FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2516454955> ?p ?o ?g. }

• W2516454955 endingPage "4731" @default.
• W2516454955 startingPage "4724" @default.
• W2516454955 abstract "Human papillomavirus (HPV) infection is the most common sexually transmitted disease worldwide. HPVs are oncogenic small double-stranded DNA viruses that are the primary causal agent of cervical cancer and other types of cancers, including in the anus, oropharynx, vagina, vulva, and penis. Prophylactic vaccination against HPV is an attractive strategy for preventing cervical cancer and some other types of cancers. However, there are few safe and effective vaccines against HPV infections. Current first-generation commercial HPV vaccines are expensive to produce and deliver. The goal of this study was to develop an alternate potent HPV recombinant L1-based vaccines by producing HPV virus-like particles into a vaccine that is currently used worldwide. Live attenuated measles virus (MV) vaccines have a well-established safety and efficacy record, and recombinant MV (rMV) produced by reverse genetics may be useful for generating candidate HPV vaccines to meet the needs of the developing world. We studied in non-human primate rMV-vectored HPV vaccine in parallel with a classical alum adjuvant recombinant HPV16L1 and 18L1 protein vaccine produced in Pichia pastoris. A combined prime-boost approach using both vaccines was evaluated, as well as immune interference due to pre-existing immunity against the MV. The humoral immune response induced by the MV, Pichia-expressed vaccine, and their combination as priming and boosting approaches was found to elicit HPV16L1 and 18L1 specific total IgG and neutralizing antibody titres. Pre-existing antibodies against measles did not prevent the immune response against HPV16L1 and 18L1." @default.
• W2516454955 created "2016-09-16" @default.
• W2516454955 creator A5027477987 @default.
• W2516454955 creator A5048127929 @default.
• W2516454955 creator A5065221278 @default.
• W2516454955 creator A5086033144 @default.
• W2516454955 date "2016-09-01" @default.
• W2516454955 modified "2023-10-13" @default.
• W2516454955 title "Immunogenicity of next-generation HPV vaccines in non-human primates: Measles-vectored HPV vaccine versus Pichia pastoris recombinant protein vaccine" @default.
• W2516454955 cites W1565564123 @default.
• W2516454955 cites W1581511516 @default.
• W2516454955 cites W1808115300 @default.
• W2516454955 cites W1955376530 @default.
• W2516454955 cites W1976154251 @default.
• W2516454955 cites W1979158612 @default.
• W2516454955 cites W1996539720 @default.
• W2516454955 cites W2001429203 @default.
• W2516454955 cites W2010237430 @default.
• W2516454955 cites W2021582018 @default.
• W2516454955 cites W2027654874 @default.
• W2516454955 cites W2028680945 @default.
• W2516454955 cites W2033497183 @default.
• W2516454955 cites W2039972112 @default.
• W2516454955 cites W2048017469 @default.
• W2516454955 cites W2063013193 @default.
• W2516454955 cites W2063364341 @default.
• W2516454955 cites W2101026209 @default.
• W2516454955 cites W2102795910 @default.
• W2516454955 cites W2121819501 @default.
• W2516454955 cites W2121966467 @default.
• W2516454955 cites W2127058706 @default.
• W2516454955 cites W2127913563 @default.
• W2516454955 cites W2132128610 @default.
• W2516454955 cites W2139736159 @default.
• W2516454955 cites W2162320594 @default.
• W2516454955 cites W2336475824 @default.
• W2516454955 cites W76787895 @default.
• W2516454955 doi "https://doi.org/10.1016/j.vaccine.2016.07.051" @default.
• W2516454955 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7126718" @default.
• W2516454955 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27523740" @default.
• W2516454955 hasPublicationYear "2016" @default.
• W2516454955 type Work @default.
• W2516454955 sameAs 2516454955 @default.
• W2516454955 citedByCount "19" @default.
• W2516454955 countsByYear W25164549552017 @default.
• W2516454955 countsByYear W25164549552018 @default.
• W2516454955 countsByYear W25164549552019 @default.
• W2516454955 countsByYear W25164549552020 @default.
• W2516454955 countsByYear W25164549552021 @default.
• W2516454955 countsByYear W25164549552022 @default.
• W2516454955 countsByYear W25164549552023 @default.
• W2516454955 crossrefType "journal-article" @default.
• W2516454955 hasAuthorship W2516454955A5027477987 @default.
• W2516454955 hasAuthorship W2516454955A5048127929 @default.
• W2516454955 hasAuthorship W2516454955A5065221278 @default.
• W2516454955 hasAuthorship W2516454955A5086033144 @default.
• W2516454955 hasBestOaLocation W25164549551 @default.
• W2516454955 hasConcept C121608353 @default.
• W2516454955 hasConcept C126322002 @default.
• W2516454955 hasConcept C159047783 @default.
• W2516454955 hasConcept C203014093 @default.
• W2516454955 hasConcept C22070199 @default.
• W2516454955 hasConcept C2777863537 @default.
• W2516454955 hasConcept C2778220009 @default.
• W2516454955 hasConcept C2778580637 @default.
• W2516454955 hasConcept C2780009117 @default.
• W2516454955 hasConcept C2780868878 @default.
• W2516454955 hasConcept C71924100 @default.
• W2516454955 hasConcept C86803240 @default.
• W2516454955 hasConcept C8891405 @default.
• W2516454955 hasConceptScore W2516454955C121608353 @default.
• W2516454955 hasConceptScore W2516454955C126322002 @default.
• W2516454955 hasConceptScore W2516454955C159047783 @default.
• W2516454955 hasConceptScore W2516454955C203014093 @default.
• W2516454955 hasConceptScore W2516454955C22070199 @default.
• W2516454955 hasConceptScore W2516454955C2777863537 @default.
• W2516454955 hasConceptScore W2516454955C2778220009 @default.
• W2516454955 hasConceptScore W2516454955C2778580637 @default.
• W2516454955 hasConceptScore W2516454955C2780009117 @default.
• W2516454955 hasConceptScore W2516454955C2780868878 @default.
• W2516454955 hasConceptScore W2516454955C71924100 @default.
• W2516454955 hasConceptScore W2516454955C86803240 @default.
• W2516454955 hasConceptScore W2516454955C8891405 @default.
• W2516454955 hasIssue "39" @default.
• W2516454955 hasLocation W25164549551 @default.
• W2516454955 hasLocation W25164549552 @default.
• W2516454955 hasLocation W25164549553 @default.
• W2516454955 hasOpenAccess W2516454955 @default.
• W2516454955 hasPrimaryLocation W25164549551 @default.
• W2516454955 hasRelatedWork W125184020 @default.
• W2516454955 hasRelatedWork W1992410431 @default.
• W2516454955 hasRelatedWork W1999684327 @default.
• W2516454955 hasRelatedWork W2018608294 @default.
• W2516454955 hasRelatedWork W2368503938 @default.
• W2516454955 hasRelatedWork W2393152609 @default.
• W2516454955 hasRelatedWork W2408983595 @default.
• W2516454955 hasRelatedWork W2432770450 @default.
• W2516454955 hasRelatedWork W2464521541 @default.

• next