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- W25163598 abstract "ABSTRACT Time course studies of the effects of haloperidol (2 mg/kg) on alpha-methyltyrosine-induced dopamine fluorescence in the median eminence and on plasma prolactin levels showed that both dopamine turnover in the median eminence and prolactin levels are significantly increased 20 h after a single i.p, injection of haloperidol. Further, hypophysectomy prevents haloperidol-induced increase in dopamine turnover in the median eminence. Moreover, a marked increase in dopamine turnover in the median eminence was found 1, 5 and 10 weeks after chronic administration of haloperidol(about 1mg/kg/day). Haloperidol administration for a week caused a significant elevation of plasma prolactin levels. Our histochemical data suggests that tolerance does not develop to the effect of haloperidol-induced prolactin on dopamine turnover in rat median eminence." @default.
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- W25163598 date "1982-01-01" @default.
- W25163598 modified "2023-09-23" @default.
- W25163598 title "Acute and Chronic Effects of Haloperidol on Dopamine Fluorescence in the Median Eminence and on Plasma Prolactin Prolactin Levels in Rát" @default.
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- W25163598 doi "https://doi.org/10.1016/b978-0-08-027391-4.50029-0" @default.
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