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• W2514536084 abstract "Thanks to Filosso and associates for their comments on our article on bronchial carcinoid that appeared in CHEST (March 2002). 1 Rodriguez JA Meyers MO Jacome TH et al. Intraoperative detection of a bronchial carcinoid with a radiolabeled somatostatin analog. Chest. 2002; 121: 985-988 Abstract Full Text Full Text PDF PubMed Scopus (26) Google Scholar They refer to their report in 1997 in the Journal of Cardiovascular Surgery, 2 Oliaro A Filosso PL Bello M et al. Use of 111In-DTPA-octreotide scintigraphy in the diagnosis of neuroendocrine and non-neuroendocrine tumors of the lung: preliminary results. J Cardiovasc Surg. 1997; 38: 313-315 PubMed Google Scholar which we did not reference, as we acknowledged the work of Krenning and associates, 3 Krenning EP Bakker WH Breeman WA et al. Localization of endocrine-related tumours with a radioiodinated analogue of somatostatin. Lancet. 1989; 1: 242-244 Abstract PubMed Scopus (554) Google Scholar which antedated the work of Filosso and colleagues by a decade. Dr. Filosso points out that we did not perform an anatomic bilobectomy or a systematic mediastinal lymphadenectomy. It should be recalled that the patient had moderately severe mitral regurgitation with elevated pulmonary artery pressures. In addition, the intraoperative OctreoScan findings indicated no activity over the lymphatic drainage beds of the middle and lower lobes, and in our experience this is substantially more sensitive than the routine histologic examination of these nodes. 4 Woltering EA Barrie R O'Dorisio TM et al. Detection of occult gastrinomas with 125I-labeled lanreotide and intraoperative gamma detection. Surgery. 1994; 116: 1139-1146 PubMed Google Scholar Though useful for staging, I am aware of no evidence suggesting that mediastinal lymphadenectomy affects survival in patients with lung cancer or lung carcinoid tumors. Although not reported in our article, the patient underwent mitral valve replacement after recovering from her thoracic procedure in order to correct her mitral insufficiency. We felt that the equivalent of a segmentectomy was the appropriate intraoperative management for this patient. A frozen section was, of course, obtained during that original operative procedure. Intraoperative OctreoScan and Management of Bronchial CarcinoidCHESTVol. 122Issue 4PreviewWe read with interest the article of Rodriguez et al (March 2002),1 in which they pointed out the importance of 111In-diethylenetriamine pentaacetic acid pentetreotide (OctreoScan; Mallinckrodt-Tyco; St. Louis, MO) scintigraphy in the preoperative diagnosis and intraoperative management of bronchial carcinoid. In 1997, we2 published our preliminary results about our experience with OctreoScan in the preoperative diagnosis and postoperative follow-up of neuroendocrine and nonneuroendocrine tumors of the lung. Full-Text PDF" @default.
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• W2514536084 date "2002-10-01" @default.
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• W2514536084 title "Intraoperative OctreoScan and Management of Bronchial Carcinoid-To the Editor" @default.
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