FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2515341249> ?p ?o ?g. }

• W2515341249 endingPage "93" @default.
• W2515341249 startingPage "93" @default.
• W2515341249 abstract "<p><strong>Objective: </strong>To evaluate the antiulcer<strong> </strong>activity of the most active sub-fraction of <em>Buchanania lanzan</em> Spreng. leaves methanolic extract (BLE).</p><p><strong>Methods: </strong>The antioxidant activity of BLE fractions and sub-fractions has been assayed to determine the most active sub-fraction by using <em>in vitro </em>antioxidant<em> </em>methods like hydrogen peroxide free radical scavenging assay, hydroxyl radical scavenging assay, DPPH (1, 1-diphenyl-2-picryl hydrazyl) radical scavenging activity, total flavonoid and total phenolic content estimation. Then, the antiulcerogenic activity of most active sub-fraction of BLE (50 and 100 mg/kg, b.w., orally) was evaluated employing<strong> a</strong>spirin+pylorus ligation-induced (APL) and HCl/ethanol-induced (HE) gastric ulcer models in rats, and histopathological examination of stomach tissues of rats.</p><p><strong>Results: </strong>The most active sub-fraction of BLE exerted a significant (<em>P&lt;</em>0.01) dose-dependent decrease in the ulcerative lesion index produced by APL and HE ulcer models in rats as compared to the standard drugs omeprazole (30 mg/kg, b.w. orally) and ranitidine (32 mg/kg, b.w. orally) respectively. The reduction in gastric fluid volume, total acidity and an increase in the pH of the gastric fluid in APL treated rats proved the antisecretory activity of most active subfraction of BLE. From histopathological examination, it was found that in tissues of both the models that received pretreatment with most activesub-fraction showed better protection of the gastric mucosa in a dose-dependent manner as indicated by reduction or absence of mucosal erosion and infiltration of leucocytes.</p><p><strong>Conclusion: </strong>These results suggest that leaves of <em>Buchanania lanzan </em>Spreng.<em> </em>possess potential antiulcer activity, which may be attributed to its antioxidant mechanism of action.</p>" @default.
• W2515341249 created "2016-09-16" @default.
• W2515341249 creator A5002273156 @default.
• W2515341249 creator A5047109988 @default.
• W2515341249 creator A5079666646 @default.
• W2515341249 date "2016-09-01" @default.
• W2515341249 modified "2023-10-16" @default.
• W2515341249 title "ANTIULCER ACTIVITY OF THE MOST ACTIVE SUB-FRACTION OF METHANOLIC LEAF EXTRACT OF BUCHANANIA LANZAN SPRENG" @default.
• W2515341249 cites W1500113782 @default.
• W2515341249 cites W1538764270 @default.
• W2515341249 cites W1559903407 @default.
• W2515341249 cites W1583489850 @default.
• W2515341249 cites W1971757462 @default.
• W2515341249 cites W2020371828 @default.
• W2515341249 cites W2031596649 @default.
• W2515341249 cites W2033135953 @default.
• W2515341249 cites W2044267297 @default.
• W2515341249 cites W2044554559 @default.
• W2515341249 cites W2046416025 @default.
• W2515341249 cites W2095071219 @default.
• W2515341249 cites W2109480244 @default.
• W2515341249 cites W2225439238 @default.
• W2515341249 cites W2244803838 @default.
• W2515341249 cites W2615939071 @default.
• W2515341249 cites W2617751790 @default.
• W2515341249 cites W796363722 @default.
• W2515341249 cites W2236904496 @default.
• W2515341249 doi "https://doi.org/10.22159/ijpps.2016.v8i9.12074" @default.
• W2515341249 hasPublicationYear "2016" @default.
• W2515341249 type Work @default.
• W2515341249 sameAs 2515341249 @default.
• W2515341249 citedByCount "1" @default.
• W2515341249 countsByYear W25153412492022 @default.
• W2515341249 crossrefType "journal-article" @default.
• W2515341249 hasAuthorship W2515341249A5002273156 @default.
• W2515341249 hasAuthorship W2515341249A5047109988 @default.
• W2515341249 hasAuthorship W2515341249A5079666646 @default.
• W2515341249 hasBestOaLocation W25153412491 @default.
• W2515341249 hasConcept C181199279 @default.
• W2515341249 hasConcept C185592680 @default.
• W2515341249 hasConcept C2777445857 @default.
• W2515341249 hasConcept C2778004101 @default.
• W2515341249 hasConcept C2778362808 @default.
• W2515341249 hasConcept C2779054382 @default.
• W2515341249 hasConcept C2780161600 @default.
• W2515341249 hasConcept C2781401929 @default.
• W2515341249 hasConcept C533411734 @default.
• W2515341249 hasConcept C538909803 @default.
• W2515341249 hasConcept C55493867 @default.
• W2515341249 hasConcept C71240020 @default.
• W2515341249 hasConcept C71924100 @default.
• W2515341249 hasConcept C98274493 @default.
• W2515341249 hasConceptScore W2515341249C181199279 @default.
• W2515341249 hasConceptScore W2515341249C185592680 @default.
• W2515341249 hasConceptScore W2515341249C2777445857 @default.
• W2515341249 hasConceptScore W2515341249C2778004101 @default.
• W2515341249 hasConceptScore W2515341249C2778362808 @default.
• W2515341249 hasConceptScore W2515341249C2779054382 @default.
• W2515341249 hasConceptScore W2515341249C2780161600 @default.
• W2515341249 hasConceptScore W2515341249C2781401929 @default.
• W2515341249 hasConceptScore W2515341249C533411734 @default.
• W2515341249 hasConceptScore W2515341249C538909803 @default.
• W2515341249 hasConceptScore W2515341249C55493867 @default.
• W2515341249 hasConceptScore W2515341249C71240020 @default.
• W2515341249 hasConceptScore W2515341249C71924100 @default.
• W2515341249 hasConceptScore W2515341249C98274493 @default.
• W2515341249 hasIssue "9" @default.
• W2515341249 hasLocation W25153412491 @default.
• W2515341249 hasOpenAccess W2515341249 @default.
• W2515341249 hasPrimaryLocation W25153412491 @default.
• W2515341249 hasRelatedWork W1978639042 @default.
• W2515341249 hasRelatedWork W2149176501 @default.
• W2515341249 hasRelatedWork W2182465068 @default.
• W2515341249 hasRelatedWork W2396157517 @default.
• W2515341249 hasRelatedWork W2535911039 @default.
• W2515341249 hasRelatedWork W4229335346 @default.
• W2515341249 hasRelatedWork W4283310851 @default.
• W2515341249 hasRelatedWork W2182960342 @default.
• W2515341249 hasRelatedWork W2185297438 @default.
• W2515341249 hasRelatedWork W2186694815 @default.
• W2515341249 hasVolume "8" @default.
• W2515341249 isParatext "false" @default.
• W2515341249 isRetracted "false" @default.
• W2515341249 magId "2515341249" @default.
• W2515341249 workType "article" @default.