FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2516477253> ?p ?o ?g. }

• W2516477253 endingPage "92" @default.
• W2516477253 startingPage "80" @default.
• W2516477253 abstract "The main clinical presentation of noncompaction myocardium (NCM) as nosologic unit are thromboembolic syndrome, heart failure, mostly ventricular arrhythmias and ischemia itself, related to insufficient myocardium blood supply under the noncompacted layer. Also, there are only sporadic cases of myocardial infarction described (MI), including “idiopathic”, in NCM. Aim. To check the prevalence of acute MI in patients with NCM, the specialties of clinical picture, diagnostics, and its probable specific mechanisms, influence on prognosis and its ways of prevention. Material and methods. Totally, 10 patients included, 7 males and 3 females, mean age — 46,3±15,8 y. o., (30 to 76 y. o.) among 85 patients with verified NCM diagnosis, set in accordance with harmonized visual criteria, and developed MI on this background. In 4 cases the NCM is confirmed with three visualizing criteria (EchoCG, MSCT, MRI of the heart), in 4 other — with the two. Mean follow-up was 10,5 [1,75; 32,25] months — from 1 month to 1 year. All patients underwent ECG, ambulatory ECG recording by Holter, EchoCG, assessment of antibodies against various heart antigens, PCR for DNA of parvovirus and B19, as well as herpes group, in blood; 7 coronary arteriographies, 7 MSCT of the heart, measurement of Troponin (n=7), morphological investigation of the heart with PCR-diagnostic of viral infection (n=6), MRI (n=5) and myocardium scintigraphy with 99mТс (n=6). Results . In 4 among 10 patients the development of MI was the first presentation of NCM. Prevalence of coronary atherosclerosis in those with MI and NCM was 20%, however in most cases development of MI was not related with coronary atherosclerosis. Intracardiac thrombosis was verified in 60% of patients with MI, embolism to other organs in 30%. The following mechanisms of MI established: 1) thromboembolism to coronary arteries if thrombi are present in the left chambers of the heart (atrium a. w.a. ventricle), verified in 1 patient at autopsy, and is suspected in other five; 2) concomitance of myocarditis, incl. viral, with microvasculitis development and thrombosis of intramyocardial arteries and focal necrosis in ischemized myocardium (n=6); 3) thrombosis of coronary arteries with presence of hemodynamically significant atherosclerosis (probably 1 patient); 4) sudden worsening of blood supply under noncompacted layer under the circumstances of low cardiac output by secondary origins. Conclusion. MI is typical and unrare complication of NCM: its prevalence reached 11,8% in separate registry of 85 patients with NCM syndrome. Four probable mechanisms of MI (necrosis) in NCM (embolism, thrombosis, myocarditis, microcirculation disorder) might be comorbid. The development of MI leads to serious worsening of the baseline systolic dysfunction and ventricular rhythm disorders: mortality among MI patients with NCM is 20% with the mean time of follow-up 10,5 months. As a preventive matter against MI in NCM should be concerned the anticoagulants at least for atrial fibrillation and in systolic dysfunction, on-time diagnostics and myocarditis management." @default.
• W2516477253 created "2016-09-16" @default.
• W2516477253 creator A5002345013 @default.
• W2516477253 creator A5005131515 @default.
• W2516477253 creator A5021092444 @default.
• W2516477253 creator A5025740885 @default.
• W2516477253 creator A5044192892 @default.
• W2516477253 creator A5047548554 @default.
• W2516477253 creator A5051793636 @default.
• W2516477253 creator A5069131585 @default.
• W2516477253 date "2016-01-01" @default.
• W2516477253 modified "2023-10-16" @default.
• W2516477253 title "MYOCARDIAL INFARCTION AS TYPICAL PRESENTATION OF NONCOMPACTION CARDIOMYOPATHY" @default.
• W2516477253 doi "https://doi.org/10.15829/1560-4071-2016-10-80-92" @default.
• W2516477253 hasPublicationYear "2016" @default.
• W2516477253 type Work @default.
• W2516477253 sameAs 2516477253 @default.
• W2516477253 citedByCount "3" @default.
• W2516477253 countsByYear W25164772532019 @default.
• W2516477253 countsByYear W25164772532022 @default.
• W2516477253 countsByYear W25164772532023 @default.
• W2516477253 crossrefType "journal-article" @default.
• W2516477253 hasAuthorship W2516477253A5002345013 @default.
• W2516477253 hasAuthorship W2516477253A5005131515 @default.
• W2516477253 hasAuthorship W2516477253A5021092444 @default.
• W2516477253 hasAuthorship W2516477253A5025740885 @default.
• W2516477253 hasAuthorship W2516477253A5044192892 @default.
• W2516477253 hasAuthorship W2516477253A5047548554 @default.
• W2516477253 hasAuthorship W2516477253A5051793636 @default.
• W2516477253 hasAuthorship W2516477253A5069131585 @default.
• W2516477253 hasBestOaLocation W25164772531 @default.
• W2516477253 hasConcept C126322002 @default.
• W2516477253 hasConcept C164705383 @default.
• W2516477253 hasConcept C2778198053 @default.
• W2516477253 hasConcept C2778797674 @default.
• W2516477253 hasConcept C500558357 @default.
• W2516477253 hasConcept C71924100 @default.
• W2516477253 hasConceptScore W2516477253C126322002 @default.
• W2516477253 hasConceptScore W2516477253C164705383 @default.
• W2516477253 hasConceptScore W2516477253C2778198053 @default.
• W2516477253 hasConceptScore W2516477253C2778797674 @default.
• W2516477253 hasConceptScore W2516477253C500558357 @default.
• W2516477253 hasConceptScore W2516477253C71924100 @default.
• W2516477253 hasIssue "10" @default.
• W2516477253 hasLocation W25164772531 @default.
• W2516477253 hasOpenAccess W2516477253 @default.
• W2516477253 hasPrimaryLocation W25164772531 @default.
• W2516477253 hasRelatedWork W1864361583 @default.
• W2516477253 hasRelatedWork W2316107365 @default.
• W2516477253 hasRelatedWork W2335083084 @default.
• W2516477253 hasRelatedWork W2367140913 @default.
• W2516477253 hasRelatedWork W2377483921 @default.
• W2516477253 hasRelatedWork W2384102316 @default.
• W2516477253 hasRelatedWork W2411183214 @default.
• W2516477253 hasRelatedWork W2443697580 @default.
• W2516477253 hasRelatedWork W2595649087 @default.
• W2516477253 hasRelatedWork W4247718175 @default.
• W2516477253 isParatext "false" @default.
• W2516477253 isRetracted "false" @default.
• W2516477253 magId "2516477253" @default.
• W2516477253 workType "article" @default.