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• W2514785991 abstract "Myocardial perfusion SPECT is used in the non invasive assessment of coronary artery disease. This talk describes the design of new iterative reconstruction algorithms (IRR) and of heart-dedicated solid-state SPECT cameras for Myocardial Perfusion Imaging and discuss how these devices improve image quality while reducing study time and/or radiation dose to the patient. Methods The relative performances of IRR and gammacameras were studies over a wide range of acquisition count statistics, also in respect to conventional reconstruction software (OSEM and FBP), using an anthropomorphic phantom and selected physical figures of merit for image evaluation. Results and discussion IRR always determined significant improvements in all indices in comparison to FBP or OSEM. Their performances depend on the combined application of scatter and/or attenuation corrections that take full advantage of the capability of such algorithms. The impact of count statistics on the performances of IRR can be neglected down to a quarter of the reference study count statistics. As for the new solid state gammacameras D-SPECT showed a lower LV wall thickness and an inferior sharpness than D530c. No significant differences were found in terms of contrast or CNR. The regional normalized tracer uptake is maintained across all count densities up to a quarter of a standard study count statistic with conventional cameras and half with advanced systems. To compare data from the analysis of polar maps across different systems will require the adoption of specific normality databases, developed for each system coupled with the reconstruction method employed. Myocardial perfusion SPECT is used in the non invasive assessment of coronary artery disease. This talk describes the design of new iterative reconstruction algorithms (IRR) and of heart-dedicated solid-state SPECT cameras for Myocardial Perfusion Imaging and discuss how these devices improve image quality while reducing study time and/or radiation dose to the patient. The relative performances of IRR and gammacameras were studies over a wide range of acquisition count statistics, also in respect to conventional reconstruction software (OSEM and FBP), using an anthropomorphic phantom and selected physical figures of merit for image evaluation. IRR always determined significant improvements in all indices in comparison to FBP or OSEM. Their performances depend on the combined application of scatter and/or attenuation corrections that take full advantage of the capability of such algorithms. The impact of count statistics on the performances of IRR can be neglected down to a quarter of the reference study count statistics. As for the new solid state gammacameras D-SPECT showed a lower LV wall thickness and an inferior sharpness than D530c. No significant differences were found in terms of contrast or CNR. The regional normalized tracer uptake is maintained across all count densities up to a quarter of a standard study count statistic with conventional cameras and half with advanced systems. To compare data from the analysis of polar maps across different systems will require the adoption of specific normality databases, developed for each system coupled with the reconstruction method employed." @default.
• W2514785991 created "2016-09-16" @default.
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• W2514785991 date "2016-09-01" @default.
• W2514785991 modified "2023-09-24" @default.
• W2514785991 title "Performance evaluation of hardware and software for spect cardiac imaging" @default.
• W2514785991 doi "https://doi.org/10.1016/j.ejmp.2016.07.294" @default.
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