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• W2515690545 startingPage "25" @default.
• W2515690545 abstract "Aspergillus spp. are a group of filamentous molds that were first described due to a perceived similarity to an aspergillum, or liturgical device used to sprinkle holy water, when viewed under a microscope. Although commonly inhaled due to their ubiquitous nature within the environment, an invasive fungal infection (IFI) is a rare outcome that is often reserved for those patients who are immunocompromised. Given the potential for significant morbidity and mortality within this patient population from IFI due to Aspergillus spp., along with the rise in the use of therapies that confer immunosuppression, there is an increasing need for appropriate initial clinical suspicion leading to accurate diagnosis and effective treatment. Voriconazole remains the first line agent for therapy; however, the use of polyenes, novel triazole agents, or voriconazole in combination with an echinocandin may also be utilized. Consideration as to which particular agent and for what duration should be made in the individual context for each patient based upon underlying immunosuppression, comorbidities, and overall tolerance of therapy." @default.
• W2515690545 created "2016-09-16" @default.
• W2515690545 creator A5066774127 @default.
• W2515690545 creator A5086011443 @default.
• W2515690545 date "2016-09-08" @default.
• W2515690545 modified "2023-09-25" @default.
• W2515690545 title "Treatment of Primary Pulmonary Aspergillosis: An Assessment of the Evidence" @default.
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• W2515690545 doi "https://doi.org/10.3390/jof2030025" @default.
• W2515690545 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5753138" @default.
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• W2515690545 hasPublicationYear "2016" @default.
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