Matches in SemOpenAlex for { <https://semopenalex.org/work/W2514607207> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2514607207 endingPage "1235" @default.
- W2514607207 startingPage "1225" @default.
- W2514607207 abstract "The efficacy of recombinant human superoxide dismutase (h-SOD) was examined and its optimal dose when given before reperfusion in an experimental canine cardiopulmonary bypass (CPB) model was determined. Mongrel dogs were placed on total CPB for 130 minutes without aortic cross clamping (Group I). Others were placed on CPB for 120 minutes aortic cross clamping with intermittent administration of cardioplegic solution and core cooling (Group II). Before reperfusion, saline, and 1 mg, 3 mg, 10 mg and 20 mg h-SOD per kilogram were administered via the aortic root as a bolus injection (Group III, IV, V, VI, VII). Reperfusion after hypothermic global ischemia with aortic cross clamping deteriorated cardiac function (cardiac index, left ventricular maximum dp/dt), increased myocardial water content and increased cardiac enzyme release (creatinine kinase MB isozyme, α-hydroxybutyric dehydrogenase). Administration of 3 mg/kg h-SOD significantly ameliorated this reperfusion injury, protected myocardial function early after CPB and gave a desirable peak serum h-SOD concentration." @default.
- W2514607207 created "2016-09-16" @default.
- W2514607207 creator A5074067640 @default.
- W2514607207 date "1991-01-01" @default.
- W2514607207 modified "2023-10-02" @default.
- W2514607207 title "The effects and optimal dose of recombinant human superoxide dismutase during cardiopulmonary bypass" @default.
- W2514607207 cites W103530802 @default.
- W2514607207 cites W1940436875 @default.
- W2514607207 cites W1967473422 @default.
- W2514607207 cites W1979241878 @default.
- W2514607207 cites W1991013811 @default.
- W2514607207 cites W1996710347 @default.
- W2514607207 cites W2001046546 @default.
- W2514607207 cites W2004985101 @default.
- W2514607207 cites W2011513090 @default.
- W2514607207 cites W2014254974 @default.
- W2514607207 cites W2026244960 @default.
- W2514607207 cites W2030855199 @default.
- W2514607207 cites W2034683799 @default.
- W2514607207 cites W2037121432 @default.
- W2514607207 cites W2050175937 @default.
- W2514607207 cites W2060933702 @default.
- W2514607207 cites W2077825836 @default.
- W2514607207 cites W2078523639 @default.
- W2514607207 cites W2103924942 @default.
- W2514607207 cites W2113146971 @default.
- W2514607207 cites W2130449129 @default.
- W2514607207 cites W2147461586 @default.
- W2514607207 cites W2147750240 @default.
- W2514607207 cites W2171980278 @default.
- W2514607207 cites W2395886970 @default.
- W2514607207 cites W2396070378 @default.
- W2514607207 cites W2405079146 @default.
- W2514607207 cites W2408752678 @default.
- W2514607207 cites W2418599777 @default.
- W2514607207 cites W2419508721 @default.
- W2514607207 cites W2474617437 @default.
- W2514607207 doi "https://doi.org/10.4044/joma1947.103.11-12_1225" @default.
- W2514607207 hasPublicationYear "1991" @default.
- W2514607207 type Work @default.
- W2514607207 sameAs 2514607207 @default.
- W2514607207 citedByCount "1" @default.
- W2514607207 countsByYear W25146072072023 @default.
- W2514607207 crossrefType "journal-article" @default.
- W2514607207 hasAuthorship W2514607207A5074067640 @default.
- W2514607207 hasBestOaLocation W25146072071 @default.
- W2514607207 hasConcept C111566952 @default.
- W2514607207 hasConcept C126322002 @default.
- W2514607207 hasConcept C164705383 @default.
- W2514607207 hasConcept C2775838275 @default.
- W2514607207 hasConcept C2776151105 @default.
- W2514607207 hasConcept C2777397205 @default.
- W2514607207 hasConcept C2778198053 @default.
- W2514607207 hasConcept C2778881276 @default.
- W2514607207 hasConcept C2779980429 @default.
- W2514607207 hasConcept C2780114680 @default.
- W2514607207 hasConcept C42219234 @default.
- W2514607207 hasConcept C43376680 @default.
- W2514607207 hasConcept C541997718 @default.
- W2514607207 hasConcept C71924100 @default.
- W2514607207 hasConceptScore W2514607207C111566952 @default.
- W2514607207 hasConceptScore W2514607207C126322002 @default.
- W2514607207 hasConceptScore W2514607207C164705383 @default.
- W2514607207 hasConceptScore W2514607207C2775838275 @default.
- W2514607207 hasConceptScore W2514607207C2776151105 @default.
- W2514607207 hasConceptScore W2514607207C2777397205 @default.
- W2514607207 hasConceptScore W2514607207C2778198053 @default.
- W2514607207 hasConceptScore W2514607207C2778881276 @default.
- W2514607207 hasConceptScore W2514607207C2779980429 @default.
- W2514607207 hasConceptScore W2514607207C2780114680 @default.
- W2514607207 hasConceptScore W2514607207C42219234 @default.
- W2514607207 hasConceptScore W2514607207C43376680 @default.
- W2514607207 hasConceptScore W2514607207C541997718 @default.
- W2514607207 hasConceptScore W2514607207C71924100 @default.
- W2514607207 hasIssue "11-12" @default.
- W2514607207 hasLocation W25146072071 @default.
- W2514607207 hasOpenAccess W2514607207 @default.
- W2514607207 hasPrimaryLocation W25146072071 @default.
- W2514607207 hasRelatedWork W1969729986 @default.
- W2514607207 hasRelatedWork W1975511334 @default.
- W2514607207 hasRelatedWork W2009398655 @default.
- W2514607207 hasRelatedWork W2048131422 @default.
- W2514607207 hasRelatedWork W2077825836 @default.
- W2514607207 hasRelatedWork W2078696152 @default.
- W2514607207 hasRelatedWork W2133278334 @default.
- W2514607207 hasRelatedWork W2205984738 @default.
- W2514607207 hasRelatedWork W2413034325 @default.
- W2514607207 hasRelatedWork W4282942326 @default.
- W2514607207 hasVolume "103" @default.
- W2514607207 isParatext "false" @default.
- W2514607207 isRetracted "false" @default.
- W2514607207 magId "2514607207" @default.
- W2514607207 workType "article" @default.