FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2516146456> ?p ?o ?g. }

• W2516146456 endingPage "2074" @default.
• W2516146456 startingPage "2063" @default.
• W2516146456 abstract "Do self-management interventions in COPD patients work and which patients benefit most? An individual patient data meta-analysis Nini H Jonkman,1 Heleen Westland,1 Jaap CA Trappenburg,1 Rolf HH Groenwold,2 Erik WMA Bischoff,3 Jean Bourbeau,4 Christine E Bucknall,5 David Coultas,6 Tanja W Effing,7 Michael J Epton,8 Frode Gallefoss,9 Judith Garcia-Aymerich,10–12 Suzanne M Lloyd,13 Evelyn M Monninkhof,2 Huong Q Nguyen,14 Job van der Palen,15,16 Kathryn L Rice,17 Maria Sedeno,4 Stephanie JC Taylor,18 Thierry Troosters,19 Nicholas A Zwar,20 Arno W Hoes,2 Marieke J Schuurmans1 1Department of Rehabilitation, Nursing Science and Sports, 2Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, 3Department of Primary and Community Care, Radboud University Medical Center, Nijmegen, the Netherlands; 4Respiratory Epidemiology and Clinical Research Unit, Department of Medicine, McGill University Health Center, McGill University, Montreal, QC, Canada; 5Department of Respiratory Medicine, Glasgow Royal Infirmary, Glasgow, UK; 6Veterans Administration Portland Health Care System and Oregon Health & Science University, Portland, OR, USA; 7Department of Respiratory Medicine, Repatriation General Hospital, Adelaide, SA, Australia; 8Canterbury District Health Board, Respiratory Services, Christchurch Hospital, Christchurch, New Zealand; 9Department of Pulmonary Medicine, Sorlandet Hospital, Kristiansand, Norway; 10Centre for Research in Environmental Epidemiology CREAL, 11Pompeu Fabra University, 12CIBER Epidemiología y Salud Pública CIBERESP, Barcelona, Spain; 13Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK; 14Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA; 15Department of Research Methodology, Measurement and Data Analysis, University of Twente, 16Department of Clinical Epidemiology, Medisch Spectrum Twente, Enschede, the Netherlands; 17Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Minneapolis Veterans Affairs Health Care Service and University of Minnesota, Minneapolis, MN, USA; 18Centre for Primary Care and Public Health, Queen Mary University of London, London, UK; 19Department of Rehabilitation Sciences, Catholic University of Leuven, Leuven, Belgium; 20School of Public Health and Community Medicine, UNSW Australia, Sydney, NSW, Australia Background: Self-management interventions are considered effective in patients with COPD, but trials have shown inconsistent results and it is unknown which patients benefit most. This study aimed to summarize the evidence on effectiveness of self-management interventions and identify subgroups of COPD patients who benefit most.Methods: Randomized trials of self-management interventions between 1985 and 2013 were identified through a systematic literature search. Individual patient data of selected studies were requested from principal investigators and analyzed in an individual patient data meta-analysis using generalized mixed effects models.Results: Fourteen trials representing 3,282 patients were included. Self-management interventions improved health-related quality of life at 12 months (standardized mean difference 0.08, 95% confidence interval [CI] 0.00–0.16) and time to first respiratory-related hospitalization (hazard ratio 0.79, 95% CI 0.66–0.94) and all-cause hospitalization (hazard ratio 0.80, 95% CI 0.69–0.90), but had no effect on mortality. Prespecified subgroup analyses showed that interventions were more effective in males (6-month COPD-related hospitalization: interaction P=0.006), patients with severe lung function (6-month all-cause hospitalization: interaction P=0.016), moderate self-efficacy (12-month COPD-related hospitalization: interaction P=0.036), and high body mass index (6-month COPD-related hospitalization: interaction P=0.028 and 6-month mortality: interaction P=0.026). In none of these subgroups, a consistent effect was shown on all relevant outcomes.Conclusion: Self-management interventions exert positive effects in patients with COPD on respiratory-related and all-cause hospitalizations and modest effects on 12-month health-related quality of life, supporting the implementation of self-management strategies in clinical practice. Benefits seem similar across the subgroups studied and limiting self-management interventions to specific patient subgroups cannot be recommended. Keywords: chronic obstructive pulmonary disease, individual patient data meta-analysis, self-management, subgroup analysis" @default.
• W2516146456 created "2016-09-16" @default.
• W2516146456 creator A5000339384 @default.
• W2516146456 creator A5005535605 @default.
• W2516146456 creator A5006683717 @default.
• W2516146456 creator A5011839521 @default.
• W2516146456 creator A5014228703 @default.
• W2516146456 creator A5015729540 @default.
• W2516146456 creator A5024278490 @default.
