Matches in SemOpenAlex for { <https://semopenalex.org/work/W2517775928> ?p ?o ?g. }
- W2517775928 endingPage "168" @default.
- W2517775928 startingPage "161" @default.
- W2517775928 abstract "Background:Statins reduce the incidence of cardiovascular events, but no randomized trial has investigated the best statins for secondary prevention. We compared the efficacy of hydrophilic pravastatin with that of lipophilic atorvastatin in patients with acute myocardial infarction (AMI).Methods and Results:A prospective, multicenter study enrolled 508 patients (410 men; mean age, 66.0±11.6 years) with AMI who were randomly assigned to atorvastatin (n=255) or pravastatin (n=253). The target control level of low-density lipoprotein cholesterol (LDL-C) was <100 mg/dl, and patients were followed for 2 years. The primary endpoint was the composite of death due to any cause, non-fatal myocardial infarction, non-fatal stroke, unstable angina or congestive heart failure requiring hospital admission, or any type of coronary revascularization. The primary endpoint occurred in 77 patients (30.4%) and in 80 patients (31.4%) in the pravastatin and atorvastatin groups, respectively (hazard ratio, 1.181; 95% confidence interval: 0.862–1.619; P=0.299), whereas greater reductions in serum total cholesterol and LDL-C were achieved in the atorvastatin group (P<0.001 for each). Changes in hemoglobin A1c, brain natriuretic peptide, and creatinine were not significant between the 2 regimens, and safety and treatment adherence were similar.Conclusions:On 2-year comparison of hydrophilic and lipophilic statins there was no significant difference in prevention of secondary cardiovascular outcome. (Circ J 2015; 79: 161–168)" @default.
- W2517775928 created "2016-09-16" @default.
- W2517775928 creator A5003098404 @default.
- W2517775928 creator A5004193056 @default.
- W2517775928 creator A5011574857 @default.
- W2517775928 creator A5012334490 @default.
- W2517775928 creator A5018256005 @default.
- W2517775928 creator A5018564240 @default.
- W2517775928 creator A5022012877 @default.
- W2517775928 creator A5036256585 @default.
- W2517775928 creator A5039218965 @default.
- W2517775928 creator A5075111300 @default.
- W2517775928 creator A5078239163 @default.
- W2517775928 creator A5081758735 @default.
- W2517775928 date "2014-01-01" @default.
- W2517775928 modified "2023-09-26" @default.
- W2517775928 title "Assessment of Lipophilic vs. Hydrophilic Statin Therapy in Acute Myocardial Infarction" @default.
- W2517775928 cites W110324665 @default.
- W2517775928 cites W1480665734 @default.
- W2517775928 cites W1973000825 @default.
- W2517775928 cites W1981595460 @default.
- W2517775928 cites W1982277398 @default.
- W2517775928 cites W1986680773 @default.
- W2517775928 cites W1995511200 @default.
- W2517775928 cites W2009063236 @default.
- W2517775928 cites W2015814654 @default.
- W2517775928 cites W2019488530 @default.
- W2517775928 cites W2027146649 @default.
- W2517775928 cites W2038338711 @default.
- W2517775928 cites W2047348709 @default.
- W2517775928 cites W2051864397 @default.
- W2517775928 cites W2058573028 @default.
- W2517775928 cites W2080427636 @default.
- W2517775928 cites W2089429897 @default.
- W2517775928 cites W2091135495 @default.
- W2517775928 cites W2092316845 @default.
- W2517775928 cites W2099618318 @default.
- W2517775928 cites W2101969945 @default.
- W2517775928 cites W2103918731 @default.
- W2517775928 cites W2105570905 @default.
- W2517775928 cites W2115169717 @default.
- W2517775928 cites W2116977954 @default.
- W2517775928 cites W2120289695 @default.
- W2517775928 cites W2126678006 @default.
- W2517775928 cites W2126830306 @default.
- W2517775928 cites W2134856703 @default.
- W2517775928 cites W2135234221 @default.
- W2517775928 cites W2136262759 @default.
- W2517775928 cites W2139168645 @default.
- W2517775928 cites W2143509464 @default.
- W2517775928 cites W2151405819 @default.
- W2517775928 cites W2157857368 @default.
- W2517775928 cites W2159449551 @default.
- W2517775928 cites W2161797812 @default.
- W2517775928 cites W2312192838 @default.
- W2517775928 cites W2330463397 @default.
- W2517775928 cites W3150426043 @default.
- W2517775928 cites W50178571 @default.
- W2517775928 cites W60172896 @default.
- W2517775928 doi "https://doi.org/10.1253/circj.cj-14-0877" @default.
- W2517775928 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25392071" @default.
- W2517775928 hasPublicationYear "2014" @default.
- W2517775928 type Work @default.
- W2517775928 sameAs 2517775928 @default.
- W2517775928 citedByCount "36" @default.
- W2517775928 countsByYear W25177759282014 @default.
- W2517775928 countsByYear W25177759282015 @default.
- W2517775928 countsByYear W25177759282016 @default.
- W2517775928 countsByYear W25177759282017 @default.
- W2517775928 countsByYear W25177759282018 @default.
- W2517775928 countsByYear W25177759282019 @default.
- W2517775928 countsByYear W25177759282020 @default.
- W2517775928 countsByYear W25177759282021 @default.
- W2517775928 countsByYear W25177759282022 @default.
- W2517775928 countsByYear W25177759282023 @default.
- W2517775928 crossrefType "journal-article" @default.
- W2517775928 hasAuthorship W2517775928A5003098404 @default.
- W2517775928 hasAuthorship W2517775928A5004193056 @default.
- W2517775928 hasAuthorship W2517775928A5011574857 @default.
- W2517775928 hasAuthorship W2517775928A5012334490 @default.
- W2517775928 hasAuthorship W2517775928A5018256005 @default.
- W2517775928 hasAuthorship W2517775928A5018564240 @default.
- W2517775928 hasAuthorship W2517775928A5022012877 @default.
- W2517775928 hasAuthorship W2517775928A5036256585 @default.
- W2517775928 hasAuthorship W2517775928A5039218965 @default.
- W2517775928 hasAuthorship W2517775928A5075111300 @default.
- W2517775928 hasAuthorship W2517775928A5078239163 @default.
- W2517775928 hasAuthorship W2517775928A5081758735 @default.
- W2517775928 hasBestOaLocation W25177759281 @default.
- W2517775928 hasConcept C126322002 @default.
- W2517775928 hasConcept C164705383 @default.
- W2517775928 hasConcept C168563851 @default.
- W2517775928 hasConcept C203092338 @default.
- W2517775928 hasConcept C207103383 @default.
- W2517775928 hasConcept C2776839432 @default.
- W2517775928 hasConcept C2777482532 @default.
- W2517775928 hasConcept C2777785093 @default.
- W2517775928 hasConcept C2778163477 @default.