRelatedWork W3094311321 @default.
- W2514515907 hasRelatedWork W3198404705 @default.
- W2514515907 hasRelatedWork W2345539942 @default.
- W2514515907 isParatext "false" @default.
- W2514515907 isRetracted "false" @default.
- W2514515907 magId "2514515907" @default.
- W2514515907 workType "article" @default.