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- W2515133075 abstract "Cognitive models posit that social anxiety disorder (SAD) is associated with and maintained by attentional bias (AB) for social threat. However, over the last years, it has been suggested that AB in SAD may result from a decreased activation of the left prefrontal cortex, and particularly of its dorsolateral part (dlPFC). Accordingly, a transient increase of neural activity within the left dlPFC via non-invasive brain stimulation decreases AB in non-anxious control participants. Yet, none of these studies focused on SAD. This is especially unfortunate as SAD constitutes the main target for which a genuine reduction of AB may be most appropriate. In this experiment, we sought to investigate the causal influence of left dlPFC neuromodulation on AB among 19 female individuals with a DSM-5 diagnosis of SAD. We adopted a double-blind within-subject protocol in which we delivered a single-session of anodal versus sham transcranial Direct Current Stimulation (tDCS) over the left dlPFC during the completion of a probe discrimination task assessing AB. Consistent with our hypothesis, participants demonstrated a significant decrease in AB during the anodal tDCS over the left DLPFC relative to the sham stimulation. These findings value tDCS as an innovative procedure to gain new insight into the underlying mechanisms of SAD." @default.
- W2515133075 created "2016-09-16" @default.
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- W2515133075 date "2016-09-14" @default.
- W2515133075 modified "2023-10-18" @default.
- W2515133075 title "Impact of transcranial direct current stimulation on attentional bias for threat: a proof-of-concept study among individuals with social anxiety disorder" @default.
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- W2515133075 doi "https://doi.org/10.1093/scan/nsw119" @default.
- W2515133075 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5390730" @default.
- W2515133075 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27531388" @default.
- W2515133075 hasPublicationYear "2016" @default.
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