• W2516146456 creator A5024846116 @default.
• W2516146456 creator A5027081774 @default.
• W2516146456 creator A5027541387 @default.
• W2516146456 creator A5027578432 @default.
• W2516146456 creator A5027866974 @default.
• W2516146456 creator A5032140143 @default.
• W2516146456 creator A5032508279 @default.
• W2516146456 creator A5043037176 @default.
• W2516146456 creator A5043983491 @default.
• W2516146456 creator A5047056781 @default.
• W2516146456 creator A5053266483 @default.
• W2516146456 creator A5054971562 @default.
• W2516146456 creator A5062890203 @default.
• W2516146456 creator A5066654444 @default.
• W2516146456 creator A5079739481 @default.
• W2516146456 creator A5084651750 @default.
• W2516146456 date "2016-08-01" @default.
• W2516146456 modified "2023-10-18" @default.
• W2516146456 title "Do self-management interventions in COPD patients work and which patients benefit most? An individual patient data meta-analysis" @default.
• W2516146456 cites W1642536113 @default.
• W2516146456 cites W1923600032 @default.
• W2516146456 cites W1973597670 @default.
• W2516146456 cites W1973905911 @default.
• W2516146456 cites W1990820477 @default.
• W2516146456 cites W2002726093 @default.
• W2516146456 cites W2018713883 @default.
• W2516146456 cites W2036326371 @default.
• W2516146456 cites W2036732164 @default.
• W2516146456 cites W2037377025 @default.
• W2516146456 cites W2040782437 @default.
• W2516146456 cites W2042148485 @default.
• W2516146456 cites W2042922430 @default.
• W2516146456 cites W2045340501 @default.
• W2516146456 cites W2048169226 @default.
• W2516146456 cites W2083436606 @default.
• W2516146456 cites W2084752662 @default.
• W2516146456 cites W2085069191 @default.
• W2516146456 cites W2085322115 @default.
• W2516146456 cites W2097667004 @default.
• W2516146456 cites W2100047554 @default.
• W2516146456 cites W2100389803 @default.
• W2516146456 cites W2107829061 @default.
• W2516146456 cites W2113178124 @default.
• W2516146456 cites W2115098571 @default.
• W2516146456 cites W2118502261 @default.
• W2516146456 cites W2120959053 @default.
• W2516146456 cites W2122691068 @default.
• W2516146456 cites W2123743870 @default.
• W2516146456 cites W2126356892 @default.
• W2516146456 cites W2127895332 @default.
• W2516146456 cites W2128452595 @default.
• W2516146456 cites W2129176787 @default.
• W2516146456 cites W2133120558 @default.
• W2516146456 cites W2134120248 @default.
• W2516146456 cites W2135828948 @default.
• W2516146456 cites W2139302805 @default.
• W2516146456 cites W2142945263 @default.
• W2516146456 cites W2143891168 @default.
• W2516146456 cites W2148044066 @default.
• W2516146456 cites W2155388082 @default.
• W2516146456 cites W2155638685 @default.
• W2516146456 cites W2158266555 @default.
• W2516146456 cites W2162350507 @default.
• W2516146456 cites W2163873720 @default.
• W2516146456 doi "https://doi.org/10.2147/copd.s107884" @default.
• W2516146456 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5012618" @default.
• W2516146456 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27621612" @default.
• W2516146456 hasPublicationYear "2016" @default.
• W2516146456 type Work @default.
• W2516146456 sameAs 2516146456 @default.
• W2516146456 citedByCount "51" @default.
• W2516146456 countsByYear W25161464562017 @default.
• W2516146456 countsByYear W25161464562018 @default.
• W2516146456 countsByYear W25161464562019 @default.
• W2516146456 countsByYear W25161464562020 @default.
• W2516146456 countsByYear W25161464562021 @default.
• W2516146456 countsByYear W25161464562022 @default.
• W2516146456 countsByYear W25161464562023 @default.
• W2516146456 crossrefType "journal-article" @default.
• W2516146456 hasAuthorship W2516146456A5000339384 @default.
• W2516146456 hasAuthorship W2516146456A5005535605 @default.
• W2516146456 hasAuthorship W2516146456A5006683717 @default.
• W2516146456 hasAuthorship W2516146456A5011839521 @default.
• W2516146456 hasAuthorship W2516146456A5014228703 @default.
• W2516146456 hasAuthorship W2516146456A5015729540 @default.
• W2516146456 hasAuthorship W2516146456A5024278490 @default.
• W2516146456 hasAuthorship W2516146456A5024846116 @default.
• W2516146456 hasAuthorship W2516146456A5027081774 @default.
• W2516146456 hasAuthorship W2516146456A5027541387 @default.

• next