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- W2514833095 abstract "Carbon-based nanomaterials have a great potential as novel antibacterial agents; however, their interactions with bacteria are not fully understood. This study demonstrates that the antibacterial activity of graphene oxide (GO) depends on the physiological state of cells for both Gram-negative and -positive bacteria. GO susceptibility of bacteria is the highest in the exponential growth phase, which are in growing physiology, and stationary-phase (non-growing) cells are quite resistant against GO. Importantly, the order of GO susceptibility of E. coli with respect to the growth phases (exponential ≫ decline > stationary) correlates well with the changes in the envelope ultrastructures of the cells. Our findings are not only fundamentally important but also particularly critical for practical antimicrobial applications of carbon-based nanomaterials." @default.
- W2514833095 created "2016-09-16" @default.
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- W2514833095 date "2016-01-01" @default.
- W2514833095 modified "2023-10-16" @default.
- W2514833095 title "Bacterial physiology is a key modulator of the antibacterial activity of graphene oxide" @default.
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- W2514833095 doi "https://doi.org/10.1039/c6nr05745d" @default.
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