FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2517119803> ?p ?o ?g. }

• W2517119803 abstract "Collapsing Glomerulopathy (CG), also known as the collapsing variant of Focal Segmental Glomerulosclerosis (FSGS), is distinct in both its clinical severity and its pathophysiologic characteristics from other forms of FSGS. This lesion occurs disproportionally in patients carrying two APOL1 risk alleles, and is the classic histologic lesion resulting from Human Immunodeficiency Virus (HIV) infection of podocytes. Other viral infections, including parvovirus B19, and drugs such as interferon that perturb the immune system, have also been associated with CG. Despite significant advances, explaining such genetic and immune/infectious associations with causative mechanisms and supporting evidence has proven challenging.We report the case of a healthy (HIV-negative) pregnant 36 year-old Caribbean-American woman who presented with nephrotic syndrome and fetal demise in the setting of acute parvovirus B19 infection. A series of three renal biopsies and rapid clinical course showed progression from significant podocyte injury with mild light microscopy findings to classic viral-associated CG to ESRD in less than 3 months. Genetic analysis revealed two APOL1 G1 risk alleles.This is the first published case report of CG in the setting of acute parvovirus infection in a patient with two APOL1 risk allelles, and parvoviral proteins identified in renal epithelium on kidney biopsy. These findings support the causative role of parvovirus B19 infection in the development of CG on the background of APOL1 genetic risk." @default.
• W2517119803 created "2016-09-16" @default.
• W2517119803 creator A5005593819 @default.
• W2517119803 creator A5013539884 @default.
• W2517119803 creator A5034666118 @default.
• W2517119803 creator A5074284979 @default.
• W2517119803 creator A5080390560 @default.
• W2517119803 date "2016-09-06" @default.
• W2517119803 modified "2023-10-13" @default.
• W2517119803 title "Collapsing glomerulopathy in a young woman with APOL1 risk alleles following acute parvovirus B19 infection: a case report investigation" @default.
• W2517119803 cites W1531295370 @default.
• W2517119803 cites W1970584214 @default.
• W2517119803 cites W1978525119 @default.
• W2517119803 cites W2004577335 @default.
• W2517119803 cites W2008348389 @default.
• W2517119803 cites W2019946997 @default.
• W2517119803 cites W2022225331 @default.
• W2517119803 cites W2023694860 @default.
• W2517119803 cites W2028510371 @default.
• W2517119803 cites W2034888793 @default.
• W2517119803 cites W2042414076 @default.
• W2517119803 cites W2043698016 @default.
• W2517119803 cites W2044608847 @default.
• W2517119803 cites W2068378322 @default.
• W2517119803 cites W2071178601 @default.
• W2517119803 cites W2071311762 @default.
• W2517119803 cites W2083682221 @default.
• W2517119803 cites W2084857717 @default.
• W2517119803 cites W2085796905 @default.
• W2517119803 cites W2090385163 @default.
• W2517119803 cites W2092001580 @default.
• W2517119803 cites W2102493768 @default.
• W2517119803 cites W2112833823 @default.
• W2517119803 cites W2131352359 @default.
• W2517119803 cites W2136196249 @default.
• W2517119803 cites W2137096226 @default.
• W2517119803 cites W2143232661 @default.
• W2517119803 cites W2146597955 @default.
• W2517119803 cites W2148951685 @default.
• W2517119803 cites W2149616337 @default.
• W2517119803 cites W2152745352 @default.
• W2517119803 cites W2154949696 @default.
• W2517119803 cites W2157319364 @default.
• W2517119803 cites W2164500257 @default.
• W2517119803 cites W2167544906 @default.
• W2517119803 cites W2170767337 @default.
• W2517119803 cites W2373882499 @default.
• W2517119803 cites W4211123666 @default.
• W2517119803 cites W4255007839 @default.
• W2517119803 doi "https://doi.org/10.1186/s12882-016-0330-7" @default.
• W2517119803 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5013576" @default.
• W2517119803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27600725" @default.
• W2517119803 hasPublicationYear "2016" @default.
• W2517119803 type Work @default.
• W2517119803 sameAs 2517119803 @default.
• W2517119803 citedByCount "29" @default.
• W2517119803 countsByYear W25171198032017 @default.
• W2517119803 countsByYear W25171198032018 @default.
• W2517119803 countsByYear W25171198032019 @default.
• W2517119803 countsByYear W25171198032020 @default.
• W2517119803 countsByYear W25171198032021 @default.
• W2517119803 countsByYear W25171198032022 @default.
• W2517119803 countsByYear W25171198032023 @default.
• W2517119803 crossrefType "journal-article" @default.
• W2517119803 hasAuthorship W2517119803A5005593819 @default.
• W2517119803 hasAuthorship W2517119803A5013539884 @default.
• W2517119803 hasAuthorship W2517119803A5034666118 @default.
• W2517119803 hasAuthorship W2517119803A5074284979 @default.
• W2517119803 hasAuthorship W2517119803A5080390560 @default.
• W2517119803 hasBestOaLocation W25171198031 @default.
• W2517119803 hasConcept C126322002 @default.
• W2517119803 hasConcept C142724271 @default.
• W2517119803 hasConcept C203014093 @default.
• W2517119803 hasConcept C2522874641 @default.
• W2517119803 hasConcept C2778415529 @default.
• W2517119803 hasConcept C2779630601 @default.
• W2517119803 hasConcept C2780091579 @default.
• W2517119803 hasConcept C2780199430 @default.
• W2517119803 hasConcept C2780368995 @default.
• W2517119803 hasConcept C71924100 @default.
• W2517119803 hasConceptScore W2517119803C126322002 @default.
• W2517119803 hasConceptScore W2517119803C142724271 @default.
• W2517119803 hasConceptScore W2517119803C203014093 @default.
• W2517119803 hasConceptScore W2517119803C2522874641 @default.
• W2517119803 hasConceptScore W2517119803C2778415529 @default.
• W2517119803 hasConceptScore W2517119803C2779630601 @default.
• W2517119803 hasConceptScore W2517119803C2780091579 @default.
• W2517119803 hasConceptScore W2517119803C2780199430 @default.
• W2517119803 hasConceptScore W2517119803C2780368995 @default.
• W2517119803 hasConceptScore W2517119803C71924100 @default.
• W2517119803 hasIssue "1" @default.
• W2517119803 hasLocation W25171198031 @default.
• W2517119803 hasLocation W25171198032 @default.
• W2517119803 hasLocation W25171198033 @default.
• W2517119803 hasLocation W25171198034 @default.
• W2517119803 hasOpenAccess W2517119803 @default.
• W2517119803 hasPrimaryLocation W25171198031 @default.
• W2517119803 hasRelatedWork W2032596679 @default.
• W2517119803 hasRelatedWork W2062055742 @default.
• W2517119803 hasRelatedWork W2114725627 @default.

• next