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- W2516293696 abstract "Background: High risk patients for recurrent exacerbation of asthma and clinical characteristics related to death are major concern, but studies based on Korean population are rare. Methods: We recruited asthma patients who were over 18 years old and followed for at least 1 year at 4 University hospitals. Demographic characteristics, number of acute exacerbations in the previous year and lung function were recorded. Severe exacerbation was defined as which required admission, emergency visit or systemic steroid. Recurrent exacerbation was defined as at least twice events in a year. Results: 183 patients (mean age: 57 years, male 53.5%) were included. 15.9% of patients satisfied the ACOS criteria, 9.3% had major depression (PHQ- 9 score> 10) and 50.9% had allergic diseases. ICS/LABAs, LAMA and LTRA were prescribed to 80.7%, 18.9% and 25.4% of patients in each. Good compliance to inhaler (> 75%) was reported in 74.9%. 26.4% had acute exacerbation in the past year and severe exacerbations were reported in 23.9%. 13.7% showed recurrent exacerbations. Patients with recurrent exacerbation were more likely to have ACOS, uncontrolled asthma, concomitant depression and more frequent or severe exacerbation during the previous year. They took extra medication of LAMA, LTRA, theophylline, and oral corticosteroid. Among the patients with at least 1 year follow up after inclusion, 10.0% had recurrent exacerbation. Conclusions: Recurrent exacerbation was noted in 13.7% of our asthma cohort over a 1 year period. Depression, asthma control and ACOS were correlated with recurrent exacerbation." @default.
- W2516293696 created "2016-09-16" @default.
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- W2516293696 date "2015-09-01" @default.
- W2516293696 modified "2023-10-14" @default.
- W2516293696 title "Recurrent exacerbation of asthma: Characteristics of the patients and risk factors" @default.
- W2516293696 doi "https://doi.org/10.1183/13993003.congress-2015.pa5010" @default.
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