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• W2516572573 abstract "The role of serum albumin level in patients with non-variceal upper gastrointestinal bleeding (NVUGB) has not been extensively studied. Our aim was to evaluate the role of serum albumin on admission in terms of in-hospital mortality in patients with NVUGB. Patients admitted with NVUGB during a 4-year period were prospectively included. Demographic, clinical, and laboratory data were collected. ROC curve analysis was used to determine the cutoff value for serum albumin on admission that made a distinction between deceased patients and survivors with respect to serum albumin on admission, as well as its overall performance compared with the Rockall score. 185 patients with NVUGB were evaluated. Men predominated (56.7%) and a mean age of 59.1 ± 19.9 years was found. Mean serum albumin on admission was 2.9 ± 0.9 g/dl with hypoalbuminemia (< 3.5 g/dl) detected on admission in 71.4% of cases. The ROC curve found that the best value for predicting hospital mortality was an albumin level of 3.1 g/dl (AUROC 0.738). Mortality in patients with albumin ≥ 3.2 g/dl was 1.2% compared with 11.2% in patients with albumin < 3.2 g/dl (P=.009; OR 9.7, 95%CI 1.2-76.5). There was no difference in overall performance between the albumin level (AUORC 0.738) and the Rockall score (AUROC 0.715) for identifying mortality. Patients with hypoalbuminemia presenting with NVUGB have a greater in-hospital mortality rate. The serum albumin level and the Rockall score perform equally in regard to identifying the mortality rate. El papel de los niveles séricos de albúmina en pacientes con sangrado de tubo digestivo alto no variceal (SDA-NV) no ha sido estudiado ampliamente. Nuestro objetivo fue evaluar el papel de los niveles de albúmina en la mortalidad de pacientes con SDA-NV. Se incluyó a pacientes con SDA-NV de forma prospectiva durante un periodo de 4 años. Se recolectaron datos demográficos, clínicos y de laboratorio. Se usó análisis ROC para determinar el mejor punto de corte para la albúmina sérica al momento de admisión que discrimine entre aquellos que sobrevivieron y aquellos que fallecieron, así como para comparar el desempeño global con la escala de Rockall. Ciento ochenta y cinco pacientes con SDA-NV fueron analizados. El sexo masculino predominó (56.7%) y la edad media fue de 59.1 ± 19.9 años. La media de albúmina al momento de admisión fue de 2.9 ± 0.9 g/dl, detectando hipoalbuminemia (< 3.5 g/dl) en el 71.4% de los casos. La curva ROC encontró un nivel de albúmina de 3.1 g/dl (AUROC 0.738) como el mejor punto de corte que predice mortalidad hospitalaria. La mortalidad en pacientes con albúmina ≥ 3.2 g/dl fue del 1.2% comparado con el 11.2% en el grupo con un valor < 3.2 g/dl (p = 0.009; RM 9.7, IC del 95%, 1.2-76.5). El desempeño global para identificar mortalidad fue similar entre albúmina (AUORC 0.738) y la escala de Rockall (AUROC 0.715). Los pacientes con SDA-NV con hipoalbuminemia presentan una mayor mortalidad hospitalaria. La albúmina sérica y la escala de Rockall mostraron un rendimiento similar para identificar mortalidad." @default.
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• W2516572573 date "2016-10-01" @default.
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• W2516572573 title "Hypoalbuminemia in the outcome of patients with non-variceal upper gastrointestinal bleeding" @default.
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• W2516572573 doi "https://doi.org/10.1016/j.rgmxen.2016.08.003" @default.
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